Differential roles of interleukin 15 mRNA isoforms generated by alternative splicing in immune responses in vivo
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DeltaBAFF, an alternate splice isoform that regulates receptor binding and biopresentation of the B cell survival cytokine, BAFFRole of interleukin 15 and interleukin 18 in inflammatory responseRegulating the immune system via IL-15 transpresentationDistinct peripheral blood RNA responses to Salmonella in pigs differing in Salmonella shedding levels: intersection of IFNG, TLR and miRNA pathwaysIL-15/IL-15Ralpha intracellular trafficking in human melanoma cells and signal transduction through the IL-15RalphaInterleukin-15 enhances innate and adaptive immune responses to blood-stage malaria infection in mice.Induction of Mycobacterium tuberculosis-specific primary and secondary T-cell responses in interleukin-15-deficient mice.IL-15 plays a major role in the persistence of Tax-specific CD8 cells in HAM/TSP patients.Qualitative differences between naïve and memory T cells.IL-7 regulates basal homeostatic proliferation of antiviral CD4+T cell memory.Soluble interleukin-15 complexes are generated in vivo by type I interferon dependent and independent pathwaysDysregulation of IL-15-mediated T-cell homeostasis in TGF-beta dominant-negative receptor transgenic mice.Comparative assessment of virulence of recombinant vaccinia viruses expressing IL-2 and IL-15 in immunodeficient mice.Interleukin-15 as an immune adjuvant to increase the efficacy of Mycobacterium bovis bacillus Calmette-Guérin vaccination.Widespread Shortening of 3' Untranslated Regions and Increased Exon Inclusion Are Evolutionarily Conserved Features of Innate Immune Responses to Infection.Putative alternative polyadenylation (APA) events in the early interaction of Salmonella enterica Typhimurium and human host cellsFatal leukemia in interleukin 15 transgenic mice follows early expansions in natural killer and memory phenotype CD8+ T cells.Misregulated posttranscriptional checkpoints: inflammation and tumorigenesisInterleukin (IL)-15R[alpha]-deficient natural killer cells survive in normal but not IL-15R[alpha]-deficient miceHomeostasis of memory T cells.Onset of natural killer cell lymphomas in transgenic mice carrying a truncated HMGI-C gene by the chronic stimulation of the IL-2 and IL-15 pathway.Generating super-shedders: co-infection increases bacterial load and egg production of a gastrointestinal helminth.IL-15 produced and trans-presented by DCs underlies homeostatic competition between CD8 and {gamma}{delta} T cells in vivoSafety and immunologic effects of IL-15 administration in nonhuman primates.Role of IL-15 and IL-21 in viral immunity: applications for vaccines and therapies.Trans-presentation: a novel mechanism regulating IL-15 delivery and responses.Interleukin and interleukin receptor diversity: role of alternative splicing.Homeostatic maintenance of T cells and natural killer cells.Lymphocyte-based model systems for allergy research: a historic overview.Thymic Stromal Lymphopoietin: To Cut a Long Story Short.Interleukin-6 up-regulates the expression of interleukin-15 is associated with MAPKs and PI3-K signaling pathways in the human keratinocyte cell line, HaCaT.Mice lacking interleukin-2 (IL-2)/IL-15 receptor beta chain are susceptible to infection with avirulent Salmonella enterica subsp. enterica serovar choleraesuis but mice lacking IL-2 are resistant.Interleukin 15-mediated induction of cytotoxic effector cells capable of eliminating Epstein-Barr virus-transformed/immortalized lymphocytes in culture.Overexpression of Interleukin-15 increases susceptibility to lipopolysaccharide-induced liver injury in mice primed with Mycobacterium bovis bacillus Calmette-Guerin.Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype CD8(+) T cells.Role of interleukin-15 and interleukin-18 in the secretion of sIL-6R and sgp130 by human neutrophils.IL-15 protects antigen-specific CD8+ T cell contraction after Mycobacterium bovis bacillus Calmette-Guérin infection.Out-sourcing for Trans-presentation: Assessing T Cell Intrinsic and Extrinsic IL-15 Expression with Il15 Gene Reporter Mice.Airway epithelial IL-15 transforms monocytes into dendritic cells.Expression profile of skin papillomas with high cancer risk displays a unique genetic signature that clusters with squamous cell carcinomas and predicts risk for malignant conversion.
P2860
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P2860
Differential roles of interleukin 15 mRNA isoforms generated by alternative splicing in immune responses in vivo
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2000 nî lūn-bûn
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2000 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2000 թվականի հունվարին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Differential roles of interleu ...... ng in immune responses in vivo
@ast
Differential roles of interleu ...... ng in immune responses in vivo
@en
Differential roles of interleu ...... ng in immune responses in vivo
@nl
type
label
Differential roles of interleu ...... ng in immune responses in vivo
@ast
Differential roles of interleu ...... ng in immune responses in vivo
@en
Differential roles of interleu ...... ng in immune responses in vivo
@nl
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Differential roles of interleu ...... ng in immune responses in vivo
@ast
Differential roles of interleu ...... ng in immune responses in vivo
@en
Differential roles of interleu ...... ng in immune responses in vivo
@nl
P2093
P2860
P3181
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P1476
Differential roles of interleu ...... ng in immune responses in vivo
@en
P2093
H Nishimura
H Tsunobuchi
T Matsuguchi
Y Yoshikai
P2860
P304
P3181
P356
10.1084/JEM.191.1.157
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P577
2000-01-01T00:00:00Z