Structure of Antibody F425-B4e8 in Complex with a V3 Peptide Reveals a New Binding Mode for HIV-1 Neutralization - sprookjes - yvandenbroek - TriplyDB

Structure of Antibody F425-B4e8 in Complex with a V3 Peptide Reveals a New Binding Mode for HIV-1 Neutralization

Structure of Antibody F425-B4e8 in Complex with a V3 Peptide Reveals a New Binding Mode for HIV-1 Neutralization

http://www.wikidata.org/entity/Q27649247

about

Current Advances in Virus-Like Particles as a Vaccination Approach against HIV Infection Molecular Basis of Recognition of Human Osteopontin by 23C3, a Potential Therapeutic Antibody for Treatment of Rheumatoid Arthritis A Conformational Switch in Human Immunodeficiency Virus gp41 Revealed by the Structures of Overlapping Epitopes Recognized by Neutralizing Antibodies Structural Basis of the Cross-Reactivity of Genetically Related Human Anti-HIV-1 mAbs: Implications for Design of V3-Based Immunogens Conserved structural elements in the V3 crown of HIV-1 gp120 Crystal Structure of the HIV-2 Neutralizing Fab Fragment 7C8 with High Specificity to the V3 Region of gp125 Structural Analysis of Human and Macaque mAbs 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120 Rabbit Anti-HIV-1 Monoclonal Antibodies Raised by Immunization Can Mimic the Antigen-Binding Modes of Antibodies Derived from HIV-1-Infected Humans Two HIV-1 variants resistant to small molecule CCR5 inhibitors differ in how they use CCR5 for entry Human antibodies that neutralize HIV-1: identification, structures, and B cell ontogenies Anti-V3 monoclonal antibodies display broad neutralizing activities against multiple HIV-1 subtypes Max Bergmann lecture protein epitope mimetics in the age of structural vaccinology Use of silver nanoparticles increased inhibition of cell-associated HIV-1 infection by neutralizing antibodies developed against HIV-1 envelope proteins HIV-1 and influenza antibodies: seeing antigens in new ways An optimally constrained V3 peptide is a better immunogen than its linear homolog or HIV-1 gp120 The presence of glutamine at position 315 but not epitope masking predominantly hinders HIV subtype C neutralization by the anti-V3 antibody B4e8.Differential glycosylation of envelope gp120 is associated with differential recognition of HIV-1 by virus-specific antibodies and cell infection.Structural conservation predominates over sequence variability in the crown of HIV type 1's V3 loop.Structure-guided design and immunological characterization of immunogens presenting the HIV-1 gp120 V3 loop on a CTB scaffold.HIV p24 as scaffold for presenting conformational HIV Env antigens.Hepatitis C virus, human immunodeficiency virus and Pseudomonas phage PS5 triad share epitopes of immunogenic determinants A single amino acid substitution in the C4 region in gp120 confers enhanced neutralization of HIV-1 by modulating CD4 binding sites and V3 loop.Structural basis of clade-specific HIV-1 neutralization by humanized anti-V3 monoclonal antibody KD-247.Computational prediction of neutralization epitopes targeted by human anti-V3 HIV monoclonal antibodies Interaction of the HIV-1 gp120 viral protein V3 loop with bacterial lipopolysaccharide: a pattern recognition inhibition.Structure-function relationships of HIV-1 envelope sequence-variable regions refocus vaccine design A High Throughput Protein Microarray Approach to Classify HIV Monoclonal Antibodies and Variant Antigens.Identification of CD4-Binding Site Dependent Plasma Neutralizing Antibodies in an HIV-1 Infected Indian Individual.What Do Chaotrope-Based Avidity Assays for Antibodies to HIV-1 Envelope Glycoproteins Measure?Functional and Structural Characterization of Human V3-Specific Monoclonal Antibody 2424 with Neutralizing Activity against HIV-1 JRFL Production and characterization of human anti-V3 monoclonal antibodies from the cells of HIV-1 infected Indian donors.Neutralizing antibodies to HIV-1 induced by immunization.Improved induction of antibodies against key neutralizing epitopes by human immunodeficiency virus type 1 gp120 DNA prime-protein boost vaccination compared to gp120 protein-only vaccination Antibodies to the CD4-binding site of HIV-1 gp120 suppress gp120-specific CD4 T cell response while enhancing antibody response.Human immunodeficiency virus type 2 (HIV-2)/HIV-1 envelope chimeras detect high titers of broadly reactive HIV-1 V3-specific antibodies in human plasma.Characterization of humoral responses to soluble trimeric HIV gp140 from a clade A Ugandan field isolate An engineered mutant of HIV-1 gp120 formulated with adjuvant Quil A promotes elicitation of antibody responses overlapping the CD4-binding site The human immunodeficiency virus type 1 envelope spike of primary viruses can suppress antibody access to variable regions Origin and biology of simian immunodeficiency virus in wild-living western gorillas Human immunodeficiency virus-1 gp120 V3 loop for anti-acquired immune deficiency syndrome drug discovery: computer-aided approaches to the problem solving.

