Kallikreins are associated with secondary progressive multiple sclerosis and promote neurodegeneration - sprookjes - yvandenbroek - TriplyDB

Kallikreins are associated with secondary progressive multiple sclerosis and promote neurodegeneration

Kallikreins are associated with secondary progressive multiple sclerosis and promote neurodegeneration

http://www.wikidata.org/entity/Q24643613

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Kallikrein-related peptidase 12 hydrolyzes matricellular proteins of the CCN family and modifies interactions of CCN1 and CCN5 with growth factors Involvement of Kallikrein-Related Peptidases in Normal and Pathologic Processes What have we learned about the kallikrein-kinin and renin-angiotensin systems in neurological disorders?A completed KLK activome profile: investigation of activation profiles of KLK9, 10, and 15 Role of IL-33 and its receptor in T cell-mediated autoimmune diseases Functional role of kallikrein 6 in regulating immune cell survival.Critical role for PAR1 in kallikrein 6-mediated oligodendrogliopathy.Kallikrein cascades in traumatic spinal cord injury: in vitro evidence for roles in axonopathy and neuron degeneration.Kallikrein 6 signals through PAR1 and PAR2 to promote neuron injury and exacerbate glutamate neurotoxicity.Central neuroinvasion and demyelination by inflammatory macrophages after peripheral virus infection is controlled by SHP-1.Differential expression of multiple kallikreins in a viral model of multiple sclerosis points to unique roles in the innate and adaptive immune response.A non-synonymous SNP within membrane metalloendopeptidase-like 1 (MMEL1) is associated with multiple sclerosis.Correlation between KLK6 expression and the clinicopathological features of glioma.Interleukin-33 upregulation in peripheral leukocytes and CNS of multiple sclerosis patients.Kallikrein 6 regulates early CNS demyelination in a viral model of multiple sclerosis.Development of protein biomarkers in cerebrospinal fluid for secondary progressive multiple sclerosis using selected reaction monitoring mass spectrometry (SRM-MS)Genetic targeting of protease activated receptor 2 reduces inflammatory astrogliosis and improves recovery of function after spinal cord injury Development and immunochemical evaluation of a novel chicken IgY antibody specific for KLK6.Activation profiles of human kallikrein-related peptidases by proteases of the thrombostasis axis Modulation of macrophage infiltration and inflammatory activity by the phosphatase SHP-1 in virus-induced demyelinating disease Protease-activated receptor dependent and independent signaling by kallikreins 1 and 6 in CNS neuron and astroglial cell lines.The use of kallikrein-related peptidases as adjuvant prognostic markers in colorectal cancer.Macrophages of multiple sclerosis patients display deficient SHP-1 expression and enhanced inflammatory phenotype Kallikrein-related peptidases: bridges between immune functions and extracellular matrix degradation.The physiology and pathobiology of human kallikrein-related peptidase 6 (KLK6).Clinical biomarkers in multiple sclerosis.Predictions for the future of kallikrein-related peptidases in molecular diagnostics.Roles of kinins in the nervous system.Kallikrein-related peptidase 6 (KLK6)gene expression in intracranial tumors.Targeting the thrombin receptor modulates inflammation and astrogliosis to improve recovery after spinal cord injury Activation profiles of human kallikrein-related peptidases by matrix metalloproteinases.Kallikrein-related peptidase 6 exacerbates disease in an autoimmune model of multiple sclerosis.Kallikrein 6 secreted by oligodendrocytes regulates the progression of experimental autoimmune encephalomyelitis.Kallikrein-related peptidase 6: a biomarker for traumatic brain injury in the rat.Protease activated receptor 2 controls myelin development, resiliency and repair.Implication of the Kallikrein-Kinin system in neurological disorders: Quest for potential biomarkers and mechanisms.The Thrombin Receptor Restricts Subventricular Zone Neural Stem Cell Expansion and Differentiation.

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P2860

Kallikreins are associated with secondary progressive multiple sclerosis and promote neurodegeneration

http://www.wikidata.org/entity/Q24643613

description

2008 nî lūn-bûn

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2008 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2008 թվականի հունիսին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Kallikreins are associated wit ...... and promote neurodegeneration

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Kallikreins are associated wit ...... and promote neurodegeneration

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Kallikreins are associated wit ...... and promote neurodegeneration

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Kallikreins are associated wit ...... and promote neurodegeneration

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Kallikreins are associated wit ...... and promote neurodegeneration

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Kallikreins are associated wit ...... and promote neurodegeneration

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Kallikreins are associated wit ...... and promote neurodegeneration

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Kallikreins are associated wit ...... and promote neurodegeneration

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Kallikreins are associated wit ...... and promote neurodegeneration

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Biological Chemistry

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Kallikreins are associated wit ...... and promote neurodegeneration

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Alexander G Vandell

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Claudia F Lucchinetti

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Diane Sneve

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Isobel A Scarisbrick

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Mark Keegan

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Rachel Linbo

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Sachiko I Blaber

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P2860

Tissue-specific expression patterns and fine mapping of the human kallikrein (KLK) locus on proximal 19q13.4

Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region

The spectrum of human kallikrein 6 (zyme/protease M/neurosin) expression in human tissues as assessed by immunohistochemistry

A novel protease homolog differentially expressed in breast and ovarian cancer

Crystal structure and biochemical characterization of human kallikrein 6 reveals that a trypsin-like kallikrein is expressed in the central nervous system

Decreased concentration of human kallikrein 6 in brain extracts of Alzheimer's disease patients

Activity of a newly identified serine protease in CNS demyelination

A comprehensive nomenclature for serine proteases with homology to tissue kallikreins

The emerging roles of human tissue kallikreins in cancer

Molecular cloning of a novel trypsin-like serine protease (neurosin) preferentially expressed in brain

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739-45

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10.1515/BC.2008.085

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6

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389

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Eleftherios P. Diamandis

Moses Rodriguez

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2008-06-01T00:00:00Z

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18627300

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multiple sclerosis

clinical chemistry

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2580060

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