The protein kinase IKKepsilon regulates energy balance in obese mice - sprookjes - yvandenbroek - TriplyDB

The protein kinase IKKepsilon regulates energy balance in obese mice

The protein kinase IKKepsilon regulates energy balance in obese mice

http://www.wikidata.org/entity/Q24658201

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GPRC5B activates obesity-associated inflammatory signaling in adipocytes Emerging roles for the non-canonical IKKs in cancer Obesity-Driven Gut Microbiota Inflammatory Pathways to Metabolic Syndrome TCR signaling to NF-κB and mTORC1: Expanding roles of the CARMA1 complex Increased Energy Expenditure, Ucp1 Expression, and Resistance to Diet-induced Obesity in Mice Lacking Nuclear Factor-Erythroid-2-related Transcription Factor-2 (Nrf2)EBF2 determines and maintains brown adipocyte identity IKKε knockout prevents high fat diet induced arterial atherosclerosis and NF-κB signaling in mice Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis Mechanisms for insulin resistance: common threads and missing links The role of HTS in drug discovery at the University of Michigan.IKKβ links vascular inflammation to obesity and atherosclerosis A recurring problem with the analysis of energy expenditure in genetic models expressing lean and obese phenotypes Downregulation of the tumour suppressor p16INK4A contributes to the polarisation of human macrophages toward an adipose tissue macrophage (ATM)-like phenotype CREG1 heterozygous mice are susceptible to high fat diet-induced obesity and insulin resistance.Endogenous ω-3 polyunsaturated fatty acid production confers resistance to obesity, dyslipidemia, and diabetes in mice NF-κB-to-AP-1 switch: a mechanism regulating transition from endothelial barrier injury to repair in endotoxemic mice.Molecular imaging of transcriptional regulation during inflammation TLR4 and Insulin Resistance.Induction of IL-17A Precedes Development of Airway Hyperresponsiveness during Diet-Induced Obesity and Correlates with Complement Factor D Specification of the NF-kappaB transcriptional response by p65 phosphorylation and TNF-induced nuclear translocation of IKK epsilon.Adaptive thermogenesis in adipocytes: is beige the new brown?An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice A decade of progress in adipose tissue macrophage biology.An obligatory role of NF-κB in mediating bone marrow derived endothelial progenitor cell recruitment and proliferation following endotoxemic multiple organ injury in mice.Insulin resistance is associated with MCP1-mediated macrophage accumulation in skeletal muscle in mice and humans Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice.IL-4/STAT6 immune axis regulates peripheral nutrient metabolism and insulin sensitivity Current and upcoming pharmacotherapy for non-alcoholic fatty liver disease.Suppression of adipogenesis by pathogenic seipin mutant is associated with inflammatory response Hematopoietic IKBKE limits the chronicity of inflammasome priming and metaflammation.Inflammatory links between obesity and metabolic disease.Genetic defect in phospholipase Cδ1 protects mice from obesity by regulating thermogenesis and adipogenesis Sirtuin-1 regulation of mammalian metabolism A subcutaneous adipose tissue-liver signalling axis controls hepatic gluconeogenesis.A unique hybrid renal mononuclear phagocyte activation phenotype in murine systemic lupus erythematosus nephritis.Mice with null mutation of Ceacam I develop nonalcoholic steatohepatitis.Deficiency for costimulatory receptor 4-1BB protects against obesity-induced inflammation and metabolic disorders Transcriptional control and hormonal response of thermogenic fat.De Novo Reconstruction of Adipose Tissue Transcriptomes Reveals Long Non-coding RNA Regulators of Brown Adipocyte Development.Ablation of the transcriptional regulator Id1 enhances energy expenditure, increases insulin sensitivity, and protects against age and diet induced insulin resistance, and hepatosteatosis.

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P2860

The protein kinase IKKepsilon regulates energy balance in obese mice

http://www.wikidata.org/entity/Q24658201

description

2009 nî lūn-bûn

@nan

2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

The protein kinase IKKepsilon regulates energy balance in obese mice

@ast

The protein kinase IKKepsilon regulates energy balance in obese mice

@en

The protein kinase IKKepsilon regulates energy balance in obese mice

@nl

type

label

The protein kinase IKKepsilon regulates energy balance in obese mice

@ast

The protein kinase IKKepsilon regulates energy balance in obese mice

@en

The protein kinase IKKepsilon regulates energy balance in obese mice

@nl

prefLabel

The protein kinase IKKepsilon regulates energy balance in obese mice

@ast

The protein kinase IKKepsilon regulates energy balance in obese mice

@en

The protein kinase IKKepsilon regulates energy balance in obese mice

@nl

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J.CELL.2009.06.046

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The protein kinase IKKepsilon regulates energy balance in obese mice

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Dan Westcott

http://www.w3.org/2001/XMLSchema#string

Jennifer B Delproposto

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Jie Zhou

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Jing-Tyan Ma

http://www.w3.org/2001/XMLSchema#string

Jonathan Mowers

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Lynn M Geletka

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Merlijn Bazuine

http://www.w3.org/2001/XMLSchema#string

Nathan Qi

http://www.w3.org/2001/XMLSchema#string

Nicole M White

http://www.w3.org/2001/XMLSchema#string

Shian-Huey Chiang

http://www.w3.org/2001/XMLSchema#string

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Obesity, Inflammation, and Insulin Resistance

Inflammation, stress, and diabetes

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

Inflammation and metabolic disorders

Obesity is associated with macrophage accumulation in adipose tissue

Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta

New perspectives into the molecular pathogenesis and treatment of type 2 diabetes

JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity

Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity

Bone marrow-specific Cap gene deletion protects against high-fat diet-induced insulin resistance

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961-75

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10.1016/J.CELL.2009.06.046

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Alan R. Saltiel

Carey N. Lumeng

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2009-09-04T00:00:00Z

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26796370

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