The prolyl isomerase Pin1 in breast development and cancer - sprookjes - yvandenbroek - TriplyDB

The prolyl isomerase Pin1 in breast development and cancer

The prolyl isomerase Pin1 in breast development and cancer

http://www.wikidata.org/entity/Q24795560

about

The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer Nuclear import of Pin1 is mediated by a novel sequence in the PPIase domain NF-kappaB: a multifaceted transcription factor regulated at several levels Suppression of Wnt signaling by the green tea compound (-)-epigallocatechin 3-gallate (EGCG) in invasive breast cancer cells. Requirement of the transcriptional repressor HBP1 Pin1: a molecular orchestrator in the heart.Molecular basis for an ancient partnership between prolyl isomerase Pin1 and phosphatase inhibitor-2 Phosphorylation of serine 147 of tis21/BTG2/pc3 by p-Erk1/2 induces Pin-1 binding in cytoplasm and cell death.Pin1 facilitates the phosphorylation-dependent ubiquitination of SF-1 to regulate gonadotropin beta-subunit gene transcription G protein-coupled receptor kinase 2 (GRK2) modulation and cell cycle progression The Ess1 prolyl isomerase: traffic cop of the RNA polymerase II transcription cycle.The functional promoter polymorphism (-842G>C) in the PIN1 gene is associated with decreased risk of breast cancer in non-Hispanic white women 55 years and younger.Pin1 regulates the dynamics of c-Myc DNA binding to facilitate target gene regulation and oncogenesis.Peptidylprolyl Isomerase Pin1 Directly Enhances the DNA Binding Functions of Estrogen Receptor α.Somatic sequence alterations in twenty-one genes selected by expression profile analysis of breast carcinomas Phospho-specific Smad3 signaling: impact on breast oncogenesis.Grb7 Protein Stability Modulated by Pin1 in Association with Cell Cycle Progression Prolyl isomerase Pin1 downregulates tumor suppressor RUNX3 in breast cancer.Degradation of the tumor suppressor PML by Pin1 contributes to the cancer phenotype of breast cancer MDA-MB-231 cells.Role of Pin1 protein in the pathogenesis of nonalcoholic steatohepatitis in a rodent model Pin1-mediated Modification Prolongs the Nuclear Retention of β-Catenin in Wnt3a-induced Osteoblast Differentiation.Molecular mechanisms of the phospho-dependent prolyl cis/trans isomerase Pin1.Secreted cyclophilin A, a peptidylprolyl cis-trans isomerase, mediates matrix assembly of hensin, a protein implicated in epithelial differentiation.Peptidylproline cis-trans-isomerase Pin1 interacts with human T-cell leukemia virus type 1 tax and modulates its activation of NF-kappaB Pin1 modulates ERα levels in breast cancer through inhibition of phosphorylation-dependent ubiquitination and degradation.Pin1 modulates p63α protein stability in regulation of cell survival, proliferation and tumor formation Peptidyl-prolyl cis-trans isomerase Pin1 in ageing, cancer and Alzheimer disease.The CTD code of RNA polymerase II: a structural view.MYC degradation The cellular peptidyl-prolyl cis/trans isomerase Pin1 regulates reactivation of Kaposi's sarcoma-associated herpesvirus from latency Pin1 promotes GR transactivation by enhancing recruitment to target genes.Functional polymorphisms in PIN1 promoter and esophageal carcinoma susceptibility in Chinese population.Increased expression of PIN1 gene in papillary thyroid carcinoma.The prolyl cis/trans isomerase cyclophilin 18 interacts with the tumor suppressor p53 and modifies its functions in cell cycle regulation and apoptosis.Activation of beta-catenin signaling in prostate cancer by peptidyl-prolyl isomerase Pin1-mediated abrogation of the androgen receptor-beta-catenin interaction.PML: An emerging tumor suppressor and a target with therapeutic potential.Polo-like kinase 1-mediated phosphorylation stabilizes Pin1 by inhibiting its ubiquitination in human cells.Sensitizing effect of juglone is mediated by down regulation of Notch1 signaling pathway in trastuzumab-resistant SKBR3 cells.

P2860

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P2860

The prolyl isomerase Pin1 in breast development and cancer

http://www.wikidata.org/entity/Q24795560

description

2003 nî lūn-bûn

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2003 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2003 թվականի հունվարին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

@zh-tw

2003年论文

@wuu

name

The prolyl isomerase Pin1 in breast development and cancer

@ast

The prolyl isomerase Pin1 in breast development and cancer

@en

The prolyl isomerase Pin1 in breast development and cancer

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type

label

The prolyl isomerase Pin1 in breast development and cancer

@ast

The prolyl isomerase Pin1 in breast development and cancer

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The prolyl isomerase Pin1 in breast development and cancer

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prefLabel

The prolyl isomerase Pin1 in breast development and cancer

@ast

The prolyl isomerase Pin1 in breast development and cancer

@en

The prolyl isomerase Pin1 in breast development and cancer

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Breast Cancer Research

P1476

The prolyl isomerase Pin1 in breast development and cancer

@en

P2093

Akihide Ryo

http://www.w3.org/2001/XMLSchema#string

Gerburg Wulf

http://www.w3.org/2001/XMLSchema#string

Kun Ping Lu

http://www.w3.org/2001/XMLSchema#string

Yih-Cherng Liou

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P2860

Function of WW domains as phosphoserine- or phosphothreonine-binding modules

The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein

The Hallmarks of Cancer

Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

The mitotic peptidyl-prolyl isomerase, Pin1, interacts with Cdc25 and Plx1

Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1.

Accumulation of rab4GTP in the cytoplasm and association with the peptidyl-prolyl isomerase pin1 during mitosis

The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins

Tyrosine kinase signalling in breast cancer: tyrosine kinase-mediated signal transduction in transgenic mouse models of human breast cancer.

P2888

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76-82

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scholarly article

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3397826

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10.1186/BCR572

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P433

2

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5

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2003-01-28T00:00:00Z

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10861839

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1042650060

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12631385

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animal structure

breast neoplasm

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154150

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