Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo
about
Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapyZinc and copper modulate Alzheimer Abeta levels in human cerebrospinal fluidApoE promotes the proteolytic degradation of AbetaThe amyloid hypothesis of Alzheimer's disease at 25 yearsCandidate mechanisms underlying the association between sleep-wake disruptions and Alzheimer's diseaseExpanding the Repertoire of Biomarkers for Alzheimer's Disease: Targeted and Non-targeted ApproachesFluid Biomarkers in Clinical Trials of Alzheimer's Disease TherapeuticsTREM2 in CNS homeostasis and neurodegenerative diseaseImpaired vascular-mediated clearance of brain amyloid beta in Alzheimer's disease: the role, regulation and restoration of LRP1Clearance systems in the brain-implications for Alzheimer diseaseClinical trial methodologies for disease-modifying therapeutic approachesThe Glymphatic System: A Beginner's GuideAlzheimer's disease: Unique markers for diagnosis & new treatment modalitiesStatins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretionMolecular profiling reveals diversity of stress signal transduction cascades in highly penetrant Alzheimer's disease human skin fibroblastsAmyloid-beta isoform metabolism quantitation by stable isotope-labeled kineticsIn vivo human apolipoprotein E isoform fractional turnover rates in the CNSThe extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-β(1-40) peptideDecreased clearance of CNS beta-amyloid in Alzheimer's diseaseSleep drives metabolite clearance from the adult brainRapid, concurrent alterations in pre- and postsynaptic structure induced by naturally-secreted amyloid-beta protein.Increased in vivo amyloid-β42 production, exchange, and loss in presenilin mutation carriersThe concentration of soluble extracellular amyloid-β protein in acute brain slices from CRND8 mice.Imaging the Perivascular Space as a Potential Biomarker of Neurovascular and Neurodegenerative Diseases.Stable isotope labeling tandem mass spectrometry (SILT): integration with peptide identification and extension to data-dependent scansSelective modulation of amyloid-beta peptide degradation by flurbiprofen, fenofibrate, and related compounds regulates Abeta levels.Acute dosing of latrepirdine (Dimebon), a possible Alzheimer therapeutic, elevates extracellular amyloid-beta levels in vitro and in vivoMultimodal techniques for diagnosis and prognosis of Alzheimer's diseaseCNS amyloid-β, soluble APP-α and -β kinetics during BACE inhibition.Measurement of human surfactant protein-B turnover in vivo from tracheal aspirates using targeted proteomics.Cerebrospinal fluid biomarkers of Alzheimer's disease.Targeting Abeta and tau in Alzheimer's disease, an early interim reportContinuous 24-hour leptin, proopiomelanocortin, and amino acid measurements in human cerebrospinal fluid: correlations with plasma leptin, soluble leptin receptor, and amino acid levelsMultifaceted Roles of Metzincins in CNS Physiology and Pathology: From Synaptic Plasticity and Cognition to Neurodegenerative DisordersA novel Abeta isoform pattern in CSF reflects gamma-secretase inhibition in Alzheimer diseaseEnhancing astrocytic lysosome biogenesis facilitates Aβ clearance and attenuates amyloid plaque pathogenesisNeuronal heparan sulfates promote amyloid pathology by modulating brain amyloid-β clearance and aggregation in Alzheimer's disease.Picomolar amyloid-β peptides enhance spontaneous astrocyte calcium transientsFuture prospects for biomarkers of alcohol consumption and alcohol-induced disordersAcute gamma-secretase inhibition of nonhuman primate CNS shifts amyloid precursor protein (APP) metabolism from amyloid-beta production to alternative APP fragments without amyloid-beta rebound
