Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasome - sprookjes - yvandenbroek - TriplyDB

Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasome

Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasome

http://www.wikidata.org/entity/Q33744674

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Recent insights into the molecular mechanisms of the NLRP3 inflammasome activation Lung inflammation caused by inhaled toxicants: a review ROS-Mediated NLRP3 Inflammasome Activation in Brain, Heart, Kidney, and Testis Ischemia/Reperfusion Injury To Extinguish the Fire from Outside the Cell or to Shutdown the Gas Valve Inside? Novel Trends in Anti-Inflammatory Therapies Biochemical and structural aspects of the ATP-binding domain in inflammasome-forming human NLRP proteins Inflammasomes: mechanism of action, role in disease, and therapeutics Deubiquitinases: Novel Therapeutic Targets in Immune Surveillance?The Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease ATP binding by NLRP7 is required for inflammasome activation in response to bacterial lipopeptides Parthenolide-Induced Cytotoxicity in H9c2 Cardiomyoblasts Involves Oxidative Stress The cytokine release inhibitory drug CRID3 targets ASC oligomerisation in the NLRP3 and AIM2 inflammasomes Inflammasome-mediated IL-1β production in humans with cystic fibrosis High Throughput Screen for Escherichia coli Twin Arginine Translocation (Tat) Inhibitors.Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome Activation and regulation of the inflammasomes K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter The AIM2 inflammasome is critical for innate immunity to Francisella tularensis Caspase-1-mediated pathway promotes generation of thromboinflammatory microparticles.Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity.Chikusetsu saponin IVa ameliorates high fat diet-induced inflammation in adipose tissue of mice through inhibition of NLRP3 inflammasome activation and NF-κB signaling.Chlamydial infection of monocytes stimulates IL-1beta secretion through activation of the NLRP3 inflammasome Caspase-1 and -3 inhibiting drimane sesquiterpenoids from the extremophilic fungus Penicillium solitum.Identification and evaluation of twin-arginine translocase inhibitors Interleukin-1β produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T-cells: Implications for the timing of tolerizing immunotherapy.The lysosome rupture-activated TAK1-JNK pathway regulates NLRP3 inflammasome activation.Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy Targeting the NLRP3 inflammasome in chronic inflammatory diseases: current perspectives.3,4-methylenedioxy-β-nitrostyrene inhibits NLRP3 inflammasome activation by blocking assembly of the inflammasome.Shigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkcδ.Current knowledge and future directions of TLR and NOD signaling in sepsis A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.Inflammasome priming is similar for francisella species that differentially induce inflammasome activation.Critical role for NLRP3 in necrotic death triggered by Mycobacterium tuberculosis.Parthenolide Relieves Pain and Promotes M2 Microglia/Macrophage Polarization in Rat Model of Neuropathy.Transcriptome sequencing of microglial cells stimulated with TLR3 and TLR4 ligands.Non-transcriptional regulation of NLRP3 inflammasome signaling by IL-4.Inflammasome-IL-1β Signaling Mediates Ethanol Inhibition of Hippocampal Neurogenesis BAY 11-7082 is a broad-spectrum inhibitor with anti-inflammatory activity against multiple targets.NLRP3 Inflammasome Mediates Chronic Mild Stress-Induced Depression in Mice via Neuroinflammation.Shikonin Suppresses NLRP3 and AIM2 Inflammasomes by Direct Inhibition of Caspase-1.

P2860

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P2860

Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasome

http://www.wikidata.org/entity/Q33744674

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2010 nî lūn-bûn

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2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունվարին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Anti-inflammatory compounds pa ...... inhibitors of the inflammasome

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Anti-inflammatory compounds pa ...... inhibitors of the inflammasome

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Anti-inflammatory compounds pa ...... inhibitors of the inflammasome

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Anti-inflammatory compounds pa ...... inhibitors of the inflammasome

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JBC.M109.082305

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Journal of Biological Chemistry

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Anti-inflammatory compounds pa ...... inhibitors of the inflammasome

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Andrew A Quong

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Charles P Scott

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Christine Juliana

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Eicke Latz

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Emad S Alnemri

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Je-Wook Yu

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Jianghong Wu

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Leobaldo Solorzano

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Pinaki Datta

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Rong Meng

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P2860

Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome

Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

The Nalp3 inflammasome is essential for the development of silicosis

Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome

Vinyl Sulfones as Antiparasitic Agents and a Structural Basis for Drug Design

Aryl Vinyl Sulfonates and Sulfones as Active Site-Directed and Mechanism-Based Probes for Protein Tyrosine Phosphatases

Gout-associated uric acid crystals activate the NALP3 inflammasome

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9792-9802

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scholarly article

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10.1074/JBC.M109.082305

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13

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285

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2010-01-21T00:00:00Z

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20093358

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(E)-3-(p-toluenesulfonyl)acrylonitrile

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2843228

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