Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5 - sprookjes - yvandenbroek - TriplyDB

Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5

Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5

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Japanese encephalitis-a pathological and clinical perspective Molecular targets for flavivirus drug discovery The role of viral persistence in flavivirus biology Structure and functionality in flavivirus NS-proteins: perspectives for drug design The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases Structural proteomics of dengue virus Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling Flaviviral Replication Complex: Coordination between RNA Synthesis and 5'-RNA Capping A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production Crystal Structure of the Dengue Virus RNA-Dependent RNA Polymerase Catalytic Domain at 1.85-Angstrom Resolution Identification of Residues Critical for the Interferon Antagonist Function of Langat Virus NS5 Reveals a Role for the RNA-Dependent RNA Polymerase Domain De Novo Initiation of RNA Synthesis by the Arterivirus RNA-Dependent RNA Polymerase Structural insights into the mechanism and evolution of the vaccinia virus mRNA cap N7 methyl-transferase Crystal Structure of the NS3 Protease-Helicase from Dengue Virus Genetic Interactions among the West Nile Virus Methyltransferase, the RNA-Dependent RNA Polymerase, and the 5' Stem-Loop of Genomic RNA A Locking Mechanism Regulates RNA Synthesis and Host Protein Interaction by the Hepatitis C Virus Polymerase Specific genetic markers for detecting subtypes of dengue virus serotype-2 in isolates from the states of Oaxaca and Veracruz, Mexico Analysis of a structural homology model of the 2'-O-ribose methyltransferase domain within the vesicular stomatitis virus L protein.Conservation and Variability of West Nile Virus Proteins Recombination in West Nile Virus: minimal contribution to genomic diversity The flavivirus NS5 protein is a true RNA guanylyltransferase that catalyzes a two-step reaction to form the RNA cap structure Focus on flaviviruses: current and future drug targets The NS5 Protein of the Virulent West Nile Virus NY99 Strain Is a Potent Antagonist of Type I Interferon-Mediated JAK-STAT Signaling Structural explanation for the role of Mn2+ in the activity of 6 RNA-dependent RNA polymerase Further Insights into the Roles of GTP and the C Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis Crystal Structure of the Dengue Virus Methyltransferase Bound to a 5′-Capped Octameric RNA Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China A Comprehensive Structure-Function Comparison of Hepatitis C Virus Strain JFH1 and J6 Polymerases Reveals a Key Residue Stimulating Replication in Cell Culture across Genotypes Crystal Structure and Functional Analysis of the SARS-Coronavirus RNA Cap 2′-O-Methyltransferase nsp10/nsp16 Complex Conformational Flexibility of the Dengue Virus RNA-Dependent RNA Polymerase Revealed by a Complex with an Inhibitor Structure of Hepatitis C Virus Polymerase in Complex with Primer-Template RNA Exploiting structure similarity in refinement: automated NCS and target-structure restraints in BUSTER Crystal Structure of the full-length Japanese encephalitis virus NS5 reveals a conserved methyltransferase-polymerase interface A Crystal Structure of the Dengue Virus Non-structural Protein 5 (NS5) Polymerase Delineates Interdomain Amino Acid Residues That Enhance Its Thermostability and de Novo Initiation Activities RNA-dependent RNA polymerase of Japanese encephalitis virus binds the initiator nucleotide GTP to form a mechanistically important pre-initiation state Purification of Zika virus RNA-dependent RNA polymerase and its use to identify small-molecule Zika inhibitors A thiopurine drug inhibits West Nile virus production in cell culture, but not in mice The interface between methyltransferase and polymerase of NS5 is essential for flavivirus replication Sequence-Specific Fidelity Alterations Associated with West Nile Virus Attenuation in Mosquitoes

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Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5

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2007 nî lūn-bûn

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2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2007 թվականի ապրիլին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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Crystal structure of the RNA p ...... virus non-structural protein 5

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Crystal structure of the RNA p ...... virus non-structural protein 5

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Crystal structure of the RNA p ...... virus non-structural protein 5

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Crystal structure of the RNA p ...... virus non-structural protein 5

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Crystal structure of the RNA p ...... virus non-structural protein 5

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Crystal structure of the RNA p ...... virus non-structural protein 5

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Crystal structure of the RNA p ...... virus non-structural protein 5

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Crystal structure of the RNA p ...... virus non-structural protein 5

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Crystal structure of the RNA p ...... virus non-structural protein 5

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Arnaud Gruez

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Marie-Pierre Egloff

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Michael Roberts

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10.1074/JBC.M607273200

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282

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Barbara Selisko

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Jason M. Mackenzie

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2007-04-06T00:00:00Z

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West Nile virus

protein structure

crystal structure