An essential role for SKAP-55 in LFA-1 clustering on T cells that cannot be substituted by SKAP-55R
about
Regulation and function of SKAP-55 non-canonical motif binding to the SH3c domain of adhesion and degranulation-promoting adaptor proteinThe ADAP/SKAP55 signaling module regulates T-cell receptor-mediated integrin activation through plasma membrane targeting of Rap1Memory T Cell MigrationAutoimmune therapies targeting costimulation and emerging trends in multivalent therapeuticsRIAM links the ADAP/SKAP-55 signaling module to Rap1, facilitating T-cell-receptor-mediated integrin activationThe N terminus of SKAP55 enables T cell adhesion to TCR and integrin ligands via distinct mechanisms.SLP-76-ADAP adaptor module regulates LFA-1 mediated costimulation and T cell motility.Macrophages require Skap2 and Sirpα for integrin-stimulated cytoskeletal rearrangement.LRCH1 interferes with DOCK8-Cdc42-induced T cell migration and ameliorates experimental autoimmune encephalomyelitis.Adaptor SKAP-55 binds p21 activating exchange factor RasGRP1 and negatively regulates the p21-ERK pathway in T-cells.HPK1 associates with SKAP-HOM to negatively regulate Rap1-mediated B-lymphocyte adhesion.CTLA-4 up-regulation of lymphocyte function-associated antigen 1 adhesion and clustering as an alternate basis for coreceptor function.Adapters in the organization of mast cell signaling.ADAP and SKAP55 deficiency suppresses PD-1 expression in CD8+ cytotoxic T lymphocytes for enhanced anti-tumor immunotherapy.Distinct regulation of integrin-dependent T cell conjugate formation and NF-kappa B activation by the adapter protein ADAP.SKAP-55, SKAP-55-related and ADAP adaptors modulate integrin-mediated immune-cell adhesion.T cell receptor "inside-out" pathway via signaling module SKAP1-RapL regulates T cell motility and interactions in lymph nodesThe ins and outs of leukocyte integrin signaling.Gene related to anergy in lymphocytes (GRAIL) expression in CD4+ T cells impairs actin cytoskeletal organization during T cell/antigen-presenting cell interactionsIntegrin signalling and function in immune cells.Adaptor regulation of LFA-1 signaling in T lymphocyte migration: Potential druggable targets for immunotherapies?SKAP1 protein PH domain determines RapL membrane localization and Rap1 protein complex formation for T cell receptor (TCR) activation of LFA-1.SKAP1 is dispensable for chemokine-induced migration of primary T-cellsFunctional defects of SKAP-55-deficient T cells identify a regulatory role for the adaptor in LFA-1 adhesionCD8+ Effector T Cell Migration to Pancreatic Islet Grafts Is Dependent on Cognate Antigen Presentation by Donor Graft CellsNon-cleavable talin rescues defect in the T-cell conjugation of T-cells deficient in the immune adaptor SKAP1.T-cell immune adaptor SKAP1 regulates the induction of collagen-induced arthritis in mice.Regulation of in vitro and in vivo immune functions by the cytosolic adaptor protein SKAP-HOM.
P2860
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P2860
An essential role for SKAP-55 in LFA-1 clustering on T cells that cannot be substituted by SKAP-55R
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
An essential role for SKAP-55 ...... not be substituted by SKAP-55R
@ast
An essential role for SKAP-55 ...... not be substituted by SKAP-55R
@en
An essential role for SKAP-55 ...... not be substituted by SKAP-55R
@nl
type
label
An essential role for SKAP-55 ...... not be substituted by SKAP-55R
@ast
An essential role for SKAP-55 ...... not be substituted by SKAP-55R
@en
An essential role for SKAP-55 ...... not be substituted by SKAP-55R
@nl
prefLabel
An essential role for SKAP-55 ...... not be substituted by SKAP-55R
@ast
An essential role for SKAP-55 ...... not be substituted by SKAP-55R
@en
An essential role for SKAP-55 ...... not be substituted by SKAP-55R
@nl
P2093
P2860
P3181
P356
P1476
An essential role for SKAP-55 ...... not be substituted by SKAP-55R
@en
P2093
Christopher E Rudd
Eun-Kyeong Jo
Hongyan Wang
P2860
P304
P3181
P356
10.1084/JEM.20042577
P407
P577
2005-06-06T00:00:00Z