SCHEMA recombination of a fungal cellulase uncovers a single mutation that contributes markedly to stability - sprookjes - yvandenbroek - TriplyDB

SCHEMA recombination of a fungal cellulase uncovers a single mutation that contributes markedly to stability

SCHEMA recombination of a fungal cellulase uncovers a single mutation that contributes markedly to stability

http://www.wikidata.org/entity/Q24648550

about

Beyond directed evolution--semi-rational protein engineering and design Protein stability: computation, sequence statistics, and new experimental methods Engineered thermostable fungal Cel6A and Cel7A cellobiohydrolases hydrolyze cellulose efficiently at elevated temperatures Directed evolution: tailoring biocatalysts for industrial applications Endoglucanases: insights into thermostability for biofuel applications Modulating the thermostability of Endoglucanase I from Trichoderma reesei using computational approaches.Designing specific protein-protein interactions using computation, experimental library screening, or integrated methods Directed evolution strategies for enantiocomplementary haloalkane dehalogenases: from chemical waste to enantiopure building blocks.Utilizing natural diversity to evolve protein function: applications towards thermostability.High throughput screening of fungal endoglucanase activity in Escherichia coli Complex recombination patterns arising during geminivirus coinfections preserve and demarcate biologically important intra-genome interaction networks.Hypocrea jecorina CEL6A protein engineering.Random field model reveals structure of the protein recombinational landscape.Chimeric β-lactamases: global conservation of parental function and fast time-scale dynamics with increased slow motions Comparison of family 9 cellulases from mesophilic and thermophilic bacteria.Cellulases from thermophilic fungi: recent insights and biotechnological potential.Discriminating between stabilizing and destabilizing protein design mutations via recombination and simulation.Computational investigation of glycosylation effects on a family 1 carbohydrate-binding module.Exploring the Mechanism Responsible for Cellulase Thermostability by Structure-Guided Recombination.Structure-guided SCHEMA recombination generates diverse chimeric channelrhodopsins Molecular tools for chemical biotechnology.Processive and nonprocessive cellulases for biofuel production--lessons from bacterial genomes and structural analysis.Stabilizing biocatalysts.Recent advances in rational approaches for enzyme engineering.Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently.Improving the activity of Trichoderma reesei cel7B through stabilizing the transition state.Exploiting sequence and stability information for directing nanobody stability engineering.Efficient screening of fungal cellobiohydrolase class I enzymes for thermostabilizing sequence blocks by SCHEMA structure-guided recombination.Increasing protein stability: importance of DeltaC(p) and the denatured state.Crystal structure of a family 6 cellobiohydrolase from the basidiomycete Phanerochaete chrysosporium A thermophilic cellulase complex from Phialophora sp. G5 showing high capacity in cellulose hydrolysis.Highly thermostable fungal cellobiohydrolase I (Cel7A) engineered using predictive methods.Engineered thermostable fungal cellulases exhibit efficient synergistic cellulose hydrolysis at elevated temperatures.Removal of the free cysteine residue reduces irreversible thermal inactivation of feruloyl esterase: evidence from circular dichroism and fluorescence spectra.Biochemie 2009

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P2860

SCHEMA recombination of a fungal cellulase uncovers a single mutation that contributes markedly to stability

http://www.wikidata.org/entity/Q24648550

description

2009 nî lūn-bûn

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2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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SCHEMA recombination of a fung ...... tributes markedly to stability

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SCHEMA recombination of a fung ...... tributes markedly to stability

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SCHEMA recombination of a fung ...... tributes markedly to stability

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SCHEMA recombination of a fung ...... tributes markedly to stability

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SCHEMA recombination of a fung ...... tributes markedly to stability

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SCHEMA recombination of a fung ...... tributes markedly to stability

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prefLabel

SCHEMA recombination of a fung ...... tributes markedly to stability

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SCHEMA recombination of a fung ...... tributes markedly to stability

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SCHEMA recombination of a fung ...... tributes markedly to stability

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JBC.C109.034058

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Journal of Biological Chemistry

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SCHEMA recombination of a fung ...... tributes markedly to stability

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P2093

Alan Villalobos

http://www.w3.org/2001/XMLSchema#string

Arvind Kannan

http://www.w3.org/2001/XMLSchema#string

Jeremy Minshull

http://www.w3.org/2001/XMLSchema#string

Kevin Boulware

http://www.w3.org/2001/XMLSchema#string

Matthew A Smith

http://www.w3.org/2001/XMLSchema#string

Pete Heinzelman

http://www.w3.org/2001/XMLSchema#string

Sridhar Govindarajan

http://www.w3.org/2001/XMLSchema#string

Xinlin Yu

http://www.w3.org/2001/XMLSchema#string

P2860

Structure-guided recombination creates an artificial family of cytochromes P450.

A family of thermostable fungal cellulases created by structure-guided recombination

Distortion of a cellobio-derived isofagomine highlights the potential conformational itinerary of inverting beta-glucosidases

The active site of Trichoderma reesei cellobiohydrolase II: the role of tyrosine 169

Potential and utilization of thermophiles and thermostable enzymes in biorefining

Evolutionarily conserved pathways of energetic connectivity in protein families

Asparagine and glutamine: using hydrogen atom contacts in the choice of side-chain amide orientation

SHARPEN-systematic hierarchical algorithms for rotamers and proteins on an extended network.

Site-directed protein recombination as a shortest-path problem.

A diverse family of thermostable cytochrome P450s created by recombination of stabilizing fragments.

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26229-33

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scholarly article

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10.1074/JBC.C109.034058

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P433

39

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284

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Christopher D Snow

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2009-09-25T00:00:00Z

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19625252

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2785310

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