Dishevelled interacts with the DIX domain polymerization interface of Axin to interfere with its function in down-regulating β-catenin
about
Wnt/beta-catenin signaling and small molecule inhibitorsPtk7 and Mcc, Unfancied Components in Non-Canonical Wnt Signaling and CancerThe role of Ryk and Ror receptor tyrosine kinases in Wnt signal transductionCurrent Understanding on EGFR and Wnt/β-Catenin Signaling in Glioma and Their Possible CrosstalkTankyrase Sterile α Motif Domain Polymerization Is Required for Its Role in Wnt SignalingThe β-catenin destruction complexdifferent Roles for the axin interactions with the SAMP versus the second twenty amino acid repeat of adenomatous polyposis coliProtection of armadillo/β-Catenin by armless, a novel positive regulator of wingless signalingSpatio-temporal model of endogenous ROS and raft-dependent WNT/beta-catenin signaling driving cell fate commitment in human neural progenitor cellsTankyrase Inhibitors Stimulate the Ability of Tankyrases to Bind Axin and Drive Assembly of β-Catenin Degradation-Competent Axin PunctaA new mode of SAM domain mediated oligomerization observed in the CASKIN2 neuronal scaffolding protein.Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation.Wingless/Wnt signaling in Drosophila: the pattern and the pathwaySelf-association of the APC tumor suppressor is required for the assembly, stability, and activity of the Wnt signaling destruction complex.The Wnt/β-catenin pathway in human fibrotic-like diseases and its eligibility as a therapeutic target.Small-molecule modulation of Wnt signaling via modulating the Axin-LRP5/6 interaction.Ubiquitination of the Dishevelled DIX domain blocks its head-to-tail polymerizationA Comprehensive Overview of Skeletal Phenotypes Associated with Alterations in Wnt/β-catenin Signaling in Humans and Mice.Destruction complex function in the Wnt signaling pathway of Drosophila requires multiple interactions between Adenomatous polyposis coli 2 and ArmadilloThe Adenomatous polyposis coli tumour suppressor is essential for Axin complex assembly and function and opposes Axin's interaction with DishevelledRegulation of Wnt signaling by the tumor suppressor adenomatous polyposis coli does not require the ability to enter the nucleus or a particular cytoplasmic localization.A novel GSK3-regulated APC:Axin interaction regulates Wnt signaling by driving a catalytic cycle of efficient βcatenin destructionConformational change of Dishevelled plays a key regulatory role in the Wnt signaling pathwaysReversible modification of adenomatous polyposis coli (APC) with K63-linked polyubiquitin regulates the assembly and activity of the β-catenin destruction complex.Dual Roles for Membrane Association of Drosophila Axin in Wnt Signaling.Differential Roles of AXIN1 and AXIN2 in Tankyrase Inhibitor-Induced Formation of Degradasomes and β-Catenin DegradationThe two SAMP repeats and their phosphorylation state in Drosophila Adenomatous polyposis coli-2 play mechanistically distinct roles in negatively regulating Wnt signaling.Frizzled and LRP5/6 receptors for Wnt/β-catenin signalingAssembly of Dishevelled 3-based supermolecular complexes via phosphorylation and Axin.The Structure and Dynamics of Higher-Order Assemblies: Amyloids, Signalosomes, and Granules.Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling.New insights into the regulation of Axin function in canonical Wnt signaling pathway.Alternative Wnt pathways and receptors.Wnt signaling in vertebrate neural development and function.Toward a quantitative understanding of the Wnt/β-catenin pathway through simulation and experiment.Tankyrases as drug targets.Wnt signaling in remyelination in multiple sclerosis: friend or foe?Regulation of Wnt/β-catenin signaling by posttranslational modificationsProtein kinases and associated pathways in pluripotent state and lineage differentiation.Targeting Wnt signaling in colorectal cancer. A Review in the Theme: Cell Signaling: Proteins, Pathways and Mechanisms.
P2860
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P2860
Dishevelled interacts with the DIX domain polymerization interface of Axin to interfere with its function in down-regulating β-catenin
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Dishevelled interacts with the ...... n in down-regulating β-catenin
@ast
Dishevelled interacts with the ...... n in down-regulating β-catenin
@en
Dishevelled interacts with the ...... n in down-regulating β-catenin
@nl
type
label
Dishevelled interacts with the ...... n in down-regulating β-catenin
@ast
Dishevelled interacts with the ...... n in down-regulating β-catenin
@en
Dishevelled interacts with the ...... n in down-regulating β-catenin
@nl
prefLabel
Dishevelled interacts with the ...... n in down-regulating β-catenin
@ast
Dishevelled interacts with the ...... n in down-regulating β-catenin
@en
Dishevelled interacts with the ...... n in down-regulating β-catenin
@nl
P2093
P2860
P3181
P356
P1476
Dishevelled interacts with the ...... n in down-regulating β-catenin
@en
P2093
Carolina Mendoza-Topaz
Juliusz Mieszczanek
Marc Fiedler
Mariann Bienz
Trevor J Rutherford
P2860
P304
P3181
P356
10.1073/PNAS.1017063108
P407
P577
2011-02-01T00:00:00Z