The Hepatitis C Virus NS5A Stimulates NS5B During In Vitro RNA Synthesis in a Template Specific Manner

The Hepatitis C Virus NS5A Stimulates NS5B During In Vitro RNA Synthesis in a Template Specific Manner

Item
http://www.wikidata.org/entity/Q27488841
Hepatitis C virus NS5B and host cyclophilin A share a common binding site on NS5AReconstitution and Functional Analysis of a Full-Length Hepatitis C Virus NS5B Polymerase on a Supported Lipid Bilayer.A cell-based assay for RNA synthesis by the HCV polymerase reveals new insights on mechanism of polymerase inhibitors and modulation by NS5AAll three domains of the hepatitis C virus nonstructural NS5A protein contribute to RNA binding.Distinct functions of NS5A in hepatitis C virus RNA replication uncovered by studies with the NS5A inhibitor BMS-790052The hepatitis C virus core protein can modulate RNA-dependent RNA synthesis by the 2a polymerase.Nonstructural protein 5A (NS5A) and human replication protein A increase the processivity of hepatitis C virus NS5B polymerase activity in vitro.Approaches to hepatitis C treatment and cure using NS5A inhibitorsCyclophilin inhibitors: an emerging class of therapeutics for the treatment of chronic hepatitis C infectionOptimizing triple therapy and IFN/RBV-free regimens for hepatitis C virus infection.Inhibition of HCV translation by disrupting the structure and interactions of the viral CRE and 3' X-tail.NS5A inhibitors for the treatment of hepatitis C infection.NMR reveals the intrinsically disordered domain 2 of NS5A protein as an allosteric regulator of the hepatitis C virus RNA polymerase NS5B.The methyltransferase domain of dengue virus protein NS5 ensures efficient RNA synthesis initiation and elongation by the polymerase domain.Infectious Bursal Disease Virus VP3 Upregulates VP1-Mediated RNA-Dependent RNA ReplicationLong term persistence of NS5A inhibitor-resistant hepatitis C virus in patients who failed daclatasvir and asunaprevir therapy.The Stimulatory Mechanism of Hepatitis C Virus NS5A Protein on the NS5B Catalyzed Replication Reaction In Vitro.
P2860

The Hepatitis C Virus NS5A Stimulates NS5B During In Vitro RNA Synthesis in a Template Specific Manner

Item
http://www.wikidata.org/entity/Q27488841
description
2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
article scientifique (publié 2009/04/20)
@fr
articolo scientifico (pubblicato il 2009/04/20)
@it
artigo científico (publicado na 2009/04/20)
@pt
artículu científicu espublizáu en 2009
@ast
scientific article (publication date: 20 April 2009)
@en
vedecký článok (publikovaný 2009/04/20)
@sk
vetenskaplig artikel (publicerad på 2009/04/20)
@sv
videnskabelig artikel (udgivet 2009/04/20)
@da
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The Hepatitis C Virus NS5A Sti ...... in a Template Specific Manner
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The Hepatitis C Virus NS5A Sti ...... in a Template Specific Manner
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The Hepatitis C Virus NS5A Sti ...... in a Template Specific Manner
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The Hepatitis C Virus NS5A Sti ...... in a Template Specific Manner
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The Hepatitis C Virus NS5A Sti ...... in a Template Specific Manner
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The Hepatitis C Virus NS5A Sti ...... in a Template Specific Manner
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The Hepatitis C Virus NS5A Sti ...... in a Template Specific Manner
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The Hepatitis C Virus NS5A Sti ...... in a Template Specific Manner
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P31
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10.2174/1874091X00903010039
P478
P577
P698
P932