Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells
about
Genetic variants in EPAS1 contribute to adaptation to high-altitude hypoxia in SherpasExpression of DDX3 is directly modulated by hypoxia inducible factor-1 alpha in breast epithelial cellsCardiovascular basic helix loop helix factor 1, a novel transcriptional repressor expressed preferentially in the developing and adult cardiovascular systemCLIF, a novel cycle-like factor, regulates the circadian oscillation of plasminogen activator inhibitor-1 gene expressionDifferential activities of murine single minded 1 (SIM1) and SIM2 on a hypoxic response element. Cross-talk between basic helix-loop-helix/per-Arnt-Sim homology transcription factorsMammalian tumor suppressor Int6 specifically targets hypoxia inducible factor 2 alpha for degradation by hypoxia- and pVHL-independent regulationFIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factorHIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activityThe basic-helix-loop-helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factorsInduction of pyruvate dehydrogenase kinase-3 by hypoxia-inducible factor-1 promotes metabolic switch and drug resistanceThe candidate tumor suppressor ING4 represses activation of the hypoxia inducible factor (HIF).Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300.PAS kinase: an evolutionarily conserved PAS domain-regulated serine/threonine kinaseThe hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic developmentControl of distal antennal identity and tarsal development in Drosophila by spineless-aristapedia, a homolog of the mammalian dioxin receptorThe murine Sim-2 gene product inhibits transcription by active repression and functional interferenceThe human side of hypoxia-inducible factorHIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxiaRegulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathwayHypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1Transcriptional repression of human cad gene by hypoxia inducible factor-1alphaGenetic and epigenetic mechanisms in the development of arteriovenous malformations in the brainTargeting Protein-Protein Interactions in the HIF SystemHypoxia-Inducible Factors (HIFs) and Phosphorylation: Impact on Stability, Localization, and TransactivityExploring the HIFs, buts and maybes of hypoxia signalling in disease: lessons from zebrafish modelsHypoxia Inducible Factor Pathway and Physiological Adaptation: A Cell Survival Pathway?Hypoxic signaling during tissue repair and regenerative medicineOxygen sensing in retinal health and diseaseCancer-stromal cell interactions mediated by hypoxia-inducible factors promote angiogenesis, lymphangiogenesis, and metastasisInterplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogrammingPeripheral chemoreception and arterial pressure responses to intermittent hypoxiaHIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progressionIsolation and characterization of renal erythropoietin-producing cells from genetically produced anemia miceDifferential sub-nuclear distribution of hypoxia-inducible factors (HIF)-1 and -2 alpha impacts on their stability and mobility.Structural basis for PAS domain heterodimerization in the basic helix-loop-helix-PAS transcription factor hypoxia-inducible factorIdentification of Cys255 in HIF-1α as a novel site for development of covalent inhibitors of HIF-1α/ARNT PasB domain protein-protein interactionEvidence that the co-chaperone p23 regulates ligand responsiveness of the dioxin (Aryl hydrocarbon) receptorThe Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated MacrophagesIndependent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylationNERF2, a member of the Ets family of transcription factors, is increased in response to hypoxia and angiopoietin-1: a potential mechanism for Tie2 regulation during hypoxia
P2860
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P2860
Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells
description
1997 nî lūn-bûn
@nan
1997 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Endothelial PAS domain protein ...... expressed in endothelial cells
@ast
Endothelial PAS domain protein ...... expressed in endothelial cells
@en
Endothelial PAS domain protein ...... expressed in endothelial cells
@en-gb
Endothelial PAS domain protein ...... expressed in endothelial cells
@nl
type
label
Endothelial PAS domain protein ...... expressed in endothelial cells
@ast
Endothelial PAS domain protein ...... expressed in endothelial cells
@en
Endothelial PAS domain protein ...... expressed in endothelial cells
@en-gb
Endothelial PAS domain protein ...... expressed in endothelial cells
@nl
prefLabel
Endothelial PAS domain protein ...... expressed in endothelial cells
@ast
Endothelial PAS domain protein ...... expressed in endothelial cells
@en
Endothelial PAS domain protein ...... expressed in endothelial cells
@en-gb
Endothelial PAS domain protein ...... expressed in endothelial cells
@nl
P2093
P921
P3181
P356
P1433
P1476
Endothelial PAS domain protein ...... expressed in endothelial cells
@en
P2093
P3181
P356
10.1101/GAD.11.1.72
P407
P577
1997-01-01T00:00:00Z