about
A cytoplasmic NF-κB interacting long noncoding RNA blocks IκB phosphorylation and suppresses breast cancer metastasisAnti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasomeThe IKK inhibitor Bay 11-7082 induces cell death independent from inhibition of activation of NFκB transcription factors.BAY 11-7082 is a broad-spectrum inhibitor with anti-inflammatory activity against multiple targets.The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system.BAY 11-7082, a nuclear factor-κB inhibitor, induces apoptosis and S phase arrest in gastric cancer cells.The anti-inflammatory compound BAY-11-7082 is a potent inhibitor of protein tyrosine phosphatases.Bay 11-7082 inhibits transcription factor NF-kappaB and induces apoptosis of HTLV-I-infected T-cell lines and primary adult T-cell leukemia cells.BAY 11-7082 induces cell death through NF-kappaB-independent mechanisms in the Ewing's sarcoma family of tumours.Enhancement of TPA-induced growth inhibition and apoptosis in myeloid leukemia cells by BAY 11-7082, an NF-kappaB inhibitor.IKK inhibitor bay 11-7082 induces necroptotic cell death in precursor-B acute lymphoblastic leukaemic blasts.A noble function of BAY 11-7082: Inhibition of platelet aggregation mediated by an elevated cAMP-induced VASP, and decreased ERK2/JNK1 phosphorylations.The inhibitor of I kappa B alpha phosphorylation BAY 11-7082 prevents NMDA neurotoxicity in mouse hippocampal slices.The NFĸB pathway inhibitors Bay 11-7082 and parthenolide induce programmed cell death in anucleated Erythrocytes.BAY 11-7082 ameliorates diabetic nephropathy by attenuating hyperglycemia-mediated oxidative stress and renal inflammation via NF-κB pathwaySuppression of NF-κB and NF-κB regulated oxidative stress and neuroinflammation by BAY 11-7082 (IκB phosphorylation inhibitor) in experimental diabetic neuropathyAlpha-Tocopherol and BAY 11-7082 Reduce Vascular Cell Adhesion Molecule in Human Aortic Endothelial Cells
P921
Q24322334-F5E2CA9E-F9A6-4C79-988F-35F00F15B766Q33744674-29880BFC-3BC6-4285-8BA2-8E39CF095A00Q34634953-EE3889AA-C903-41B3-A42D-10C4B19D43A1Q36055896-1C36FBC8-2CE5-4BC9-80AD-B972848053AFQ36936317-B9FFA184-D56B-4EA1-9E3A-750A50416C48Q39127080-3E5C0A83-E624-4BF9-BE13-3B7E69718E5EQ39167879-D4CC2942-0B65-4FFE-91CE-2F2482F3BF2FQ39269067-F78C06B5-D01C-4FFC-8E45-4E284B38B853Q39983431-ED3AC4FC-EF17-4853-A404-776405FE5F9DQ40377420-7B2911B8-DC95-4D74-8D0D-D6545BBB33D2Q43230774-5AEC9304-BFA1-43CD-980E-5E5B3ADBDFF6Q43242551-5913CAC9-C577-4036-B4D1-AA6C39D586C4Q45310365-98006F54-7D30-45DE-A5E1-ED2117015D22Q52608119-3D389EBB-FBFB-408C-8871-D6547F110251Q56592869-27D85123-EE4D-4127-9357-DD526848F6FAQ56592870-A50C927D-9DCA-4D70-9036-2468C20FD4A2Q63344315-BE51EFEA-CD6D-4D4E-89E8-3E3676535E07
P921
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
(E)-3-(p-toluenesulfonyl)acrylonitrile
@en
type
label
(E)-3-(p-toluenesulfonyl)acrylonitrile
@en
altLabel
(3E)3-(p-toluenesulfonyl)acrylonitrile
@en
(E)-3-(4-methylphenylsulfonyl)-2-propenenenitrile
@en
(E)-3-tosylacrylonitrile
@en
BAY-11-7082
@en
BAY-11-7821
@en
BAY-117082
@en
BAY-117821
@en
beta-(cyanovinyl)-p-tolylsulfone
@en
prefLabel
(E)-3-(p-toluenesulfonyl)acrylonitrile
@en
P592
P661
P662
P683
P1579
P2017
CC1=CC=C(C=C1)S(=O)(=O)/C=C/C#N
P2067
P231
19542-67-7
P232
P233
CC1=CC=C(C=C1)S(=O)(=O)C=CC#N
P234
1S/C10H9NO2S/c1-9-3-5-10(6-4-9)14(12,13)8-2-7-11/h2-6,8H,1H3/b8-2+
P235
DOEWDSDBFRHVAP-KRXBUXKQSA-N
P2566
100.232.898
P274
P3117
DTXSID3041459
P592
CHEMBL403183
P652
4Y5G2A4F6O