Crystal structure of an alpha 1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis
about
Geometric attributes of retaining glycosyltransferase enzymes favor an orthogonal mechanismCrystal structure of mammalian alpha1,6-fucosyltransferase, FUT8Tetrameric structure of the GlfT2 galactofuranosyltransferase reveals a scaffold for the assembly of mycobacterial ArabinogalactanABO(H) blood group A and B glycosyltransferases recognize substrate via specific conformational changes2-O-Phosphorylation of Xylose and 6-O-Sulfation of Galactose in the Protein Linkage Region of Glycosaminoglycans Influence the Glucuronyltransferase-I Activity Involved in the Linkage Region SynthesisCrystal Structure of the Catalytic Domain of Drosophila β1,4-Galactosyltransferase-7Mechanistic Insights into the Retaining Glucosyl-3-phosphoglycerate Synthase from MycobacteriaNatural-product sugar biosynthesis and enzymatic glycodiversification.Mutations in EXTL3 Cause Neuro-immuno-skeletal Dysplasia Syndrome.Identification of domains and amino acids essential to the collagen galactosyltransferase activity of GLT25D1.Two-step mechanism that determines the donor binding specificity of human UDP-N-acetylhexosaminyltransferase.Structural dissection and high-throughput screening of mannosylglycerate synthase.Characterization of specific donor binding to alpha1,4-N-acetylhexosaminyltransferase EXTL2 using isothermal titration calorimetry.Substrate-induced conformational changes and dynamics of UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferase-2.The structural basis for a coordinated reaction catalyzed by a bifunctional glycosyltransferase in chondroitin biosynthesis.Deletion of exon 8 from the EXT1 gene causes multiple osteochondromas (MO) in a family with three affected members.The Vaccinia Virus H3 Envelope Protein, a Major Target of Neutralizing Antibodies, Exhibits a Glycosyltransferase Fold and Binds UDP-GlucoseThe chondroitin polymerase K4CP and the molecular mechanism of selective bindings of donor substrates to two active sites.Streptococcus pneumoniae serotype 11D has a bispecific glycosyltransferase and expresses two different capsular polysaccharide repeating units.Lectin chaperones help direct the maturation of glycoproteins in the endoplasmic reticulum.X-ray crystal structure of leukocyte type core 2 beta1,6-N-acetylglucosaminyltransferase. Evidence for a convergence of metal ion-independent glycosyltransferase mechanism.Critical elements of oligosaccharide acceptor substrates for the Pasteurella multocida hyaluronan synthase.Intermediate trapping on a mutant retaining alpha-galactosyltransferase identifies an unexpected aspartate residue.Glycoscience@Synchrotron: Synchrotron radiation applied to structural glycoscience.Crystal structures of a multifunctional triterpene/flavonoid glycosyltransferase from Medicago truncatula.Identification of key functional residues in the active site of human {beta}1,4-galactosyltransferase 7: a major enzyme in the glycosaminoglycan synthesis pathway.Catalytic mechanism of alpha-retaining glucosyl transfer by Corynebacterium callunae starch phosphorylase: the role of histidine-334 examined through kinetic characterization of site-directed mutants.Analysis of novel alleles of brother of tout-velu, the drosophila ortholog of human EXTL3 using a newly developed FRT42D ovoD chromosome.Biosynthesis of heparan sulfate in EXT1-deficient cells.In vitro heparan sulfate polymerization: crucial roles of core protein moieties of primer substrates in addition to the EXT1-EXT2 interaction.Heparan sulfate polymerization in Drosophila.Crystal structures of eukaryote glycosyltransferases reveal biologically relevant enzyme homooligomers.Computational insights into active site shaping for substrate specificity and reaction regioselectivity in the EXTL2 retaining glycosyltransferase.
