Rolipram, a type IV-specific phosphodiesterase inhibitor, facilitates the establishment of long-lasting long-term potentiation and improves memory
about
Inactivation of Pde8b enhances memory, motor performance, and protects against age-induced motor coordination decay.Rolipram: a specific phosphodiesterase 4 inhibitor with potential antipsychotic activity.Metaplasticity of the late-phase of long-term potentiation: a critical role for protein kinase A in synaptic taggingA mouse model of Rubinstein-Taybi syndrome: defective long-term memory is ameliorated by inhibitors of phosphodiesterase 4Age-related defects in spatial memory are correlated with defects in the late phase of hippocampal long-term potentiation in vitro and are attenuated by drugs that enhance the cAMP signaling pathwayPDE4 as a target for cognition enhancementPhosphodiesterase inhibition increases CREB phosphorylation and restores orientation selectivity in a model of fetal alcohol spectrum disordersPsychiatric aspects of phosphodiesterases: An overview.Human PDE4A8, a novel brain-expressed PDE4 cAMP-specific phosphodiesterase that has undergone rapid evolutionary changePhosphodiesterases as therapeutic targets for Alzheimer's disease.Environmental enrichment modifies the PKA-dependence of hippocampal LTP and improves hippocampus-dependent memoryRACK1 and β-arrestin2 attenuate dimerization of PDE4 cAMP phosphodiesterase PDE4D5Disrupted sleep without sleep curtailment induces sleepiness and cognitive dysfunction via the tumor necrosis factor-α pathwayERK regulation of phosphodiesterase 4 enhances dopamine-stimulated AMPA receptor membrane insertionA biphasic and brain-region selective down-regulation of cyclic adenosine monophosphate concentrations supports object recognition in the ratImpaired spatial learning and memory after sevoflurane-nitrous oxide anesthesia in aged rats is associated with down-regulated cAMP/CREB signalingGEBR-7b, a novel PDE4D selective inhibitor that improves memory in rodents at non-emetic dosesDifferential distribution of cAMP-specific phosphodiesterase 7A mRNA in rat brain and peripheral organsTranslating the frontiers of brain repair to treatments: starting not to break the rulesEnhanced expression of ADCY1 underlies aberrant neuronal signalling and behaviour in a syndromic autism model.Genetic and pharmacological evidence for schizophrenia-related Disc1 interaction with GSK-3.Epac signaling is required for hippocampus-dependent memory retrieval.PDE4 inhibition enhances hippocampal synaptic plasticity in vivo and rescues MK801-induced impairment of long-term potentiation and object recognition memory in an animal model of psychosisDevelopmental etiology for neuroanatomical and cognitive deficits in mice overexpressing Galphas, a G-protein subunit genetically linked to schizophrenia.Constitutive activation of Galphas within forebrain neurons causes deficits in sensorimotor gating because of PKA-dependent decreases in cAMP.Phosphodiesterase 11A in brain is enriched in ventral hippocampus and deletion causes psychiatric disease-related phenotypes.Zebrafish: An in vivo model for the study of neurological diseases.The cyclic AMP cascade is altered in the fragile X nervous systemRegulation of amygdalar PKA by beta-arrestin-2/phosphodiesterase-4 complex is critical for fear conditioningPhosphodiesterase Inhibitors as a Therapeutic Approach to Neuroprotection and Repair.Viagra for your synapses: Enhancement of hippocampal long-term potentiation by activation of beta-adrenergic receptors.Pharmacological Modulation of Functional Phenotypes of Microglia in Neurodegenerative DiseasesPhosphodiesterase type 1 inhibition improves learning in rats exposed to alcohol during the third trimester equivalent of human gestationPhosphodiesterase type 4 inhibition does not restore ocular dominance plasticity in a ferret model of fetal alcohol spectrum disorders.Flavonoid fisetin promotes ERK-dependent long-term potentiation and enhances memory.Brain region-specific decrease in the activity and expression of protein kinase A in the frontal cortex of regressive autism.A novel conditional genetic system reveals that increasing neuronal cAMP enhances memory and retrieval.Regulation of hippocampus-dependent memory by cyclic AMP-dependent protein kinaseIntracellular membrane association of the Aplysia cAMP phosphodiesterase long and short forms via different targeting mechanisms.Amyloid beta -peptide inhibition of the PKA/CREB pathway and long-term potentiation: reversibility by drugs that enhance cAMP signaling
P2860
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P2860
Rolipram, a type IV-specific phosphodiesterase inhibitor, facilitates the establishment of long-lasting long-term potentiation and improves memory
description
1998 nî lūn-bûn
@nan
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Rolipram, a type IV-specific p ...... tentiation and improves memory
@ast
Rolipram, a type IV-specific p ...... tentiation and improves memory
@en
Rolipram, a type IV-specific p ...... tentiation and improves memory
@nl
type
label
Rolipram, a type IV-specific p ...... tentiation and improves memory
@ast
Rolipram, a type IV-specific p ...... tentiation and improves memory
@en
Rolipram, a type IV-specific p ...... tentiation and improves memory
@nl
prefLabel
Rolipram, a type IV-specific p ...... tentiation and improves memory
@ast
Rolipram, a type IV-specific p ...... tentiation and improves memory
@en
Rolipram, a type IV-specific p ...... tentiation and improves memory
@nl
P2093
P2860
P3181
P356
P1476
Rolipram, a type IV-specific p ...... tentiation and improves memory
@en
P2093
D G Winder
R Bourtchouladze
P2860
P304
P3181
P356
10.1073/PNAS.95.25.15020
P407
P50
P577
1998-12-08T00:00:00Z