The accumulation of MMS-induced single strand breaks in G1 phase is recombinogenic in DNA polymerase beta defective mammalian cells
about
Methyl methanesulfonate (MMS) produces heat-labile DNA damage but no detectable in vivo DNA double-strand breaks.PARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibilityBase excision repair intermediates are mutagenic in mammalian cellsThe Werner syndrome protein operates in base excision repair and cooperates with DNA polymerase beta.A germline polymorphism of DNA polymerase beta induces genomic instability and cellular transformationGastrointestinal hyperplasia with altered expression of DNA polymerase beta.DNA breaks and chromosomal aberrations arise when replication meets base excision repair.Involvement of DNA polymerase β overexpression in the malignant transformation induced by benzo[a]pyrene.High risk of benzo[α]pyrene-induced lung cancer in E160D FEN1 mutant miceHuman base excision repair complex is physically associated to DNA replication and cell cycle regulatory proteinsX-rays induce distinct patterns of somatic mutation in fetal versus adult hematopoietic cells.Gastric cancer associated variant of DNA polymerase beta (Leu22Pro) promotes DNA replication associated double strand breaksMethylating agents and DNA repair responses: Methylated bases and sources of strand breaks.Minimal role of base excision repair in TET-induced global DNA demethylation in HEK293T cellsChemical-induced cancer incidence and underlying mechanisms in Fen1 mutant mice.The FEN1 L209P mutation interferes with long-patch base excision repair and induces cellular transformation.Targeting DNA Flap Endonuclease 1 to Impede Breast Cancer Progression.Low-fidelity compensatory backup alternative DNA repair pathways may unify current carcinogenesis theories.RNA sequencing provides insights into the toxicogenomic response of ZF4 cells to methyl methanesulfonate.The budding yeast protein Chl1p is required to preserve genome integrity upon DNA damage in S-phase.Abundance of BER-related proteins depends on cell proliferation status and the presence of DNA polymerase β.DNA single-strand break-induced DNA damage response causes heart failure.3-Methyladenine DNA glycosylase is important for cellular resistance to psoralen interstrand cross-links.Replication stress-induced endogenous DNA damage drives cellular senescence induced by a sub-lethal oxidative stress.Crosstalk between mismatch repair and base excision repair in human gastric cancer.From single-strand breaks to double-strand breaks during S-phase: a new mode of action of the Escherichia coli Cytolethal Distending Toxin.PAM-OBG: A monoamine oxidase B specific prodrug that inhibits MGMT and generates DNA interstrand crosslinks, potentiating temozolomide and chemoradiation therapy in intracranial glioblastoma.
P2860
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P2860
The accumulation of MMS-induced single strand breaks in G1 phase is recombinogenic in DNA polymerase beta defective mammalian cells
description
2005 nî lūn-bûn
@nan
2005 թուականին հրատարակուած գիտական յօդուած
@hyw
2005 թվականին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The accumulation of MMS-induce ...... beta defective mammalian cells
@ast
The accumulation of MMS-induce ...... beta defective mammalian cells
@en
The accumulation of MMS-induce ...... beta defective mammalian cells
@nl
type
label
The accumulation of MMS-induce ...... beta defective mammalian cells
@ast
The accumulation of MMS-induce ...... beta defective mammalian cells
@en
The accumulation of MMS-induce ...... beta defective mammalian cells
@nl
prefLabel
The accumulation of MMS-induce ...... beta defective mammalian cells
@ast
The accumulation of MMS-induce ...... beta defective mammalian cells
@en
The accumulation of MMS-induce ...... beta defective mammalian cells
@nl
P2093
P2860
P3181
P356
P1476
The accumulation of MMS-induce ...... beta defective mammalian cells
@en
P2093
Eugenia Dogliotti
Margherita Bignami
Maria Teresa Russo
P2860
P304
P3181
P356
10.1093/NAR/GKI168
P407
P577
2005-01-12T00:00:00Z