Regulation of cytokine-independent survival kinase (CISK) by the Phox homology domain and phosphoinositides
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Determinants of the endosomal localization of sorting nexin 1.CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4Second AKT: the rise of SGK in cancer signallingEvidence for a role of SNX16 in regulating traffic between the early and later endosomal compartmentsSLIC-1/sorting nexin 20: a novel sorting nexin that directs subcellular distribution of PSGL-1The Phox homology (PX) domain, a new player in phosphoinositide signallingImportin-alpha mediates the regulated nuclear targeting of serum- and glucocorticoid-inducible protein kinase (Sgk) by recognition of a nuclear localization signal in the kinase central domainSgk3 links growth factor signaling to maintenance of progenitor cells in the hair follicle.Crystal structure of the yeast Phox homology (PX) domain protein Grd19p complexed to phosphatidylinositol-3-phosphateFull-length p40phox structure suggests a basis for regulation mechanism of its membrane bindingMolecular mechanism of membrane docking by the Vam7p PX domain.All phox homology (PX) domains from Saccharomyces cerevisiae specifically recognize phosphatidylinositol 3-phosphate.The adaptor protein fish associates with members of the ADAMs family and localizes to podosomes of Src-transformed cellsPeroxisomal targeting as a tool for assaying potein-protein interactions in the living cell: cytokine-independent survival kinase (CISK) binds PDK-1 in vivo in a phosphorylation-dependent mannerDysregulated ryanodine receptors mediate cellular toxicity: restoration of normal phenotype by FKBP12.6The phox homology (PX) domain-dependent, 3-phosphoinositide-mediated association of sorting nexin-1 with an early sorting endosomal compartment is required for its ability to regulate epidermal growth factor receptor degradationUbiquitin modification of serum and glucocorticoid-induced protein kinase-1 (SGK-1)Munc-18-1 inhibits phospholipase D activity by direct interaction in an epidermal growth factor-reversible manner.Crystal structure of designed PX domain from cytokine-independent survival kinase and implications on evolution-based protein engineering.Regulation of NADPH oxidase in vascular endothelium: the role of phospholipases, protein kinases, and cytoskeletal proteins.Acquisition of unprecedented phosphatidylinositol 3,5-bisphosphate rise in hyperosmotically stressed 3T3-L1 adipocytes, mediated by ArPIKfyve-PIKfyve pathway.SGK3 mediates INPP4B-dependent PI3K signaling in breast cancerSGK3 is an estrogen-inducible kinase promoting estrogen-mediated survival of breast cancer cells.The critical roles of serum/glucocorticoid-regulated kinase 3 (SGK3) in the hair follicle morphogenesis and homeostasis: the allelic difference provides novel insights into hair follicle biology.Concerted roles of SGK1 and the Na+/H+ exchanger regulatory factor 2 (NHERF2) in regulation of NHE3.Serum- and glucocorticoid-induced kinase 3 in recycling endosomes mediates acute activation of Na+/H+ exchanger NHE3 by glucocorticoids.SGK3 (CISK) may induce tumor angiogenesis (Hypothesis).Multiple translational isoforms give functional specificity to serum- and glucocorticoid-induced kinase 1.A brain-specific SGK1 splice isoform regulates expression of ASIC1 in neurons.Emerging roles of phosphatidylinositol 3-monophosphate as a dynamic lipid second messenger.Mechanistic similarities in docking of the FYVE and PX domains to phosphatidylinositol 3-phosphate containing membranes.SGK3 is associated with estrogen receptor expression in breast cancer.Blunted IgE-mediated activation of mast cells in mice lacking the serum- and glucocorticoid-inducible kinase SGK3Identification of Flightless-I as a substrate of the cytokine-independent survival kinase CISK.Akt2 and SGK3 are both determinants of postnatal hair follicle development.Targeted disruption of the protein kinase SGK3/CISK impairs postnatal hair follicle development.Coordinated regulation of serum- and glucocorticoid-inducible kinase 3 by a C-terminal hydrophobic motif and Hsp90-Cdc37 chaperone complexAKT-independent PI3-K signaling in cancer - emerging role for SGK3.Novel mechanism of miRNA-365-regulated trophoblast apoptosis in recurrent miscarriageDevelopment of a small-molecule serum- and glucocorticoid-regulated kinase-1 antagonist and its evaluation as a prostate cancer therapeutic.
P2860
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P2860
Regulation of cytokine-independent survival kinase (CISK) by the Phox homology domain and phosphoinositides
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Regulation of cytokine-indepen ...... y domain and phosphoinositides
@ast
Regulation of cytokine-indepen ...... y domain and phosphoinositides
@en
Regulation of cytokine-indepen ...... y domain and phosphoinositides
@nl
type
label
Regulation of cytokine-indepen ...... y domain and phosphoinositides
@ast
Regulation of cytokine-indepen ...... y domain and phosphoinositides
@en
Regulation of cytokine-indepen ...... y domain and phosphoinositides
@nl
prefLabel
Regulation of cytokine-indepen ...... y domain and phosphoinositides
@ast
Regulation of cytokine-indepen ...... y domain and phosphoinositides
@en
Regulation of cytokine-indepen ...... y domain and phosphoinositides
@nl
P2093
P2860
P356
P1476
Regulation of cytokine-indepen ...... y domain and phosphoinositides
@en
P2093
P2860
P304
P356
10.1083/JCB.200105089
P407
P577
2001-08-20T00:00:00Z