Evidence for a telomere-independent "clock" limiting RAS oncogene-driven proliferation of human thyroid epithelial cells
about
Evolution of the cancer genomeProliferation and survival molecules implicated in the inhibition of BRAF pathway in thyroid cancer cells harbouring different genetic mutations.Macrophages, nitric oxide and microRNAs are associated with DNA damage response pathway and senescence in inflammatory bowel diseaseLong-term quiescent fibroblast cells transit into senescencePutative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions.Complex regulation of the cyclin-dependent kinase inhibitor p27kip1 in thyroid cancer cells by the PI3K/AKT pathway: regulation of p27kip1 expression and localizationUmbilical cord mesenchymal stromal cells affected by gestational diabetes mellitus display premature aging and mitochondrial dysfunctionProgressive transformation of immortalized esophageal epithelial cellsTelomere and telomerase in the initial stage of immortalization of esophageal epithelial cell.Normal human fibroblasts are resistant to RAS-induced senescenceCellular senescence and its effector programs.Identification of a </= 600-kb region on human chromosome 1q42.3 inducing cellular senescence.Novel colon cancer cell lines leading to better understanding of the diversity of respective primary cancers.Cell cycle arrest is sufficient for p53-mediated tumor regression.ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-Ras-induced DNA damage and subsequent senescence.Human fibroblast replicative senescence can occur in the absence of extensive cell division and short telomeres.Opposing effects of mutant ras oncoprotein on human fibroblast and epithelial cell proliferation: implications for models of human tumorigenesis.Ras triggers ataxia-telangiectasia-mutated and Rad-3-related activation and apoptosis through sustained mitogenic signaling.Sequential extension of proliferative lifespan in human fibroblasts induced by over-expression of CDK4 or 6 and loss of p53 function.
P2860
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P2860
Evidence for a telomere-independent "clock" limiting RAS oncogene-driven proliferation of human thyroid epithelial cells
description
2000 nî lūn-bûn
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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Evidence for a telomere-indepe ...... human thyroid epithelial cells
@ast
Evidence for a telomere-indepe ...... human thyroid epithelial cells
@en
Evidence for a telomere-indepe ...... human thyroid epithelial cells
@nl
type
label
Evidence for a telomere-indepe ...... human thyroid epithelial cells
@ast
Evidence for a telomere-indepe ...... human thyroid epithelial cells
@en
Evidence for a telomere-indepe ...... human thyroid epithelial cells
@nl
prefLabel
Evidence for a telomere-indepe ...... human thyroid epithelial cells
@ast
Evidence for a telomere-indepe ...... human thyroid epithelial cells
@en
Evidence for a telomere-indepe ...... human thyroid epithelial cells
@nl
P2093
P2860
P1476
Evidence for a telomere-indepe ...... human thyroid epithelial cells
@en
P2093
A Bounacer
D Wynford-Thomas
F S Wyllie
P2860
P304
P356
10.1128/MCB.20.15.5690-5699.2000
P407
P577
2000-08-01T00:00:00Z