Mapping the receptor site for alpha-scorpion toxins on a Na+ channel voltage sensor
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Biotechnological Trends in Spider and Scorpion Antivenom DevelopmentThe hitchhiker's guide to the voltage-gated sodium channel galaxyComputational Studies of Venom Peptides Targeting Potassium ChannelsFrom foe to friend: using animal toxins to investigate ion channel functionCrystal structure of a voltage-gated sodium channel in two potentially inactivated statesProton-dependent inhibition of the cardiac sodium channel Nav1.5 by ranolazineSelective spider toxins reveal a role for the Nav1.1 channel in mechanical painStructure and function of voltage-gated sodium channels at atomic resolution.Modular organization of α-toxins from scorpion venom mirrors domain structure of their targets, sodium channels.Synergetic action of domain II and IV underlies persistent current generation in Nav1.3 as revealed by a tarantula toxin.Scorpion venom components that affect ion-channels functionMolecular determinants of Hv1 proton channel inhibition by guanidine derivatives.Three charged amino acids in extracellular loop 1 are involved in maintaining the outer pore architecture of CFTR.Synthesis and analgesic effects of μ-TRTX-Hhn1b on models of inflammatory and neuropathic pain.Voltage-gated sodium channels at 60: structure, function and pathophysiology.Paxilline inhibits BK channels by an almost exclusively closed-channel block mechanism.Bacterial voltage-gated sodium channels (BacNa(V)s) from the soil, sea, and salt lakes enlighten molecular mechanisms of electrical signaling and pharmacology in the brain and heart.A surface plasmon resonance approach to monitor toxin interactions with an isolated voltage-gated sodium channel paddle motif.Direct evidence that scorpion α-toxins (site-3) modulate sodium channel inactivation by hindrance of voltage-sensor movementsThe Scorpion Toxin Tf2 from Tityus fasciolatus Promotes Nav1.3 Opening.Binding modes of μ-conotoxin to the bacterial sodium channel (NaVAb)Sequence variations at I260 and A1731 contribute to persistent currents in Drosophila sodium channels.Computer Simulations of Voltage-Gated Cation ChannelsTarget-Driven Evolution of Scorpion ToxinsAllosteric interactions between receptor site 3 and 4 of voltage-gated sodium channels: a novel perspective for the underlying mechanism of scorpion sting-induced pain.Mapping the interaction site for a β-scorpion toxin in the pore module of domain III of voltage-gated Na(+) channelsStructural Insights into the Atomistic Mechanisms of Action of Small Molecule Inhibitors Targeting the KCa3.1 Channel Pore.Finding Channels.Opening the shaker K+ channel with hanatoxin.Structure and function of hainantoxin-III, a selective antagonist of neuronal tetrodotoxin-sensitive voltage-gated sodium channels isolated from the Chinese bird spider Ornithoctonus hainana.Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels.Modulation of human Nav1.7 channel gating by synthetic α-scorpion toxin OD1 and its analogs.Computational methods of studying the binding of toxins from venomous animals to biological ion channels: theory and applications.Fluorescent protein-scorpion toxin chimera is a convenient molecular tool for studies of potassium channelsShellfish toxins targeting voltage-gated sodium channels.Characterization of a novel BmαTX47 toxin modulating sodium channels: the crucial role of expression vectors in toxin pharmacological activity.The insecticidal potential of venom peptides.Animal toxins influence voltage-gated sodium channel function.Molecular Simulations of Disulfide-Rich Venom Peptides with Ion Channels and Membranes.The Molecular Basis of Toxins' Interactions with Intracellular Signaling via Discrete Portals.
P2860
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P2860
Mapping the receptor site for alpha-scorpion toxins on a Na+ channel voltage sensor
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Mapping the receptor site for alpha-scorpion toxins on a Na+ channel voltage sensor
@ast
Mapping the receptor site for alpha-scorpion toxins on a Na+ channel voltage sensor
@en
Mapping the receptor site for alpha-scorpion toxins on a Na+ channel voltage sensor
@nl
type
label
Mapping the receptor site for alpha-scorpion toxins on a Na+ channel voltage sensor
@ast
Mapping the receptor site for alpha-scorpion toxins on a Na+ channel voltage sensor
@en
Mapping the receptor site for alpha-scorpion toxins on a Na+ channel voltage sensor
@nl
prefLabel
Mapping the receptor site for alpha-scorpion toxins on a Na+ channel voltage sensor
@ast
Mapping the receptor site for alpha-scorpion toxins on a Na+ channel voltage sensor
@en
Mapping the receptor site for alpha-scorpion toxins on a Na+ channel voltage sensor
@nl
P2093
P2860
P3181
P356
P1476
Mapping the receptor site for alpha-scorpion toxins on a Na+ channel voltage sensor
@en
P2093
Dalia Gordon
Jinti Wang
Michael Gurevitz
Todd Scheuer
Vladimir Yarov-Yarovoy
William A Catterall
P2860
P304
P3181
P356
10.1073/PNAS.1112320108
P407
P577
2011-09-13T00:00:00Z