Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins. - sprookjes - yvandenbroek - TriplyDB

Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins.

Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins.

http://www.wikidata.org/entity/Q24537749

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Identification of two novel activities of the Wnt signaling regulator Dickkopf 3 and characterization of its expression in the mouse retina LDL receptor-related protein LRP6 regulates proliferation and survival through the Wnt cascade in vascular smooth muscle cells Functional characterization of WNT7A signaling in PC12 cells: interaction with A FZD5 x LRP6 receptor complex and modulation by Dickkopf proteins A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts Xenopus frizzled-4S, a splicing variant of Xfz4 is a context-dependent activator and inhibitor of Wnt/beta-catenin signaling.Modulating Dickkopf-1: A Strategy to Monitor or Treat Cancer?Structural Insight into the Mechanisms of Wnt Signaling Antagonism by Dkk Crystal structures of the extracellular domain of LRP6 and its complex with DKK1 Structural and Functional Studies of LRP6 Ectodomain Reveal a Platform for Wnt Signaling Structural Basis of Wnt Signaling Inhibition by Dickkopf Binding to LRP5/6 Dickkopf-3/REIC functions as a suppressor gene of tumor growth LRP6 expression promotes cancer cell proliferation and tumorigenesis by altering beta-catenin subcellular distribution Activation of Wnt signaling by chemically induced dimerization of LRP5 disrupts cellular homeostasis Differential gene expression between sensory neocortical areas: potential roles for Ten_m3 and Bcl6 in patterning visual and somatosensory pathways Wnt7b activates canonical signaling in epithelial and vascular smooth muscle cells through interactions with Fzd1, Fzd10, and LRP5.Wnt signaling in the murine diastema Generation and selection of novel fully human monoclonal antibodies that neutralize Dickkopf-1 (DKK1) inhibitory function in vitro and increase bone mass in vivo Human Dickkopf-1 (huDKK1) protein: characterization of glycosylation and determination of disulfide linkages in the two cysteine-rich domains.Epigenetic silencing of the WNT antagonist Dickkopf 3 disrupts normal Wnt/β-catenin signalling and apoptosis regulation in breast cancer cells Anti-Sclerostin antibody inhibits internalization of Sclerostin and Sclerostin-mediated antagonism of Wnt/LRP6 signaling.Dual-color dual-focus line-scanning FCS for quantitative analysis of receptor-ligand interactions in living specimens The Wnt inhibitor dickkopf-1: a link between breast cancer and bone metastases.Wnt3a-stimulated LRP6 phosphorylation is dependent upon arginine methylation of G3BP2.Chemical and genetic evidence for the involvement of Wnt antagonist Dickkopf2 in regulation of glucose metabolism.A soluble bone morphogenetic protein type IA receptor increases bone mass and bone strength.Pigment Epithelium-Derived Factor (PEDF) Inhibits Wnt/β-catenin Signaling in the Liver Zebrafish Dkk3a protein regulates the activity of myf5 promoter through interaction with membrane receptor integrin α6b The Wnt Antagonist Dickkopf-1 Promotes Pathological Type 2 Cell-Mediated Inflammation.Osteocytes, mechanosensing and Wnt signaling.Secreted and transmembrane wnt inhibitors and activators.Wnt signaling in vertebrate axis specification.Embryonic heart induction.Signaling pathways and preimplantation development of mammalian embryos.EWS/ETS regulates the expression of the Dickkopf family in Ewing family tumor cells.Increased liver carcinogenesis and enrichment of stem cell properties in livers of Dickkopf 2 (Dkk2) deleted mice.Canonical WNT signalling controls hair follicle spacing.Distinct roles of DKK1 and DKK2 in tumor angiogenesis.Wnt signalling and the control of cellular metabolism.Microenvironmental targeting of Wnt/beta-catenin signals for hematopoietic stem cell regulation.Wnt pathway antagonists and angiogenesis.

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Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins.

http://www.wikidata.org/entity/Q24537749

description

2002 nî lūn-bûn

@nan

2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins

@nl

Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins.

@ast

Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins.

@en

type

label

Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins

@nl

Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins.

@ast

Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins.

@en

prefLabel

Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins

@nl

Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins.

@ast

Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins.

@en

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MCB.22.17.6100-6110.2002

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Molecular and Cellular Biology

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Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins.

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Barbara K Brott

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Sergei Y Sokol

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P2860

A new secreted protein that binds to Wnt proteins and inhibits their activities

Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling

Functional and structural diversity of the human Dickkopf gene family

LDL-receptor-related proteins in Wnt signal transduction

Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow

Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6

Second cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelled

A beta-catenin/XTcf-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus

A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors

High-efficiency transformation of mammalian cells by plasmid DNA

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6100-6110

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4733093

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