A conserved helical element is essential for internal initiation of translation of hepatitis C virus RNA
about
Hepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathwayRibosomal binding to the internal ribosomal entry site of classical swine fever virus.Crystal structure of the HCV IRES central domain reveals strategy for start-codon positioningRNase III cleavage demonstrates a long range RNA: RNA duplex element flanking the hepatitis C virus internal ribosome entry siteInfluence of correct secondary and tertiary RNA folding on the binding of cellular factors to the HCV IRESA phylogenetically conserved stem-loop structure at the 5' border of the internal ribosome entry site of hepatitis C virus is required for cap-independent viral translation.A recombinant hepatitis C virus RNA-dependent RNA polymerase capable of copying the full-length viral RNA.Alterations to both the primary and predicted secondary structure of stem-loop IIIc of the hepatitis C virus 1b 5' untranslated region (5'UTR) lead to mutants severely defective in translation which cannot be complemented in trans by the wild-type 5Analysis of hepatitis C virus-inoculated chimpanzees reveals unexpected clinical profiles.Specific interaction of eukaryotic translation initiation factor 3 with the 5' nontranslated regions of hepatitis C virus and classical swine fever virus RNAs.Heterogeneous nuclear ribonucleoprotein L interacts with the 3' border of the internal ribosomal entry site of hepatitis C virusHepatitis C virus internal ribosome entry site (IRES) stem loop IIId contains a phylogenetically conserved GGG triplet essential for translation and IRES folding.Comparative analysis of translation efficiencies of hepatitis C virus 5' untranslated regions among intraindividual quasispecies present in chronic infection: opposite behaviors depending on cell typeMutational analysis of the GB virus B internal ribosome entry siteAn enzymatic footprinting analysis of the interaction of 40S ribosomal subunits with the internal ribosomal entry site of hepatitis C virusSpecific Interaction of Hepatitis C Virus Protease/Helicase NS3 with the 3'-Terminal Sequences of Viral Positive- and Negative-Strand RNAPestivirus internal ribosome entry site (IRES) structure and function: elements in the 5' untranslated region important for IRES function.cis-acting RNA elements required for replication of bovine viral diarrhea virus-hepatitis C virus 5' nontranslated region chimeras.Mechanism of ribosome recruitment by hepatitis C IRES RNAThe influence of downstream protein-coding sequence on internal ribosome entry on hepatitis C virus and other flavivirus RNAsActivation and evasion of the antiviral 2'-5' oligoadenylate synthetase/ribonuclease L pathway by hepatitis C virus mRNA.Long-range RNA-RNA interaction between the 5' nontranslated region and the core-coding sequences of hepatitis C virus modulates the IRES-dependent translationHepatitis C Virus RNA Synthesis in a Cell-Free System Isolated from Replicon-Containing Hepatoma CellsFunctional analysis of the interaction between HCV 5'UTR and putative subunits of eukaryotic translation initiation factor eIF3An RNA pseudoknot is an essential structural element of the internal ribosome entry site located within the hepatitis C virus 5' noncoding regionRole of the 5'-Proximal Stem-Loop Structure of the 5' Untranslated Region in Replication and Translation of Hepatitis C Virus RNAViral Internal Ribosome Entry Site Elements: Novel Ribosome-RNA Complexes and Roles in Viral PathogenesisDiscovery of significant variants containing large deletions in the 5'UTR of human hepatitis C virus (HCV)In vitro inhibition of hepatitis C virus gene expression by chemically modified antisense oligodeoxynucleotidesInteraction of polypyrimidine tract-binding protein with the 5' noncoding region of the hepatitis C virus RNA genome and its functional requirement in internal initiation of translationAntisense oligonucleotide inhibition of hepatitis C virus gene expression in transformed hepatocytesInternal entry of ribosomes is directed by the 5' noncoding region of classical swine fever virus and is dependent on the presence of an RNA pseudoknot upstream of the initiation codonThe sequence element of the internal ribosome entry site and a 25-kilodalton cellular protein contribute to efficient internal initiation of translation of hepatitis C virus RNAThe La antigen binds 5' noncoding region of the hepatitis C virus RNA in the context of the initiator AUG codon and stimulates internal ribosome entry site-mediated translationThe internal initiation of translation in bovine viral diarrhea virus RNA depends on the presence of an RNA pseudoknot upstream of the initiation codonHigh-Resolution Functional Profiling of Hepatitis C Virus GenomeAnalysis of natural variants of the hepatitis C virus internal ribosome entry site reveals that primary sequence plays a key role in cap-independent translationStructure and function of HCV IRES domainsSingle-nucleotide polymorphisms can cause different structural folds of mRNA.The HCV IRES pseudoknot positions the initiation codon on the 40S ribosomal subunit.
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P2860
A conserved helical element is essential for internal initiation of translation of hepatitis C virus RNA
description
1994 nî lūn-bûn
@nan
1994 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
A conserved helical element is ...... ation of hepatitis C virus RNA
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A conserved helical element is ...... ation of hepatitis C virus RNA
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A conserved helical element is ...... ation of hepatitis C virus RNA
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type
label
A conserved helical element is ...... ation of hepatitis C virus RNA
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A conserved helical element is ...... ation of hepatitis C virus RNA
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A conserved helical element is ...... ation of hepatitis C virus RNA
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A conserved helical element is ...... ation of hepatitis C virus RNA
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A conserved helical element is ...... ation of hepatitis C virus RNA
@en
A conserved helical element is ...... ation of hepatitis C virus RNA
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A conserved helical element is ...... ation of hepatitis C virus RNA
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1994-11-01T00:00:00Z