Conformationally sensitive residues in extracellular loop 5 of the Na+/dicarboxylate co-transporter - sprookjes - yvandenbroek - TriplyDB

Conformationally sensitive residues in extracellular loop 5 of the Na+/dicarboxylate co-transporter

Conformationally sensitive residues in extracellular loop 5 of the Na+/dicarboxylate co-transporter

http://www.wikidata.org/entity/Q24531384

about

Mutations in the Na(+)/citrate cotransporter NaCT (SLC13A5) in pediatric patients with epilepsy and developmental delay Determinants of substrate and cation transport in the human Na+/dicarboxylate cotransporter NaDC3.Sodium-dependent extracellular accessibility of Lys-84 in the sodium/dicarboxylate cotransporter Role of isoleucine-554 in lithium binding by the Na+/dicarboxylate cotransporter NaDC1.Single nucleotide polymorphisms in the human Na+-dicarboxylate cotransporter affect transport activity and protein expression.Molecular properties of the SLC13 family of dicarboxylate and sulfate transporters Transmembrane helix 7 in the Na+/dicarboxylate cotransporter 1 is an outer helix that contains residues critical for function.Ala-504 is a determinant of substrate binding affinity in the mouse Na(+)/dicarboxylate cotransporter.Identification of a functionally critical GXXG motif and its relationship to the folate binding site of the proton-coupled folate transporter (PCFT-SLC46A1)Identification of transport pathways for citric acid cycle intermediates in the human colon carcinoma cell line, Caco-2.Structure-Based Identification of Inhibitors for the SLC13 Family of Na(+)/Dicarboxylate Cotransporters.Conserved aspartic acid residues lining the extracellular loop 1 of sodium-coupled bile acid transporter ASBT Interact with Na+ and 7alpha-OH moieties on the ligand cholestane skeleton.Transmembrane IV of the high-affinity sodium-glucose cotransporter participates in sugar binding Role of conserved prolines in the structure and function of the Na+/dicarboxylate cotransporter 1, NaDC1.Threonine-509 is a determinant of apparent affinity for both substrate and cations in the human Na+/dicarboxylate cotransporter Role of the tryptophan residues in proton-coupled folate transporter (PCFT-SLC46A1) function.Identification of conformationally sensitive amino acids in the Na(+)/dicarboxylate symporter (SdcS).Conformational flexibility of helix VI is essential for substrate permeation of the human apical sodium-dependent bile acid transporter Sodium-coupled dicarboxylate and citrate transporters from the SLC13 family.Discovery and Characterization of Novel GPR39 Agonists Allosterically Modulated by Zinc.Molecular Basis for Inhibition of the Na+/Citrate Transporter NaCT (SLC13A5) by Dicarboxylate Inhibitors.Functional characterization of SdcF from Bacillus licheniformis, a homolog of the SLC13 Na⁺/dicarboxylate transporters.

P2860

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P2860

Conformationally sensitive residues in extracellular loop 5 of the Na+/dicarboxylate co-transporter

http://www.wikidata.org/entity/Q24531384

description

2005 nî lūn-bûn

@nan

2005 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի մարտին հրատարակված գիտական հոդված

@hy

2005年の論文

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2005年論文

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2005年論文

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2005年論文

@zh-hk

2005年論文

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2005年論文

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2005年论文

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name

Conformationally sensitive res ...... +/dicarboxylate co-transporter

@ast

Conformationally sensitive res ...... +/dicarboxylate co-transporter

@en

Conformationally sensitive res ...... +/dicarboxylate co-transporter

@en-gb

Conformationally sensitive res ...... +/dicarboxylate co-transporter

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type

label

Conformationally sensitive res ...... +/dicarboxylate co-transporter

@ast

Conformationally sensitive res ...... +/dicarboxylate co-transporter

@en

Conformationally sensitive res ...... +/dicarboxylate co-transporter

@en-gb

Conformationally sensitive res ...... +/dicarboxylate co-transporter

@nl

prefLabel

Conformationally sensitive res ...... +/dicarboxylate co-transporter

@ast

Conformationally sensitive res ...... +/dicarboxylate co-transporter

@en

Conformationally sensitive res ...... +/dicarboxylate co-transporter

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Conformationally sensitive res ...... +/dicarboxylate co-transporter

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P1433

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P1476

Q24531384-1C2104DB-0FF8-4712-BAA8-EAD70CF66F8E

P2093

Q24531384-E9ED490D-FB7F-4760-9E75-9EAB84109F21

P2860

Q24531384-05222850-19EF-47BA-8AC0-421E601BE24D

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Q24531384-58411770-36ED-4F6E-9D23-56672D1BEE0D

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Q24531384-7435B263-8F19-41FE-9A95-4C98A4DFB0A0

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P304

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P31

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P356

Q24531384-140D6B89-3FD7-4084-B906-DE4996B6C241

P407

Q24531384-BDB4B61F-8C4D-4F10-87BC-175B0AA61487

P433

Q24531384-8F5DA3B0-01B0-4294-8475-898A6371FD63

P478

Q24531384-74811E0D-B8B1-43AB-8F0D-7F585281D91A

P50

Q24531384-118BB17F-430A-4285-87F2-9F71FA751742

P577

Q24531384-B28F717E-D7E4-49FC-A363-492025F07CDD

P698

Q24531384-B1018C45-5015-435A-AC4C-24D178DC0CAD

P921

Q24531384-3D5FBDFF-DF80-4EA8-8720-342C03187C04

P932

Q24531384-343DE74B-C9F6-4254-8893-C3D9E78A3392

P356

P1433

Journal of Biological Chemistry

P1476

Conformationally sensitive res ...... +/dicarboxylate co-transporter

@en

P2093

Ana M Pajor

http://www.w3.org/2001/XMLSchema#string

P2860

Rapid and efficient site-specific mutagenesis without phenotypic selection

The SLC13 gene family of sodium sulphate/carboxylate cotransporters

The interaction of the gamma-aminobutyric acid transporter GAT-1 with the neurotransmitter is selectively impaired by sulfhydryl modification of a conformationally sensitive cysteine residue engineered into extracellular loop IV

Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors

Structure, function, and genomic organization of human Na(+)-dependent high-affinity dicarboxylate transporter

Citrate transport by the kidney and intestine.

Molecular properties of sodium/dicarboxylate cotransporters.

Cysteine and disulfide scanning reveals a regulatory alpha-helix in the cytoplasmic domain of the aspartate receptor.

Flexible regions within the membrane-embedded portions of polytopic membrane proteins.

The plant homolog to the human sodium/dicarboxylic cotransporter is the vacuolar malate carrier.

P304

18728-18735

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P31

scholarly article

P356

10.1074/JBC.M501265200

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P407

P433

19

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P478

280

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P50

Kathleen M Randolph

P577

2005-03-17T00:00:00Z

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P698

15774465

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P921

P932

1224748

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