Human VAP-B is involved in hepatitis C virus replication through interaction with NS5A and NS5B
about
Intrinsically unstructured domain 3 of hepatitis C Virus NS5A forms a "fuzzy complex" with VAPB-MSP domain which carries ALS-causing mutationsHepatitis C virus NS5B and host cyclophilin A share a common binding site on NS5AHuman butyrate-induced transcript 1 interacts with hepatitis C virus NS5A and regulates viral replicationHepatitis C virus RNA replication is regulated by FKBP8 and Hsp90A single-amino-acid mutation in hepatitis C virus NS5A disrupting FKBP8 interaction impairs viral replicationHepatitis C virus nonstructural protein 5A modulates the toll-like receptor-MyD88-dependent signaling pathway in macrophage cell linesRab18 binds to hepatitis C virus NS5A and promotes interaction between sites of viral replication and lipid dropletsCellular cofactors affecting hepatitis C virus infection and replicationInvolvement of creatine kinase B in hepatitis C virus genome replication through interaction with the viral NS4A proteinAssociation of hepatitis C virus replication complexes with microtubules and actin filaments is dependent on the interaction of NS3 and NS5AFFAT rescues VAPA-mediated inhibition of ER-to-Golgi transport and VAPB-mediated ER aggregationHuman VAP-C negatively regulates hepatitis C virus propagationDDX6 (Rck/p54) is required for efficient hepatitis C virus replication but not for internal ribosome entry site-directed translationThe yin and yang of hepatitis C: synthesis and decay of hepatitis C virus RNAAutophagy in hepatitis C virus-host interactions: potential roles and therapeutic targets for liver-associated diseasesThe NS3 Helicase and NS5B-to-3'X Regions Are Important for Efficient Hepatitis C Virus Strain JFH-1 Replication in Huh7 CellsReplication-Competent Recombinant Vesicular Stomatitis Virus Encoding Hepatitis C Virus Envelope ProteinsVisualization of Double-Stranded RNA in Cells Supporting Hepatitis C Virus RNA ReplicationHepatitis C Virus Induces E6AP-Dependent Degradation of the Retinoblastoma ProteinCyclophilin A Is an Essential Cofactor for Hepatitis C Virus Infection and the Principal Mediator of Cyclosporine Resistance In VitroRoles for endocytic trafficking and phosphatidylinositol 4-kinase III alpha in hepatitis C virus replicationCritical Role of Cyclophilin A and Its Prolyl-Peptidyl Isomerase Activity in the Structure and Function of the Hepatitis C Virus Replication ComplexRole of Oxysterol Binding Protein in Hepatitis C Virus infectionCochaperone Activity of Human Butyrate-Induced Transcript 1 Facilitates Hepatitis C Virus Replication through an Hsp90-Dependent PathwayTowards a small animal model for hepatitis CMembrane dynamics associated with viral infectionElucidating novel hepatitis C virus-host interactions using combined mass spectrometry and functional genomics approachesA combined proteomics/genomics approach links hepatitis C virus infection with nonsense-mediated mRNA decayIntegrating experimental and analytic approaches to improve data quality in genome-wide RNAi screensMetabolism of phosphatidylinositol 4-kinase IIIα-dependent PI4P Is subverted by HCV and is targeted by a 4-anilino quinazoline with antiviral activityHepatitis C virus RNA replication depends on specific cis- and trans-acting activities of viral nonstructural proteinsC-Terminal Auto-Regulatory Motif of Hepatitis C Virus NS5B Interacts with Human VAPB-MSP to Form a Dynamic Replication ComplexVinexin β Interacts with Hepatitis C Virus NS5A, Modulating Its Hyperphosphorylation To Regulate Viral Propagation.VAPC, an human endogenous inhibitor for hepatitis C virus (HCV) infection, is intrinsically unstructured but forms a "fuzzy complex" with HCV NS5B.Gene expression profiling indicates the roles of host oxidative stress, apoptosis, lipid metabolism, and intracellular transport genes in the replication of hepatitis C virus.Production of infectious hepatitis C virus by using RNA polymerase I-mediated transcription.Small molecules targeting hepatitis C virus-encoded NS5A cause subcellular redistribution of their target: insights into compound modes of action.Phosphorylation of hepatitis C virus RNA polymerases ser29 and ser42 by protein kinase C-related kinase 2 regulates viral RNA replication.The antiviral effector IFITM3 disrupts intracellular cholesterol homeostasis to block viral entry.Hepatitis C virus translation preferentially depends on active RNA replication.
P2860
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P2860
Human VAP-B is involved in hepatitis C virus replication through interaction with NS5A and NS5B
description
2005 nî lūn-bûn
@nan
2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Human VAP-B is involved in hep ...... interaction with NS5A and NS5B
@ast
Human VAP-B is involved in hep ...... interaction with NS5A and NS5B
@en
Human VAP-B is involved in hep ...... interaction with NS5A and NS5B
@en-gb
Human VAP-B is involved in hep ...... interaction with NS5A and NS5B
@nl
type
label
Human VAP-B is involved in hep ...... interaction with NS5A and NS5B
@ast
Human VAP-B is involved in hep ...... interaction with NS5A and NS5B
@en
Human VAP-B is involved in hep ...... interaction with NS5A and NS5B
@en-gb
Human VAP-B is involved in hep ...... interaction with NS5A and NS5B
@nl
altLabel
Human VAP-B Is Involved in Hep ...... Interaction with NS5A and NS5B
@en
prefLabel
Human VAP-B is involved in hep ...... interaction with NS5A and NS5B
@ast
Human VAP-B is involved in hep ...... interaction with NS5A and NS5B
@en
Human VAP-B is involved in hep ...... interaction with NS5A and NS5B
@en-gb
Human VAP-B is involved in hep ...... interaction with NS5A and NS5B
@nl
P2093
P2860
P921
P3181
P1433
P1476
Human VAP-B is involved in hep ...... interaction with NS5A and NS5B
@en
P2093
Hideki Aizaki
Itsuki Hamamoto
Kohji Moriishi
Takayuki Abe
Tatsuo Miyamura
Tetsuro Suzuki
Toru Okamoto
Yorihiro Nishimura
Yoshio Mori
P2860
P304
P3181
P356
10.1128/JVI.79.21.13473-13482.2005
P407
P577
2005-11-01T00:00:00Z