Structure and function of hainantoxin-III, a selective antagonist of neuronal tetrodotoxin-sensitive voltage-gated sodium channels isolated from the Chinese bird spider Ornithoctonus hainana.
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Synergetic action of domain II and IV underlies persistent current generation in Nav1.3 as revealed by a tarantula toxin.The tarantula toxin β/δ-TRTX-Pre1a highlights the importance of the S1-S2 voltage-sensor region for sodium channel subtype selectivity.Bacterial voltage-gated sodium channels (BacNa(V)s) from the soil, sea, and salt lakes enlighten molecular mechanisms of electrical signaling and pharmacology in the brain and heart.Heterologous expression and purification of neurotoxic Hainantoxin-III in E. coli.Development of a μO-Conotoxin Analogue with Improved Lipid Membrane Interactions and Potency for the Analgesic Sodium Channel NaV1.8.Discovery of functional antibodies targeting ion channels.Plant cystine-knot peptides: pharmacological perspectives.Pharmacological characterization of potent and selective NaV1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V.Discovery of a Novel Na1.7 Inhibitor From Venom With Potent Analgesic EfficacyEngineering Gain-of-Function Analogues of the Spider Venom Peptide HNTX-I, A Potent Blocker of the hNa1.7 Sodium ChannelThe Na1.7 Channel Subtype as an Antinociceptive Target for Spider Toxins in Adult Dorsal Root Ganglia Neurons
P2860
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P2860
Structure and function of hainantoxin-III, a selective antagonist of neuronal tetrodotoxin-sensitive voltage-gated sodium channels isolated from the Chinese bird spider Ornithoctonus hainana.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on 23 May 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Structure and function of hain ...... spider Ornithoctonus hainana.
@en
Structure and function of hain ...... spider Ornithoctonus hainana.
@nl
type
label
Structure and function of hain ...... spider Ornithoctonus hainana.
@en
Structure and function of hain ...... spider Ornithoctonus hainana.
@nl
prefLabel
Structure and function of hain ...... spider Ornithoctonus hainana.
@en
Structure and function of hain ...... spider Ornithoctonus hainana.
@nl
P2093
P2860
P356
P1476
Structure and function of hain ...... spider Ornithoctonus hainana.
@en
P2093
Meichun Deng
Songping Liang
Tianfu Cai
P2860
P304
20392-20403
P356
10.1074/JBC.M112.426627
P407
P577
2013-05-23T00:00:00Z