The murine Sim-2 gene product inhibits transcription by active repression and functional interference
about
Antiproliferative and apoptotic effects of selective phenolic acids on T47D human breast cancer cells: potential mechanisms of actionDifferential activities of murine single minded 1 (SIM1) and SIM2 on a hypoxic response element. Cross-talk between basic helix-loop-helix/per-Arnt-Sim homology transcription factorsIdentification of a novel basic helix-loop-helix-PAS factor, NXF, reveals a Sim2 competitive, positive regulatory role in dendritic-cytoskeleton modulator drebrin gene expressionRegulation of nuclear receptor transcriptional activity by a novel DEAD box RNA helicase (DP97)Cancer/Testis Antigen PASD1 Silences the Circadian ClockRecruitment of the NCoA/SRC-1/p160 family of transcriptional coactivators by the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator complexEpithelial-mesenchymal transition in cancer: parallels between normal development and tumor progressionARNT PAS-B has a fragile native state structure with an alternative -sheet register nearby in sequence spaceCellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alphaRecruitment of thyroid hormone receptor/retinoblastoma-interacting protein 230 by the aryl hydrocarbon receptor nuclear translocator is required for the transcriptional response to both dioxin and hypoxiaAryl hydrocarbon receptor imported into the nucleus following ligand binding is rapidly degraded via the cytosplasmic proteasome following nuclear exportSim2 mutants have developmental defects not overlapping with those of Sim1 mutantsTargeted disruption of the mPer3 gene: subtle effects on circadian clock function.Regulation of cardiovascular development and physiology by hypoxia-inducible factor 1.Different transcriptional properties of mSim-1 and mSim-2.The role of the transcription factor SIM2 in prostate cancer.Craniofacial abnormalities resulting from targeted disruption of the murine Sim2 gene.Dioxin exposure blocks lactation through a direct effect on mammary epithelial cells mediated by the aryl hydrocarbon receptor repressorDevelopment of neuroendocrine lineages requires the bHLH-PAS transcription factor SIM1.Sim2 prevents entry into the myogenic program by repressing MyoD transcription during limb embryonic myogenesis.Regulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1β (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites.The active form of human aryl hydrocarbon receptor (AHR) repressor lacks exon 8, and its Pro 185 and Ala 185 variants repress both AHR and hypoxia-inducible factorDisruption of period gene expression alters the inductive effects of dioxin on the AhR signaling pathway in the mouse liver.The bHLH/Per-Arnt-Sim transcription factor SIM2 regulates muscle transcript myomesin2 via a novel, non-canonical E-box sequence.PER and TIM inhibit the DNA binding activity of a Drosophila CLOCK-CYC/dBMAL1 heterodimer without disrupting formation of the heterodimer: a basis for circadian transcription.The HIF1alpha-inducible pro-cell death gene BNIP3 is a novel target of SIM2s repression through cross-talk on the hypoxia response element.Differential transcriptional regulation by mouse single-minded 2s.Mechanisms of ligand-induced aryl hydrocarbon receptor-mediated biochemical and toxic responses.Slow transition between two beta-strand registers is dictated by protein unfolding.Analysis of the transcriptional activation domain of the Drosophila tango bHLH-PAS transcription factor.SIM2 maintains innate host defense of the small intestine.Aryl Hydrocarbon Receptor Deficiency Alters Circadian and Metabolic Rhythmicity.Downregulation of hnRNP A2/B1 expression in tumor cells under prolonged hypoxia.
P2860
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P2860
The murine Sim-2 gene product inhibits transcription by active repression and functional interference
description
1997 nî lūn-bûn
@nan
1997 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
The murine Sim-2 gene product ...... on and functional interference
@ast
The murine Sim-2 gene product ...... on and functional interference
@en
The murine Sim-2 gene product ...... on and functional interference
@nl
type
label
The murine Sim-2 gene product ...... on and functional interference
@ast
The murine Sim-2 gene product ...... on and functional interference
@en
The murine Sim-2 gene product ...... on and functional interference
@nl
prefLabel
The murine Sim-2 gene product ...... on and functional interference
@ast
The murine Sim-2 gene product ...... on and functional interference
@en
The murine Sim-2 gene product ...... on and functional interference
@nl
P2093
P2860
P356
P1476
The murine Sim-2 gene product ...... on and functional interference
@en
P2093
P2860
P304
P356
10.1128/MCB.17.9.4933
P407
P577
1997-09-01T00:00:00Z