Cytochrome P4502C9: an enzyme of major importance in human drug metabolism
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Role of cytochrome P450 in drug interactionsInhibition of cytochrome P450 (CYP450) isoforms by isoniazid: potent inhibition of CYP2C19 and CYP3AInfluence of CYP2C9 and CYP2C19 genetic polymorphisms on pharmacokinetics of gliclazide MR in Chinese subjectsChloramphenicol is a potent inhibitor of cytochrome P450 isoforms CYP2C19 and CYP3A4 in human liver microsomesIdentification of the human cytochromes P450 catalysing the rate-limiting pathways of gliclazide eliminationOxidation of celecoxib by polymorphic cytochrome P450 2C9 and alcohol dehydrogenaseStructural evidence: a single charged residue affects substrate binding in cytochrome P450 BM-3Pharmacogenomics of Drug Metabolizing Enzymes and Transporters: Relevance to Precision MedicinePharmacogenomics and drug response in cardiovascular disordersEstablishment of a transgenic cell line stably expressing human cytochrome P450 2C18 and identification of a CYP2C18 clone with exon 5 missingFrequency of cytochrome P450 CYP2C9 variants in a Turkish population and functional relevance for phenytoinIn vitro inhibition of the cytochrome P450 (CYP450) system by the antiplatelet drug ticlopidine: potent effect on CYP2C19 and CYP2D6A case of intolerance to warfarin dosing in an intermediate metabolizer of CYP2C9High-dimensional pharmacogenetic prediction of a continuous trait using machine learning techniques with application to warfarin dose prediction in African AmericansMolecular dynamics simulations: from structure function relationships to drug discovery.Structural features of cytochromes P450 and ligands that affect drug metabolism as revealed by X-ray crystallography and NMR.Comparative QSAR analyses of competitive CYP2C9 inhibitors using three-dimensional molecular descriptors.Individualized therapy for type 2 diabetes: clinical implications of pharmacogenetic data.Valerenic acid and Valeriana officinalis extracts delay onset of Pentylenetetrazole (PTZ)-Induced seizures in adult Danio rerio (Zebrafish)Pharmacogenomics of diuretic drugs: data on rare monogenic disorders and on polymorphisms and requirements for further research.Characterisation of CYP2C8, CYP2C9 and CYP2C19 polymorphisms in a Ghanaian population.Implications of cytochrome P450 2C9 polymorphism on warfarin metabolism and dosing.Summary of information on human CYP enzymes: human P450 metabolism data.Clinical application of transcriptional activators of bile salt transporters.Metabolism-based drug interactions involving oral azole antifungals in humans.Update: genetic polymorphism of drug metabolizing enzymes in humans.Influence of regular physical activity on warfarin dose and risk of hemorrhagic complications.The nuclear receptors constitutive active/androstane receptor and pregnane x receptor activate the Cyp2c55 gene in mouse liver.In vitro and in vivo assessment of CYP2C9-mediated herb-herb interaction of Euphorbiae Pekinensis Radix and Glycyrrhizae RadixPharmacogenetic diagnostics of cytochrome P450 polymorphisms in clinical drug development and in drug treatment.Warfarin dosing in patients with impaired kidney functionOral anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.A Proposal for an Individualized Pharmacogenetic-Guided Warfarin Dosage Regimen for Puerto Rican Patients Commencing Anticoagulation Therapy.Pharmacogenetics: an opportunity for a safer and more efficient pharmacotherapy.Assessment of drug-drug interactions: concepts and approaches.Clinical implications of drug interactions with coxibs.Intramolecular heme ligation of the cytochrome P450 2C9 R108H mutant demonstrates pronounced conformational flexibility of the B-C loop region: implications for substrate binding.Human drug metabolism and the cytochromes P450: application and relevance of in vitro models.Bench to bedside: Pharmacogenomics, adverse drug interactions, and the cytochrome P450 system.Drug-drug interactions in pharmacologic management of gastroparesis.
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P2860
Cytochrome P4502C9: an enzyme of major importance in human drug metabolism
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Cytochrome P4502C9: an enzyme of major importance in human drug metabolism
@ast
Cytochrome P4502C9: an enzyme of major importance in human drug metabolism
@en
Cytochrome P4502C9: an enzyme of major importance in human drug metabolism
@nl
type
label
Cytochrome P4502C9: an enzyme of major importance in human drug metabolism
@ast
Cytochrome P4502C9: an enzyme of major importance in human drug metabolism
@en
Cytochrome P4502C9: an enzyme of major importance in human drug metabolism
@nl
prefLabel
Cytochrome P4502C9: an enzyme of major importance in human drug metabolism
@ast
Cytochrome P4502C9: an enzyme of major importance in human drug metabolism
@en
Cytochrome P4502C9: an enzyme of major importance in human drug metabolism
@nl
P2860
P1476
Cytochrome P4502C9: an enzyme of major importance in human drug metabolism
@en
P2093
D J Birkett
J O Miners
P2860
P304
P356
10.1046/J.1365-2125.1998.00721.X
P407
P577
1998-06-01T00:00:00Z