P2860
Q21090730-561CDBED-D097-413F-B8BE-AF96DEE7EBD9Q24337064-8CCB6B56-50E8-4D3E-9130-8ECF0D210174Q24608295-DEB4C87D-9504-4952-A003-AE6BF0B67459Q27649533-5AA87A22-532D-4AD3-97A0-B898600DD5C2Q27650294-F36DBAA9-488A-4453-8A15-447C10DD39EDQ27660264-4292441B-120C-4CED-8F27-106EC69A65F4Q27679320-0C20476E-698A-41EC-9FD0-835FBC43EA31Q30492476-5BFA926E-7C16-4F0C-BEC2-F38B9268A3CCQ30668595-B20D3DEC-BB91-43B2-85D6-41764E4FD51FQ34117547-7F41FDCA-F94F-44B1-9AAD-8A5C85EE9E06Q34411574-A32929D4-D916-461D-B099-0E04BC5D396BQ34425961-730E3DA5-E833-41C1-A150-24BEA394F6E2Q35594092-482D3D43-C69F-40BB-AE3A-B6D885B5EF71Q36178738-53C9B643-C87A-4725-ADC2-D9A38D875E47Q36332805-AA892DC5-9245-412C-A745-3707A96B78B4Q36491488-6FC022CD-EA8A-4142-BBE4-AECCA96AD3B4Q36878858-FB74473D-ED5E-4C72-943F-C4FA0531D514Q36973662-F0E9BDBB-E51D-4325-B276-A965B70D1390Q37048457-386EEC34-F6A0-4C2A-8F13-CA925A39A178Q37627987-D2777016-AA17-4854-B5D9-E318B127F837Q38311637-94D01F12-7310-4FDF-A1D1-FC4F1C515199Q38317599-6DA6DB55-F506-4927-9FF9-AC9EDD80AD73Q38342603-C6619E27-35AC-41C1-AF1F-68C8AF682FE7Q39419684-96E81990-6646-491D-8E5D-FC1DA83625F8Q40382501-6ABB232C-3F41-4663-B50C-876D32E45802Q41714436-D71EBE05-B38D-4E8A-A906-D38A5BC6E357Q41791514-1D25E5D1-7CFD-4E5E-9BAB-5A6E0D279552Q42760056-0C477D0D-55FE-4F09-9C1B-BBA61DF0F0EFQ43106082-1333D3FB-AB19-4A1F-8D29-C10307662BECQ44542416-0CF6D05C-E3A5-4E92-A236-DB18ACDB799AQ47070189-2336DDB3-A19E-4B29-AD10-6753527C5918Q47769760-23BE982C-C0B7-4B3F-B051-22B4E8BB0D15Q50107299-CDAA40A2-3FFE-49FD-9EAB-23C70C1197B9
P2860
Crystal structure of an alpha 1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis
description
2003 nî lūn-bûn
@nan
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Crystal structure of an alpha ...... n heparan sulfate biosynthesis
@ast
Crystal structure of an alpha ...... n heparan sulfate biosynthesis
@en
Crystal structure of an alpha ...... n heparan sulfate biosynthesis
@nl
type
label
Crystal structure of an alpha ...... n heparan sulfate biosynthesis
@ast
Crystal structure of an alpha ...... n heparan sulfate biosynthesis
@en
Crystal structure of an alpha ...... n heparan sulfate biosynthesis
@nl
prefLabel
Crystal structure of an alpha ...... n heparan sulfate biosynthesis
@ast
Crystal structure of an alpha ...... n heparan sulfate biosynthesis
@en
Crystal structure of an alpha ...... n heparan sulfate biosynthesis
@nl
P2093
P2860
P356
P1476
Crystal structure of an alpha ...... n heparan sulfate biosynthesis
@en
P2093
Fumiyasu Taniguchi
Hiroshi Kitagawa
Joe M Krahn
Kazuyuki Sugahara
Lars C Pedersen
Lee G Pedersen
Masahiko Negishi
P2860
P304
P356
10.1074/JBC.M210532200
P407
P577
2003-04-18T00:00:00Z