Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10Cloning and functional characterization of related TC10 isoforms, a subfamily of Rho proteins involved in insulin-stimulated glucose transportA role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's diseaseCAP interacts with cytoskeletal proteins and regulates adhesion-mediated ERK activation and motilitySmall GTP-binding protein TC10 differentially regulates two distinct populations of filamentous actin in 3T3L1 adipocytes.APS facilitates c-Cbl tyrosine phosphorylation and GLUT4 translocation in response to insulin in 3T3-L1 adipocytesIn vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P.Insulin stimulates phosphatidylinositol 3-phosphate production via the activation of Rab5The protein kinase IKKepsilon regulates energy balance in obese micePhosphoinositides: Key modulators of energy metabolismStructural basis for recruitment of the adaptor protein APS to the activated insulin receptorThe exocyst complex is required for targeting of Glut4 to the plasma membrane by insulinNew perspectives into the molecular pathogenesis and treatment of type 2 diabetesBlockade of the MAP kinase pathway suppresses growth of colon tumors in vivoActivation of RalA is required for insulin-stimulated Glut4 trafficking to the plasma membrane via the exocyst and the motor protein Myo1cp75 neurotrophin receptor regulates glucose homeostasis and insulin sensitivityPTG, a protein phosphatase 1-binding protein with a role in glycogen metabolismA Ral GAP complex links PI 3-kinase/Akt signaling to RalA activation in insulin actionPD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivoActivation of glycogen synthase by insulin in 3T3-L1 adipocytes involves c-Cbl-associating protein (CAP)-dependent and CAP-independent signaling pathways.TC10 is regulated by caveolin in 3T3-L1 adipocytesAtypical protein kinase C (PKCzeta/lambda) is a convergent downstream target of the insulin-stimulated phosphatidylinositol 3-kinase and TC10 signaling pathwaysMGL1 promotes adipose tissue inflammation and insulin resistance by regulating 7/4hi monocytes in obesity.Identification of binding sites on protein targeting to glycogen for enzymes of glycogen metabolism.Metabolic crosstalk: molecular links between glycogen and lipid metabolism in obesity.An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in miceThe regulation of glycogen synthase by protein phosphatase 1 in 3T3-L1 adipocytes. Evidence for a potential role for DARPP-32 in insulin action.Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistanceMore TORC for the gluconeogenic engine.A Rab10:RalA G protein cascade regulates insulin-stimulated glucose uptake in adipocytes.A pericellular collagenase directs the 3-dimensional development of white adipose tissue.Insulin signaling pathways in time and space.Insulin-stimulated Interaction between insulin receptor substrate 1 and p85alpha and activation of protein kinase B/Akt require Rab5.Protein-tyrosine-phosphatase SHPTP2 is a required positive effector for insulin downstream signaling.Inflammatory links between obesity and metabolic disease.A subcutaneous adipose tissue-liver signalling axis controls hepatic gluconeogenesis.SRA regulates adipogenesis by modulating p38/JNK phosphorylation and stimulating insulin receptor gene expression and downstream signaling.Zinc finger protein 407 (ZFP407) regulates insulin-stimulated glucose uptake and glucose transporter 4 (Glut4) mRNACircadian metabolic regulation through crosstalk between casein kinase 1δ and transcriptional coactivator PGC-1α.Putting the brakes on insulin signaling.
P50
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P50
description
hulumtues
@sq
onderzoeker
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researcher
@en
հետազոտող
@hy
name
Alan R Saltiel
@nl
Alan R Saltiel
@sl
Alan R. Saltiel
@en
Alan R. Saltiel
@es
type
label
Alan R Saltiel
@nl
Alan R Saltiel
@sl
Alan R. Saltiel
@en
Alan R. Saltiel
@es
altLabel
Alan R Saltiel
@en
prefLabel
Alan R Saltiel
@nl
Alan R Saltiel
@sl
Alan R. Saltiel
@en
Alan R. Saltiel
@es
P106
P1153
35464821500
P21
P31
P496
0000-0002-9726-9828