Structural features of cytochromes P450 and ligands that affect drug metabolism as revealed by X-ray crystallography and NMR.
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Structural insights into aldosterone synthase substrate specificity and targeted inhibitionBiomarkers of susceptibility: state of the art and implications for occupational exposure to engineered nanomaterialsConformational Adaptation of Human Cytochrome P450 2B6 and Rabbit Cytochrome P450 2B4 Revealed upon Binding Multiple Amlodipine MoleculesStructures of Cytochrome P450 2B6 Bound to 4-Benzylpyridine and 4-(4-Nitrobenzyl)pyridine: Insight into Inhibitor Binding and Rearrangement of Active Site Side ChainsA Structural Snapshot of CYP2B4 in Complex with Paroxetine Provides Insights into Ligand Binding and Clusters of Conformational StatesStructural and Thermodynamic Basis of (+)-α-Pinene Binding to Human Cytochrome P450 2B6Cytochrome P450 17A1 Interactions with the FMN Domain of Its Reductase as Characterized by NMRPredictive models for cytochrome p450 isozymes based on quantitative high throughput screening dataComparison of in vitro metabolism of ticlopidine by human cytochrome P450 2B6 and rabbit cytochrome P450 2B4Size- and time-dependent alteration in metabolic activities of human hepatic cytochrome P450 isozymes by gold nanoparticles via microsomal coincubationsA large-scale allosteric transition in cytochrome P450 3A4 revealed by luminescence resonance energy transfer (LRET).Structure-Function Analysis of Mammalian CYP2B Enzymes Using 7-Substituted Coumarin Derivatives as Probes: Utility of Crystal Structures and Molecular Modeling in Understanding Xenobiotic MetabolismConformational Mobility in Cytochrome P450 3A4 Explored by Pressure-Perturbation EPR SpectroscopyPlasticity of CYP2B enzymes: structural and solution biophysical methods.Functional characterization of cytochromes P450 2B from the desert woodrat Neotoma lepida.Analysis of Cytochrome P450 Conserved Sequence Motifs between Helices E and H: Prediction of Critical Motifs and Residues in Enzyme Functions.Structure and function of cytochromes P450 2B: from mechanism-based inactivators to X-ray crystal structures and backLigand Access Channels in Cytochrome P450 Enzymes: A Review.Structure and Dynamics of Human Drug-Metabolizing Cytochrome P450 Enzymes
P2860
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P2860
Structural features of cytochromes P450 and ligands that affect drug metabolism as revealed by X-ray crystallography and NMR.
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Structural features of cytochr ...... X-ray crystallography and NMR.
@ast
Structural features of cytochr ...... X-ray crystallography and NMR.
@en
type
label
Structural features of cytochr ...... X-ray crystallography and NMR.
@ast
Structural features of cytochr ...... X-ray crystallography and NMR.
@en
prefLabel
Structural features of cytochr ...... X-ray crystallography and NMR.
@ast
Structural features of cytochr ...... X-ray crystallography and NMR.
@en
P2093
P2860
P356
P1476
Structural features of cytochr ...... X-ray crystallography and NMR.
@en
P2093
Arthur G Roberts
James R Halpert
Sean C Gay
P2860
P304
P356
10.4155/FMC.10.229
P577
2010-09-01T00:00:00Z