P2860

Q26775082-F81DAC21-3C83-4B04-8C91-5D8AAEC9FC74 Q27651515-0381BCF6-4B1F-4D3B-9F3E-94CC3B6E9F68 Q27655865-000238C4-8D2B-4BE9-AC37-C32426D69F75 Q27658173-14E21338-6F83-49C8-82BB-F184A331A0F6 Q27663325-5F9B2F83-A7B4-4D43-8295-2850CC82AFB7 Q27667679-48BBC149-38AF-483F-8FAF-7E1F9123CBAB Q27667819-862B2706-793A-4A82-8467-B67278A4595D Q27679123-4115BB5A-76AF-444C-A517-EC96B57B87E6 Q28475912-6D962D92-CF20-402F-856E-83969BD0F5EB Q28602877-AD98DBB5-B2BF-4E99-979B-470D562750A5 Q28752503-F3711EEE-DB8D-472C-B4B0-96F4E6E12C28 Q30155145-D237880B-1C59-47A4-8BC6-BF31215CCD60 Q30407161-176D1E82-B048-45E1-B60B-7322A69F2D7D Q33552488-8D6383F5-0841-41DC-B733-4035152CC334 Q33820645-C7F98438-E0F3-4E2A-A85B-734D85CC81B9 Q34017550-49514D1C-CA95-4391-BAEF-C08668A916A2 Q34034659-E2E07642-94D3-4C20-A505-310AC9DDAEC9 Q34100194-9A24F58E-42EE-4192-B70C-609FD8F6AD44 Q34128200-971E70FC-B7A7-42BC-9ECA-B8A4771857D8 Q34389522-6159E30B-561F-4793-BE19-104189BF6E3D Q34426709-1AC4B211-7B22-4DE9-90F3-5784701BD7AE Q34463861-D410D504-6929-430E-A10C-61EA13885D88 Q34847834-C4ED3DFC-8E8A-4D8C-A404-B570FC64E692 Q35108505-1819A99C-2BB4-4998-A4CB-D434BA001FD1 Q35111062-BC2DF3D9-7D3D-45C6-9160-6F8B2FA9E3FF Q35196671-7C15129F-8D03-4A63-B52A-87BAF93F9A4B Q35566508-00ADAC12-8340-4602-84EF-9D3C47901588 Q35592911-7D6C30C9-F0ED-451E-8EDF-61430C49E919 Q35641144-84161EDC-BC9A-4B06-86AF-4298B23571FB Q35913910-A03A0114-322B-42B3-A821-74ACD8651C40 Q36384117-84FD9F89-1DCA-4891-A47A-F74D40BC7368 Q36603515-EB025C91-3E69-4E79-BF1A-2B19F0613EF7 Q36804634-6C65EFD4-0B9A-4C4F-8761-E6DC61841E67 Q36823297-C7269651-A552-484B-9FCD-352CAA70293D Q37051645-E4C7841C-41A1-4AFE-87D0-E9B4A52738C0 Q37060319-5DD10BA7-25D1-43B0-821B-D6D35D6318BA Q37069430-74C04689-F32E-4C9A-BBDF-471EA0002CAA Q37099851-D2D7695C-EDBB-40F9-B787-329A4491EDC3 Q37099857-4D5B117B-A349-4EF5-8843-373F244AB478 Q38014473-9076DE10-A11F-4757-B991-2725EDEDD3E8

