In vivo formation and repair of DNA double-strand breaks after computed tomography examinations - sprookjes - yvandenbroek - TriplyDB

In vivo formation and repair of DNA double-strand breaks after computed tomography examinations

In vivo formation and repair of DNA double-strand breaks after computed tomography examinations

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The linear no-threshold relationship is inconsistent with radiation biologic and experimental data Leukocyte DNA damage after reduced and conventional absorbed radiation doses using 3rd generation dual-source CT technology Evaluating biomarkers to model cancer risk post cosmic ray exposure Radiation signature on exposed cells: Relevance in dose estimation DNA damage signaling assessed in individual cells in relation to the cell cycle phase and induction of apoptosis Deoxyribonucleic acid damage-associated biomarkers of ionising radiation: current status and future relevance for radiology and radiotherapy Is the Linear No-Threshold Dose-Response Paradigm Still Necessary for the Assessment of Health Effects of Low Dose Radiation?Use of the γ-H2AX assay to monitor DNA damage and repair in translational cancer research Does iodinated contrast medium amplify DNA damage during exposure to radiation Radiation-induced cancer: a modern view Epidemiology Without Biology: False Paradigms, Unfounded Assumptions, and Specious Statistics in Radiation Science (with Commentaries by Inge Schmitz-Feuerhake and Christopher Busby and a Reply by the Authors)GammaH2AX and cancer Cytometry of ATM activation and histone H2AX phosphorylation to estimate extent of DNA damage induced by exogenous agents A two-mutation model of radiation-induced acute myeloid leukemia using historical mouse data.Low-dose or low-dose-rate ionizing radiation-induced bioeffects in animal models.The use of gamma-H2AX as a biodosimeter for total-body radiation exposure in non-human primates Accumulation of DNA damage in hematopoietic stem and progenitor cells during human aging.Analysis of individual molecular events of DNA damage response by flow- and image-assisted cytometry Inducible response required for repair of low-dose radiation damage in human fibroblasts.Review and evaluation of updated research on the health effects associated with low-dose ionising radiation.Histone gammaH2AX and poly(ADP-ribose) as clinical pharmacodynamic biomarkers.γ-H2AX foci are increased in lymphocytes in vivo in young children 1 h after very low-dose X-irradiation: a pilot study.Increased apoptosis and DNA double-strand breaks in the embryonic mouse brain in response to very low-dose X-rays but not 50 Hz magnetic fields.A prospective observational study of Gallium-68 ventilation and perfusion PET/CT during and after radiotherapy in patients with non-small cell lung cancer Evaluation of different biomarkers to predict individual radiosensitivity in an inter-laboratory comparison--lessons for future studies.Ionizing radiation-induced γ-H2AX activity in whole blood culture and the risk of lung cancer Evaluation of the efficacy of radiation-modifying compounds using γH2AX as a molecular marker of DNA double-strand breaks Recent developments in the use of γ-H2AX as a quantitative DNA double-strand break biomarker.X-ray induced formation of γ-H2AX foci after full-field digital mammography and digital breast-tomosynthesis.γH2AX foci as a measure of DNA damage: a computational approach to automatic analysis.Radiation exposure from imaging tests: is there an increased cancer risk?Gain of chromosome band 7q11 in papillary thyroid carcinomas of young patients is associated with exposure to low-dose irradiation γ-H2AX foci as in vivo effect biomarker in children emphasize the importance to minimize x-ray doses in paediatric CT imaging.Localized CT-guided irradiation inhibits neurogenesis in specific regions of the adult mouse brain.Variable activation of the DNA damage response pathways in patients undergoing single-photon emission computed tomography myocardial perfusion imaging.Induction and persistence of radiation-induced DNA damage is more pronounced in young animals than in old animals Pilot study for the establishment of biomarkers for radiation damage after computed tomography in children Q(γ-H2AX), an analysis method for partial-body radiation exposure using γ-H2AX in nonhuman primate lymphocytes.In vivo measurement of dose distribution in patients' lymphocytes: helical tomotherapy versus step-and-shoot IMRT in prostate cancer Calibration of the γ-H2AX DNA double strand break focus assay for internal radiation exposure of blood lymphocytes.

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In vivo formation and repair of DNA double-strand breaks after computed tomography examinations

http://www.wikidata.org/entity/Q24529558

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Proceedings of the National Academy of Sciences of the United States of America

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In vivo formation and repair o ...... mputed tomography examinations

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Christian Rübe

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Jochen Fleckenstein

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Markus Löbrich

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Martin Kühne

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Martina Heckmann

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Michael Uder

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Nicole Rief

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P2860

Cancer risks attributable to low doses of ionizing radiation: assessing what we really know

Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses

Megabase chromatin domains involved in DNA double-strand breaks in vivo

A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

Pathways of DNA double-strand break repair during the mammalian cell cycle

Radiation hormesis: data and interpretations.

Radiation carcinogenesis.

Low-dose hypersensitivity: current status and possible mechanisms.

Risk of cancer from diagnostic X-rays: estimates for the UK and 14 other countries.

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102

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