Nedd4-2 isoforms ubiquitinate individual epithelial sodium channel subunits and reduce surface expression and function of the epithelial sodium channel
about
Selective targeting of activating and inhibitory Smads by distinct WWP2 ubiquitin ligase isoforms differentially modulates TGFβ signalling and EMTRespiratory distress and perinatal lethality in Nedd4-2-deficient miceNedd4-2 interacts with occludin to inhibit tight junction formation and enhance paracellular conductance in collecting duct epitheliaData integration in physiology using Bayes' rule and minimum Bayes' factors: deubiquitylating enzymes in the renal collecting duct.Cholera toxin enhances Na(+) absorption across MCF10A human mammary epithelia.Lysine 63-linked polyubiquitination of the dopamine transporter requires WW3 and WW4 domains of Nedd4-2 and UBE2D ubiquitin-conjugating enzymes.Endothelin-1 inhibits the epithelial Na+ channel through betaPix/14-3-3/Nedd4-2.Enhanced expression of epithelial sodium channels causes salt-induced hypertension in mice through inhibition of the α2-isoform of Na+, K+-ATPaseSalt-induced hypertension in a mouse model of Liddle syndrome is mediated by epithelial sodium channels in the brainNedd4-2 but not Nedd4-1 is critical for protein kinase C-regulated ubiquitination, expression, and transport activity of human organic anion transporter 1The activity of the epithelial sodium channels is regulated by caveolin-1 via a Nedd4-2-dependent mechanism.An Essential Role of Nedd4-2 in the Ubiquitination, Expression, and Function of Organic Anion Transporter-3.ENaC activity is increased in isolated, split-open cortical collecting ducts from protein kinase Cα knockout mice.How ubiquitination regulates the TGF-β signalling pathway: new insights and new players: new isoforms of ubiquitin-activating enzymes in the E1-E3 families join the game.Blood pressure regulation via the epithelial sodium channel: from gene to kidney and beyond.A regulated NH2-terminal Sgk1 variant with enhanced function is expressed in the collecting duct.An evolutionarily conserved N-terminal Sgk1 variant with enhanced stability and improved function.AICAR activates AMPK and alters PIP2 association with the epithelial sodium channel ENaC to inhibit Na+ transport in H441 lung epithelial cells.
P2860
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P2860
Nedd4-2 isoforms ubiquitinate individual epithelial sodium channel subunits and reduce surface expression and function of the epithelial sodium channel
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Nedd4-2 isoforms ubiquitinate ...... the epithelial sodium channel
@ast
Nedd4-2 isoforms ubiquitinate ...... the epithelial sodium channel
@en
Nedd4-2 isoforms ubiquitinate ...... the epithelial sodium channel
@nl
type
label
Nedd4-2 isoforms ubiquitinate ...... the epithelial sodium channel
@ast
Nedd4-2 isoforms ubiquitinate ...... the epithelial sodium channel
@en
Nedd4-2 isoforms ubiquitinate ...... the epithelial sodium channel
@nl
prefLabel
Nedd4-2 isoforms ubiquitinate ...... the epithelial sodium channel
@ast
Nedd4-2 isoforms ubiquitinate ...... the epithelial sodium channel
@en
Nedd4-2 isoforms ubiquitinate ...... the epithelial sodium channel
@nl
P2860
P1476
Nedd4-2 isoforms ubiquitinate ...... the epithelial sodium channel
@en
P2093
Nandita S Raikwar
P2860
P304
P356
10.1152/AJPRENAL.00339.2007
P407
P577
2008-03-05T00:00:00Z