Hepatitis C virus JFH-1 strain infection in chimpanzees is associated with low pathogenicity and emergence of an adaptive mutation
about
Signal peptidase complex subunit 1 participates in the assembly of hepatitis C virus through an interaction with E2 and NS2Hepatitis C Virus NS2 Protein Contributes to Virus Particle Assembly via Opposing Epistatic Interactions with the E1-E2 Glycoprotein and NS3-NS4A Enzyme ComplexesStructural and Functional Studies of Nonstructural Protein 2 of the Hepatitis C Virus Reveal Its Key Role as Organizer of Virion AssemblyAntiviral activity of glycyrrhizin against hepatitis C virus in vitroSingle strain isolation method for cell culture-adapted hepatitis C virus by end-point dilution and infection.Novel infectious cDNA clones of hepatitis C virus genotype 3a (strain S52) and 4a (strain ED43): genetic analyses and in vivo pathogenesis studiesNovel nucleotide and amino acid covariation between the 5'UTR and the NS2/NS3 proteins of hepatitis C virus: bioinformatic and functional analyses.HCV infection induces a unique hepatic innate immune response associated with robust production of type III interferonsMeta-analysis of hepatitis C virus vaccine efficacy in chimpanzees indicates an importance for structural proteins.In vivo adaptation of hepatitis C virus in chimpanzees for efficient virus production and evasion of apoptosis.Both innate and adaptive immunity mediate protective immunity against hepatitis C virus infection in chimpanzeesProduction of infectious chimeric hepatitis C virus genotype 2b harboring minimal regions of JFH-1.Amino Acid Polymorphisms in Hepatitis C Virus Core Affect Infectious Virus Production and Major Histocompatibility Complex Class I Molecule Expression.Novel cell culture-adapted genotype 2a hepatitis C virus infectious cloneEvolution of a cell culture-derived genotype 1a hepatitis C virus (H77S.2) during persistent infection with chronic hepatitis in a chimpanzeeDendritic cells in hepatitis C infection: can they (help) win the battle?Immune mechanisms of vaccine induced protection against chronic hepatitis C virus infection in chimpanzees.Amino Acid Mutations in the NS4A Region of Hepatitis C Virus Contribute to Viral Replication and Infectious Virus Production25-Hydroxyvitamin D3 suppresses hepatitis C virus production.Replication and infectivity of a novel genotype 1b hepatitis C virus clone.Novel mutations in a tissue culture-adapted hepatitis C virus strain improve infectious-virus stability and markedly enhance infection kinetics.Hepatitis C virus NS2 coordinates virus particle assembly through physical interactions with the E1-E2 glycoprotein and NS3-NS4A enzyme complexes.Identification of residues involved in NS2 homodimerization and elucidation of their impact on the HCV life cycle.The Chimpanzee Model of Viral Hepatitis: Advances in Understanding the Immune Response and Treatment of Viral Hepatitis.Interferon sensitivity-determining region of hepatitis C virus influences virus production and interferon signaling.Defining Breadth of Hepatitis C Virus Neutralization
P2860
Q24322876-419A1A70-73F3-428F-809E-01430D93A493Q27489514-19AF9BB8-9C79-408D-BD5B-3FFEE944D4FFQ27666400-B3BCD6BC-AD58-4F6D-BB4D-9C29A067F079Q28534716-B8B8B562-130D-4419-92F8-F3104FF70E25Q33646044-623D3621-F287-4EDA-944D-F53AD4A8A262Q33826844-2886738B-C283-4A13-B051-B7725ED55C8CQ34043316-006463F6-2DD1-4EFC-8154-6556C727148EQ34247460-0FE6485F-6C50-410D-A6A8-BBD31C91E5A8Q34788785-179ECD19-3C88-4EE8-BA1D-717C23F41E74Q35132005-204ADFEF-26F0-4F85-8ABE-17534058A548Q35249069-C8120D51-E8BE-4B51-BDE4-0A41619D6E08Q35826594-2F833487-97FF-45CD-8398-688B7B249164Q36056232-7867D441-F8D1-452E-88F9-D23B8CC219B6Q36276664-B2D3CCA1-6E4C-4308-AB0F-D2149C4A90AAQ37713524-045E727A-B60F-43A5-87FC-F1D43926E1CDQ37843841-3A7D6CAF-B59B-4D28-A7EC-7EF3269802FDQ38334024-9D70920C-54F7-4CC2-85E2-F0171E18F7E9Q38727226-4CC1EA06-3488-49AE-9EB6-89E01A4DA34BQ39367358-C1654BC0-F059-466C-9E68-B5CF3A094F92Q39399240-57564A9A-72A0-4E47-A1D2-4081D434E9E2Q39598862-03140A1F-7E62-4326-8D86-F228E9D12DD4Q39621458-33EE8828-78F2-451A-9457-D6497C96C633Q42977696-81A27742-4F19-4398-BAB1-3FA1E28C97DCQ47608448-5D125A9A-9D63-41F0-BE3F-AD9E961F94DEQ49787914-67C322FD-5F80-4C81-8165-15F8B87104A0Q56395915-B2A4B310-64FC-451E-8C1C-4F739DCBDC63
P2860
Hepatitis C virus JFH-1 strain infection in chimpanzees is associated with low pathogenicity and emergence of an adaptive mutation
description
2008 nî lūn-bûn
@nan
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Hepatitis C virus JFH-1 strain ...... rgence of an adaptive mutation
@ast
Hepatitis C virus JFH-1 strain ...... rgence of an adaptive mutation
@en
Hepatitis C virus JFH-1 strain ...... rgence of an adaptive mutation
@nl
type
label
Hepatitis C virus JFH-1 strain ...... rgence of an adaptive mutation
@ast
Hepatitis C virus JFH-1 strain ...... rgence of an adaptive mutation
@en
Hepatitis C virus JFH-1 strain ...... rgence of an adaptive mutation
@nl
prefLabel
Hepatitis C virus JFH-1 strain ...... rgence of an adaptive mutation
@ast
Hepatitis C virus JFH-1 strain ...... rgence of an adaptive mutation
@en
Hepatitis C virus JFH-1 strain ...... rgence of an adaptive mutation
@nl
P2093
P2860
P356
P1433
P1476
Hepatitis C virus JFH-1 strain ...... rgence of an adaptive mutation
@en
P2093
Akihiro Furusaka
Gamal Elmowalid
Heidi Barth
Krzysztof Krawczynski
Ronda K Sapp
Shunji Mishiro
T Jake Liang
Takanobu Kato
Youkyung Choi
P2860
P304
P356
10.1002/HEP.22422
P407
P577
2008-09-01T00:00:00Z