Identification of ALK as a major familial neuroblastoma predisposition gene - sprookjes - yvandenbroek - TriplyDB

Identification of ALK as a major familial neuroblastoma predisposition gene

Identification of ALK as a major familial neuroblastoma predisposition gene

http://www.wikidata.org/entity/Q24655923

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SK-N-SH CHLA-119 CHLA-150 CHLA-51 CHLA-79 CHP-134 CHP-212 CHP-901 IMR-5 Kelly LA-N-1 LA-N-5 LA-N-6 NB-1643 NB-1771 NB-EbC1 NB-SD NBL-S NGP NLF NMB SK-N-AS SK-N-BE(2)-C SK-N-DZ SK-N-FI SMS-KCN SMS-SAN

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COPS: a sensitive and accurate tool for detecting somatic Copy Number Alterations using short-read sequence data from paired samples Anaplastic lymphoma kinase-positive large B-cell lymphoma: an underrecognized aggressive lymphoma ALK mutations confer differential oncogenic activation and sensitivity to ALK inhibition therapy in neuroblastoma Anaplastic lymphoma kinase: signalling in development and disease Anaplastic thyroid cancers harbor novel oncogenic mutations of the ALK gene Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma Common variations in BARD1 influence susceptibility to high-risk neuroblastoma The role of the ALK receptor in cancer biology Translational development of difluoromethylornithine (DFMO) for the treatment of neuroblastoma Neuroblastoma: oncogenic mechanisms and therapeutic exploitation of necroptosis ALK and ROS1 as targeted therapy paradigms and clinical implications to overcome crizotinib resistance Preclinical Childhood Sarcoma Models: Drug Efficacy Biomarker Identification and Validation Amplification of Cellular Oncogenes in Solid Tumors Chemoresistance, cancer stem cells, and miRNA influences: the case for neuroblastoma Emerging importance of ALK in neuroblastoma Epigenetic deregulation of microRNAs in rhabdomyosarcoma and neuroblastoma and translational perspectives Involvement of midkine in neuroblastoma tumourigenesis ALK kinase domain mutations in primary anaplastic large cell lymphoma: consequences on NPM-ALK activity and sensitivity to tyrosine kinase inhibitors Neuroblastoma tyrosine kinase signaling networks involve FYN and LYN in endosomes and lipid rafts Time-lapse imaging of neuroblastoma cells to determine cell fate upon gene knockdown Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain CDK Inhibitors Roscovitine and CR8 Trigger Mcl-1 Down-Regulation and Apoptotic Cell Death in Neuroblastoma Cells The R1275Q Neuroblastoma Mutant and Certain ATP-competitive Inhibitors Stabilize Alternative Activation Loop Conformations of Anaplastic Lymphoma Kinase Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer.ALK mutations conferring differential resistance to structurally diverse ALK inhibitors.Differential inhibitor sensitivity of anaplastic lymphoma kinase variants found in neuroblastoma.Safety and activity of crizotinib for paediatric patients with refractory solid tumours or anaplastic large-cell lymphoma: a Children's Oncology Group phase 1 consortium study.Two novel ALK mutations mediate acquired resistance to the next-generation ALK inhibitor alectinib The ALK/ROS1 Inhibitor PF-06463922 Overcomes Primary Resistance to Crizotinib in ALK-Driven Neuroblastoma.Novel ALK inhibitor AZD3463 inhibits neuroblastoma growth by overcoming crizotinib resistance and inducing apoptosis.Brigatinib, an anaplastic lymphoma kinase inhibitor, abrogates activity and growth in ALK-positive neuroblastoma cells, Drosophila and mice.The zebrafish as a model for studying neuroblastoma Identifying Cancer Driver Genes Using Replication-Incompetent Retroviral Vectors Focal DNA copy number changes in neuroblastoma target MYCN regulated genes FAM150A and FAM150B are activating ligands for anaplastic lymphoma kinase Inhibitors of the anaplastic lymphoma kinase Molecular pathogenesis of peripheral neuroblastic tumors Renal cell carcinoma with novel VCL-ALK fusion: new representative of ALK-associated tumor spectrum ALK and NSCLC: Targeted therapy with ALK inhibitors Internalization and down-regulation of the ALK receptor in neuroblastoma cell lines upon monoclonal antibodies treatment

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P2860

Identification of ALK as a major familial neuroblastoma predisposition gene

http://www.wikidata.org/entity/Q24655923

description

2008 nî lūn-bûn

@nan

2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

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2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

Identification of ALK as a major familial neuroblastoma predisposition gene

@ast

Identification of ALK as a major familial neuroblastoma predisposition gene

@en

Identification of ALK as a major familial neuroblastoma predisposition gene

@nl

type

label

Identification of ALK as a major familial neuroblastoma predisposition gene

@ast

Identification of ALK as a major familial neuroblastoma predisposition gene

@en

Identification of ALK as a major familial neuroblastoma predisposition gene

@nl

prefLabel

Identification of ALK as a major familial neuroblastoma predisposition gene

@ast

Identification of ALK as a major familial neuroblastoma predisposition gene

@en

Identification of ALK as a major familial neuroblastoma predisposition gene

@nl

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P1476

Identification of ALK as a major familial neuroblastoma predisposition gene

@en

P2093

Ali Torkamani

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Andrew Wood

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Cuiping Hou

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Edward F Attiyeh

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Eric Rappaport

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Garrett M Brodeur

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Gian P Tonini

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Jill E Lynch

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John M Maris

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Kristina A Cole

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P2860

Polyalanine expansion and frameshift mutations of the paired-like homeobox gene PHOX2B in congenital central hypoventilation syndrome

Chromosome 6p22 locus associated with clinically aggressive neuroblastoma

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer.

Genomic alterations of anaplastic lymphoma kinase may sensitize tumors to anaplastic lymphoma kinase inhibitors.

Merlin--rapid analysis of dense genetic maps using sparse gene flow trees

Expression and functional analysis of the anaplastic lymphoma kinase (ALK) gene in tumor cell lines

Activation of anaplastic lymphoma kinase is responsible for hyperphosphorylation of ShcC in neuroblastoma cell lines

Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma

Chromosome localization in normal human cells and neuroblastomas of a gene related to c-myc

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930-5

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scholarly article

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3472627

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10.1038/NATURE07261

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P433

7215

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455

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Marcella Devoto

Hakon Hakonarson

Geneviève Laureys

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2008-10-16T00:00:00Z

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23191142

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1023388082

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18724359

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2672043

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