The unfolded protein response in neurodegenerative diseases: a neuropathological perspective
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Copper Homeostasis as a Therapeutic Target in Amyotrophic Lateral Sclerosis with SOD1 MutationsTargeting New Candidate Genes by Small Molecules Approaching Neurodegenerative DiseasesUnfolded Protein Response and Macroautophagy in Alzheimer's, Parkinson's and Prion DiseasesSen1, the homolog of human Senataxin, is critical for cell survival through regulation of redox homeostasis, mitochondrial function, and the TOR pathway in Saccharomyces cerevisiaeMitofusin-mediated ER stress triggers neurodegeneration in pink1/parkin models of Parkinson's diseaseRoles of tau protein in health and disease.Role of Endoplasmic Reticulum Stress in Learning and Memory Impairment and Alzheimer's Disease-Like Neuropathology in the PS19 and APPSwe Mouse Models of Tauopathy and Amyloidosis.Involvement of Endoplasmic Reticulum Stress in TULP1 Induced Retinal Degeneration.PERK inhibition prevents tau-mediated neurodegeneration in a mouse model of frontotemporal dementia.Protective Effect of Enalapril against Methionine-Enriched Diet-Induced Hypertension: Role of Endoplasmic Reticulum and Oxidative Stress.NetDecoder: a network biology platform that decodes context-specific biological networks and gene activities.Activation of the unfolded protein response and granulovacuolar degeneration are not common features of human prion pathology.Tauroursodeoxycholic bile acid arrests axonal degeneration by inhibiting the unfolded protein response in X-linked adrenoleukodystrophy.New insights into the unfolded protein response in stem cells.Zika Virus as an Emerging Neuropathogen: Mechanisms of Neurovirulence and Neuro-Immune Interactions.ER stress and the unfolded protein response in neurodegeneration.Granulovacuolar degeneration: a neurodegenerative change that accompanies tau pathology.Protein kinase R(PKR)-like endoplasmic reticulum kinase (PERK) inhibitors: a patent review (2010-2015).The entangled ER-mitochondrial axis as a potential therapeutic strategy in neurodegeneration: A tangled duo unchained.Thiamine Deficiency and Neurodegeneration: the Interplay Among Oxidative Stress, Endoplasmic Reticulum Stress, and Autophagy.Cellular Regulation of Amyloid Formation in Aging and Disease.Modulation of AβPP and GSK3β by Endoplasmic Reticulum Stress and Involvement in Alzheimer's Disease.Endoplasmic reticulum proteostasis impairment in agingFine-tuning PERK signaling for neuroprotection.The Endoplasmic Reticulum Unfolded Protein Response in Neurodegenerative Disorders and Its Potential Therapeutic SignificanceTranscriptomic Analyses Reveal Differential Gene Expression of Immune and Cell Death Pathways in the Brains of Mice Infected with West Nile Virus and Chikungunya Virus.ER Stress and Neurodegenerative Disease: A Cause or Effect Relationship?Fine-Tuning ER Stress Signal Transducers to Treat Amyotrophic Lateral Sclerosis.Drug repurposing to target proteostasis and prevent neurodegeneration: accelerating translational efforts.IRE1 signaling exacerbates Alzheimer's disease pathogenesis.Bidirectional interplay of HSF1 degradation and UPR activation promotes tau hyperphosphorylation.Chronically stressed or stress-preconditioned neurons fail to maintain stress granule assembly.Interplay of Energetics and ER Stress Exacerbates Alzheimer's Amyloid-β (Aβ) Toxicity in Yeast.Inhibition of the integrated stress response reverses cognitive deficits after traumatic brain injuryCommentary: Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models.Activation of TGF-β signaling induces cell death via the unfolded protein response in Fuchs endothelial corneal dystrophy.Proteostasis disturbance in amyotrophic lateral sclerosis.Mitochondrial dysfunction induces dendritic loss via eIF2α phosphorylationPKR involvement in Alzheimer's diseaseRegulated Ire1-dependent mRNA decay requires no-go mRNA degradation to maintain endoplasmic reticulum homeostasis in S. pombe.
P2860
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P2860
The unfolded protein response in neurodegenerative diseases: a neuropathological perspective
description
2015 nî lūn-bûn
@nan
2015 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
The unfolded protein response ...... neuropathological perspective
@ast
The unfolded protein response ...... neuropathological perspective
@en
The unfolded protein response ...... neuropathological perspective
@nl
type
label
The unfolded protein response ...... neuropathological perspective
@ast
The unfolded protein response ...... neuropathological perspective
@en
The unfolded protein response ...... neuropathological perspective
@nl
prefLabel
The unfolded protein response ...... neuropathological perspective
@ast
The unfolded protein response ...... neuropathological perspective
@en
The unfolded protein response ...... neuropathological perspective
@nl
P2860
P921
P3181
P1476
The unfolded protein response ...... neuropathological perspective
@en
P2093
Jeroen J M Hoozemans
Wiep Scheper
P2860
P2888
P304
P3181
P356
10.1007/S00401-015-1462-8
P407
P5008
P577
2015-07-26T00:00:00Z
P5875
P6179
1027225338