Dysregulation of IL-15-mediated T-cell homeostasis in TGF-beta dominant-negative receptor transgenic mice.
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TGF-β: guardian of T cell functionTGF-β sensitivity restrains CD8+ T cell homeostatic proliferation by enforcing sensitivity to IL-7 and IL-15Hepatitis C virus (HCV) evades NKG2D-dependent NK cell responses through NS5A-mediated imbalance of inflammatory cytokines.Overcoming the hurdles in using mouse genetic models that block TGF-beta signaling.TGF-β signalling is required for CD4⁺ T cell homeostasis but dispensable for regulatory T cell function.A phase I/II study of chemotherapy followed by donor lymphocyte infusion plus interleukin-2 for relapsed acute leukemia after allogeneic hematopoietic cell transplantationEnhanced responses to tumor immunization following total body irradiation are time-dependentLymphodepletion followed by donor lymphocyte infusion (DLI) causes significantly more acute graft-versus-host disease than DLI aloneT cell immune reconstitution following lymphodepletion.Truncated form of TGF-βRII, but not its absence, induces memory CD8+ T cell expansion and lymphoproliferative disorder in mice.Immune reconstitution and implications for immunotherapy following haematopoietic stem cell transplantationNegative regulators in homeostasis of naïve peripheral T cells.Ovarian hormone level alterations during rat post-reproductive life-span influence CD8 + T-cell homeostasis.Negative effect of KIR alloreactivity in recipients of umbilical cord blood transplant depends on transplantation conditioning intensity.Systemic inhibition of transforming growth factor-beta in glioma-bearing mice improves the therapeutic efficacy of glioma-associated antigen peptide vaccinesTransforming growth factor β signaling controls activities of human intestinal CD8(+)T suppressor cells.Homeostatic expansion as a barrier to lymphocyte depletion strategies.The immune suppressive function of transforming growth factor-β (TGF-β) in human diseases.Impact of Human Mutant TGFβ1/Fc Protein on Memory and Regulatory T Cell Homeostasis Following Lymphodepletion in Nonhuman Primates.Fine-tuning innate and adaptive immune responses: another KLFhanger. Focus on "Krüppel-like factor KLF10 regulates transforming growth factor receptor II expression and TGF-β signaling in CD8+ T lymphocytes".
P2860
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P2860
Dysregulation of IL-15-mediated T-cell homeostasis in TGF-beta dominant-negative receptor transgenic mice.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Dysregulation of IL-15-mediate ...... tive receptor transgenic mice.
@ast
Dysregulation of IL-15-mediate ...... tive receptor transgenic mice.
@en
type
label
Dysregulation of IL-15-mediate ...... tive receptor transgenic mice.
@ast
Dysregulation of IL-15-mediate ...... tive receptor transgenic mice.
@en
prefLabel
Dysregulation of IL-15-mediate ...... tive receptor transgenic mice.
@ast
Dysregulation of IL-15-mediate ...... tive receptor transgenic mice.
@en
P2093
P2860
P1433
P1476
Dysregulation of IL-15-mediate ...... tive receptor transgenic mice.
@en
P2093
Crystal L Mackall
Frances T Hakim
Philip J Lucas
Ronald E Gress
Seong-Jin Kim
William G Telford
Yu-Waye Chu
P2860
P304
P356
10.1182/BLOOD-2006-05-025676
P407
P577
2006-06-20T00:00:00Z