The use of gamma-H2AX as a biodosimeter for total-body radiation exposure in non-human primates - sprookjes - yvandenbroek - TriplyDB

The use of gamma-H2AX as a biodosimeter for total-body radiation exposure in non-human primates

The use of gamma-H2AX as a biodosimeter for total-body radiation exposure in non-human primates

http://www.wikidata.org/entity/Q33761113

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Leukocyte DNA damage after reduced and conventional absorbed radiation doses using 3rd generation dual-source CT technology Evaluating biomarkers to model cancer risk post cosmic ray exposure Use of the γ-H2AX assay to monitor DNA damage and repair in translational cancer research Heat shock protein 90α (Hsp90α) is phosphorylated in response to DNA damage and accumulates in repair foci Establishment of a γ-H2AX foci-based assay to determine biological dose of radon to red bone marrow in rats γ-H2AX/53BP1/pKAP-1 foci and their linear tracks induced by in vitro exposure to radon and its progeny in human peripheral blood lymphocytes Plasma miRNA as biomarkers for assessment of total-body radiation exposure dosimetry State-of-the-Art Advances in Radiation Biodosimetry for Mass Casualty Events Involving Radiation Exposure A phase I/II trial of belinostat in combination with cisplatin, doxorubicin, and cyclophosphamide in thymic epithelial tumors: a clinical and translational study.The RABiT: a rapid automated biodosimetry tool for radiological triage. II. Technological developments Gamma-H2AX-based dose estimation for whole and partial body radiation exposure γ-H2AX foci are increased in lymphocytes in vivo in young children 1 h after very low-dose X-irradiation: a pilot study.Circulating interleukin-18 as a biomarker of total-body radiation exposure in mice, minipigs, and nonhuman primates (NHP)A prospective observational study of Gallium-68 ventilation and perfusion PET/CT during and after radiotherapy in patients with non-small cell lung cancer ATR inhibitors VE-821 and VX-970 sensitize cancer cells to topoisomerase i inhibitors by disabling DNA replication initiation and fork elongation responses.Method for validating radiobiological samples using a linear accelerator.Recent developments in the use of γ-H2AX as a quantitative DNA double-strand break biomarker.Infrastructure to support ultra high throughput biodosimetry screening after a radiological event Q(γ-H2AX), an analysis method for partial-body radiation exposure using γ-H2AX in nonhuman primate lymphocytes.γ-H2AX Kinetic Profile in Mouse Lymphocytes Exposed to the Internal Emitters Cesium-137 and Strontium-90.Effect of dose rate on residual γ-H2AX levels and frequency of micronuclei in X-irradiated mouse lymphocytes γ-H2AX and other histone post-translational modifications in the clinic.90Y-daclizumab, an anti-CD25 monoclonal antibody, provided responses in 50% of patients with relapsed Hodgkin's lymphoma Wound trauma alters ionizing radiation dose assessment Radiation metabolomics. 5. Identification of urinary biomarkers of ionizing radiation exposure in nonhuman primates by mass spectrometry-based metabolomics New platform technology for comprehensive serological diagnostics of autoimmune diseases XRCC2 as a predictive biomarker for radioresistance in locally advanced rectal cancer patients undergoing preoperative radiotherapy.Evaluation of the gamma-H2AX assay for radiation biodosimetry in a swine model Unsolved mystery: the role of BRCA1 in DNA end-joining.Clinical and pharmacologic evaluation of two dosing schedules of indotecan (LMP400), a novel indenoisoquinoline, in patients with advanced solid tumors.DNA damage focus analysis in blood samples of minipigs reveals acute partial body irradiation.Wild-type p53-induced phosphatase 1 (Wip1) forestalls cellular premature senescence at physiological oxygen levels by regulating DNA damage response signaling during DNA replication.Radiation dose features and solid cancer induction in pediatric computed tomography.Complex DNA Damage: A Route to Radiation-Induced Genomic Instability and Carcinogenesis.Whole-blood immunoassay for γH2AX as a radiation biodosimetry assay with minimal sample preparation.Developing Human Radiation Biodosimetry Models: Testing Cross-Species Conversion Approaches Using an Ex Vivo Model System.On-chip radiation biodosimetry with three-dimensional microtissues.Quantitative estimation of DNA damage by photon irradiation based on the microdosimetric-kinetic model.Frequency of gamma H2AX foci in healthy volunteers and health workers occupationally exposed to X-irradiation and its relevance in biological dosimetry.The Causal Relationship between DNA Damage Induction in Bovine Lymphocytes and the Fukushima Nuclear Power Plant Accident.

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The use of gamma-H2AX as a biodosimeter for total-body radiation exposure in non-human primates

http://www.wikidata.org/entity/Q33761113

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2010 nî lūn-bûn

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2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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The use of gamma-H2AX as a bio ...... exposure in non-human primates

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The use of gamma-H2AX as a bio ...... exposure in non-human primates

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Arifur Rahman

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Asako J Nakamura

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Christophe E Redon

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Ksenia Gouliaeva

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William F Blakely

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William M Bonner

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Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence

In vivo formation and repair of DNA double-strand breaks after computed tomography examinations

Megabase chromatin domains involved in DNA double-strand breaks in vivo

Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers.

Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139

Computational analysis of the number, area and density of gamma-H2AX foci in breast cancer cells exposed to (111)In-DTPA-hEGF or gamma-rays using Image-J software

GammaH2AX and cancer

Detection of human papillomavirus types 6 and 11 in pubic and perianal hair from patients with genital warts.

Sample Tracking in an Automated Cytogenetic Biodosimetry Laboratory for Radiation Mass Casualties

Leukocyte DNA damage after multi-detector row CT: a quantitative biomarker of low-level radiation exposure.

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