P2860
Q24604376-AB197D67-F162-4E8D-A2E4-A49CD5DA90D5Q24649556-262F52E1-E4F9-4BFF-ACC7-197B3F42463FQ24651102-DEEA1107-4B3C-4C04-B6E1-85CD5121C2AAQ26749528-54B6B51C-EF10-4944-97F9-638FD18E985FQ26753192-DB91E1EF-1DD4-437B-A2C3-BC5A71FD7100Q26770708-6B5E8429-2961-475C-B4CB-D2220519A2EEQ26784569-57B1AE6F-1B9B-4A9E-8CCA-C1B32F9D437FQ26785919-F1C5399C-395C-49BE-850E-6F166A55B49DQ26800063-49666980-9B8D-4FA4-B15E-448CE2332BF3Q26801541-47A893BE-1B70-460D-92C1-D6F25051C978Q27001770-619FB396-6249-489D-9A1E-4B008424036CQ28084591-B3E798E0-5D93-4955-A98C-1D534BAAF623Q28085139-5612E553-464C-43F5-ADEA-A5595306197AQ28294279-628DB1EB-50C8-4A2A-9B03-D0926D8CB533Q28474877-16E7415F-4FF2-4AF9-9D25-35BDB7838C6CQ28681651-82F78A58-66D6-451D-A1D9-387B39714D3AQ28728902-37555AE2-BFF1-4087-8F73-CB5F7236C7FFQ28854601-6B5E8B85-55E2-4C74-A5A8-805DD2A28496Q29616534-868FE8BA-7A4C-48EF-ABA7-BDD038B1D087Q29620065-209F36C8-6967-4583-A6A1-BD95FB7BFB7FQ30481489-C37837A9-56F3-42A4-A8DA-C7C67E025264Q30557695-CBEAA7D9-1E8D-4C82-919C-E9774BCF32BAQ30994762-CF023D36-F282-4A5D-AB33-97D53A745503Q31060747-E6A1F046-9E25-4744-B9F9-B9A5779FC616Q33367347-CA803A57-0844-4327-9D93-5225037C362CQ33496258-A6039C71-6A70-482C-9238-75B36DE6E952Q33592247-EBF0E449-0455-4EDC-BBA7-34A56F505D50Q33607535-EC4543A4-7221-4C0D-8B38-6F0E5FD7884AQ33735544-FBE370B0-8BD9-4089-8CFC-24E4F7A2E8DFQ33744873-BA04BB50-6E7C-4D9B-A455-BFABF1C10F32Q33757828-1AF0E5D3-219F-4658-AE88-6078348A5C9AQ33829008-8CDE7D8B-64A2-4726-9328-B0A81D0CC4E0Q33837121-4A905675-4FBF-4A86-8E9F-A8A7EBF39124Q33854483-DE8C15E8-C1DB-4B5E-B2CE-0C3B3E193D89Q33877903-E138143E-DA5D-4C47-8BEC-9EAF64238667Q33906596-436C1A22-191E-492A-9918-F499553C0929Q33908201-1DE3C38A-43BB-43ED-9828-7D0DDE1821A7Q33975923-EAB9052A-A960-4A5C-A5F3-4C57066E24AFQ33976216-B9BF23EB-39B8-4B73-9DF2-6DAA570D07B2Q34036136-54B21853-0D38-4F5C-9686-A953FFD7AB79
P2860
Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo
description
2006 nî lūn-bûn
@nan
2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Human amyloid-beta synthesis a ...... in cerebrospinal fluid in vivo
@ast
Human amyloid-beta synthesis a ...... in cerebrospinal fluid in vivo
@en
Human amyloid-beta synthesis a ...... in cerebrospinal fluid in vivo
@nl
type
label
Human amyloid-beta synthesis a ...... in cerebrospinal fluid in vivo
@ast
Human amyloid-beta synthesis a ...... in cerebrospinal fluid in vivo
@en
Human amyloid-beta synthesis a ...... in cerebrospinal fluid in vivo
@nl
prefLabel
Human amyloid-beta synthesis a ...... in cerebrospinal fluid in vivo
@ast
Human amyloid-beta synthesis a ...... in cerebrospinal fluid in vivo
@en
Human amyloid-beta synthesis a ...... in cerebrospinal fluid in vivo
@nl
P2860
P50
P3181
P356
P1433
P1476
Human amyloid-beta synthesis a ...... in cerebrospinal fluid in vivo
@en
P2093
Ling Y Munsell
Robert Swarm
P2860
P2888
P304
P3181
P356
10.1038/NM1438
P407
P577
2006-07-01T00:00:00Z
P5875
P6179
1027986631