Role of nitrosative stress and peroxynitrite in the pathogenesis of diabetic complications. Emerging new therapeutical strategies - sprookjes - yvandenbroek - TriplyDB

Role of nitrosative stress and peroxynitrite in the pathogenesis of diabetic complications. Emerging new therapeutical strategies

Role of nitrosative stress and peroxynitrite in the pathogenesis of diabetic complications. Emerging new therapeutical strategies

http://www.wikidata.org/entity/Q24656109

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Extracellular PBEF/NAMPT/visfatin activates pro-inflammatory signalling in human vascular smooth muscle cells through nicotinamide phosphoribosyltransferase activity Biomarkers of Psychological Stress in Health Disparities Research Nitric oxide and peroxynitrite in health and disease Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol How exercise may amend metabolic disturbances in diabetic cardiomyopathy Interplay of oxidative, nitrosative/nitrative stress, inflammation, cell death and autophagy in diabetic cardiomyopathy Pathophysiological Role of Peroxynitrite Induced DNA Damage in Human Diseases: A Special Focus on Poly(ADP-ribose) Polymerase (PARP)Effect of telmisartan in experimentally induced diabetetes mellitus in rats Increased Oxidative and Nitrative Stress Accelerates Aging of the Retinal Vasculature in the Diabetic Retina Na+/H+-exchanger-1 inhibition counteracts diabetic cataract formation and retinal oxidative-nitrative stress and apoptosis Oxidative Stress-Related Mechanisms and Antioxidant Therapy in Diabetic Retinopathy Linoleic acid-induced mitochondrial Ca(2+) efflux causes peroxynitrite generation and protein nitrotyrosylation.Interplay between Akt and p38 MAPK pathways in the regulation of renal tubular cell apoptosis associated with diabetic nephropathy Neuroinflammation and oxidative stress in diabetic neuropathy: futuristic strategies based on these targets.Xanthine oxidase inhibitor allopurinol attenuates the development of diabetic cardiomyopathy.Optimal conditions of LDR to protect the kidney from diabetes: exposure to 12.5 mGy X-rays for 8 weeks efficiently protects the kidney from diabetes NF-kappaB-induced oxidative stress contributes to mitochondrial and cardiac dysfunction in type II diabetes.S-nitrosoglutathione reductase deficiency-induced S-nitrosylation results in neuromuscular dysfunction.Phytochemical studies of the phenolic substances in Aster glehni extract and its sedative and anticonvulsant activity.Peroxynitrite and protein nitration in the pathogenesis of diabetic peripheral neuropathy.Peroxynitrite-driven mechanisms in diabetes and insulin resistance - the latest advances The role of arginase I in diabetes-induced retinal vascular dysfunction in mouse and rat models of diabetes.Nitrosylated proteins in monocytes as a new marker of oxidative-nitrosative stress in diabetic subjects with macroangiopathy.Effect of periodontal treatment on adipokines in type 2 diabetes.Activation of the poly(ADP-ribose) polymerase pathway in human heart failure.Regulation of Inducible Nitric Oxide Synthase (iNOS) and its Potential Role in Insulin Resistance, Diabetes and Heart Failure Cardiac NO signalling in the metabolic syndrome.Simultaneous quantification and validation of new peroxynitrite scavengers from Artemisia iwayomogi.Triglyceride, nonesterified fatty acids, and prediabetic neuropathy: role for oxidative-nitrosative stress.Oral inflammatory diseases and systemic inflammation: role of the macrophage.Nitrosative stress and pharmacological modulation of heart failure.Response of the human myocardium to ischemic injury and preconditioning: The role of cardiac and comorbid conditions, medical treatment, and basal redox status Role of poly(ADP-ribose) polymerase-1 activation in the pathogenesis of diabetic complications: endothelial dysfunction, as a common underlying theme.Role of peroxynitrite in the pathogenesis of cardiovascular complications of diabetes.Role of poly(ADP-ribose) polymerase 1 (PARP-1) in cardiovascular diseases: the therapeutic potential of PARP inhibitors A peroxynitrite decomposition catalyst counteracts sensory neuropathy in streptozotocin-diabetic mice.Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption.Vascular dysfunction in aging: potential effects of resveratrol, an anti-inflammatory phytoestrogen.Peroxynitrite is a major trigger of cardiomyocyte apoptosis in vitro and in vivo.Sodium-glucose cotransporter inhibition prevents oxidative stress in the kidney of diabetic rats.

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Role of nitrosative stress and peroxynitrite in the pathogenesis of diabetic complications. Emerging new therapeutical strategies

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Csaba Szabó

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Irina G Obrosova

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Jon G Mabley

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Pál Pacher

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P2860

Biochemistry and molecular cell biology of diabetic complications

Effect of M40403 treatment of diabetic rats on endoneurial blood flow, motor nerve conduction velocity and vascular function of epineurial arterioles of the sciatic nerve

A hydroxyl radical-like species oxidizes cynomolgus monkey artery wall proteins in early diabetic vascular disease

Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly

Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

Microvascular and macrovascular reactivity is reduced in subjects at risk for type 2 diabetes.

The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases.

Protein tyrosine nitration in the mitochondria from diabetic mouse heart. Implications to dysfunctional mitochondria in diabetes.

Cardiac peroxynitrite formation and left ventricular dysfunction following doxorubicin treatment in mice.

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