P2860

Structure of Antibody F425-B4e8 in Complex with a V3 Peptide Reveals a New Binding Mode for HIV-1 Neutralization

http://www.wikidata.org/entity/Q27649247

description

2008 nî lūn-bûn

@nan

2008 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

Structure of Antibody F425-B4e ...... Mode for HIV-1 Neutralization

@ast

Structure of Antibody F425-B4e ...... Mode for HIV-1 Neutralization

@en

Structure of Antibody F425-B4e ...... Mode for HIV-1 Neutralization

@nl

type

label

Structure of Antibody F425-B4e ...... Mode for HIV-1 Neutralization

@ast

Structure of Antibody F425-B4e ...... Mode for HIV-1 Neutralization

@en

Structure of Antibody F425-B4e ...... Mode for HIV-1 Neutralization

@nl

prefLabel

Structure of Antibody F425-B4e ...... Mode for HIV-1 Neutralization

@ast

Structure of Antibody F425-B4e ...... Mode for HIV-1 Neutralization

@en

Structure of Antibody F425-B4e ...... Mode for HIV-1 Neutralization

@nl

P1433

Q27649247-84FFDBB4-D996-4D68-B615-A3BC431C0CD9

P1476

Q27649247-C8A7E0C1-BFD0-4979-9317-1777586CE34B

P2093

Q27649247-07ACCADA-788D-4854-94FB-F4879A40A726

Q27649247-3886A847-0BCE-43D3-AD8E-9FC7B3D31848

Q27649247-4EDD3F6D-E893-45BB-9110-B351A471577C

Q27649247-EAD29F0E-DE17-479B-8853-3348AAA7D994

Q27649247-F620BE77-E4F6-4AD3-AC0D-F8BDF15E0552

Q27649247-F6F3EE39-C436-460A-8F63-8E4F6A48A559

P2860

Q27649247-0E5C761A-237A-4CFF-971E-16A1E24F1A52

Q27649247-13C0A6D2-D489-4E71-ADC7-CC354197221E

Q27649247-15B08F01-2D75-4004-8605-0E8482D1A1DB

Q27649247-1CACC07F-287E-4D22-91B3-5AA2A9376E77

Q27649247-1DAC6CA6-C9E3-4EE0-90CD-D2C44A995DF9

Q27649247-1F7E0CD6-E5AF-47F1-AD88-3DD8C6D44E19

Q27649247-248658F1-3780-48FD-B272-1897FB4511DD

Q27649247-2860A509-DB4A-4971-BDEE-AA87AB056023

Q27649247-2975BB6F-AACF-422D-9BE1-22FCD2C6E739

Q27649247-30FFB6AA-F1D2-4C75-ACA0-5A7CAF442CB2

P304

Q27649247-9D308C8D-98F8-45A9-835A-111EBF6B9590

P31

Q27649247-FCFE8A1B-117F-4D0E-9184-FD9F1CF30C53

P356

Q27649247-A6517FFF-261A-4587-A16B-F4CE593346EF

P407

Q27649247-39BBF0BE-F67B-496C-85C0-B64D8B810DF5

P433

Q27649247-5C327BAD-9E4C-48BA-8A32-7A86D65B6B79

P478

Q27649247-A922EA94-3F03-4AA0-A129-6E8A37D68D47

P50

Q27649247-90F7DDC3-B6B9-48F6-9743-C8077E28A74A

P577

Q27649247-2143EE7A-6869-403C-A4B4-FE82C111206E

P5875

Q27649247-09D65014-0C8C-4608-8ADE-B11669F5ACA8

P698

Q27649247-76C58A55-6AE4-4199-BDAB-CEB4F27DFE55

P921

Q27649247-B3406571-D5F5-418C-8034-BBC65FE33E22

P932

Q27649247-90D13E79-081C-44C0-9F8A-B504BE4C74B9

P356

J.JMB.2007.11.013

P1433

Journal of Molecular Biology

P1476

Structure of Antibody F425-B4e ...... Mode for HIV-1 Neutralization

@en

P2093

Christian H Bell

http://www.w3.org/2001/XMLSchema#string

Dennis R Burton

http://www.w3.org/2001/XMLSchema#string

Ian A Wilson

http://www.w3.org/2001/XMLSchema#string

Lisa A Cavacini

http://www.w3.org/2001/XMLSchema#string

Ralph Pantophlet

http://www.w3.org/2001/XMLSchema#string

Robyn L Stanfield

http://www.w3.org/2001/XMLSchema#string

P2860

The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens

Electrostatics of nanosystems: application to microtubules and the ribosome

Comprehensive cross-clade neutralization analysis of a panel of anti-human immunodeficiency virus type 1 monoclonal antibodies

Structural definition of a conserved neutralization epitope on HIV-1 gp120

Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs

NMR structure of an anti-gp120 antibody complex with a V3 peptide reveals a surface important for co-receptor binding

Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates

Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design

Antibody domain exchange is an immunological solution to carbohydrate cluster recognition

Recurring conformation of the human immunodeficiency virus type 1 gp120 V3 loop

P304

969-78

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.JMB.2007.11.013

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

375

http://www.w3.org/2001/XMLSchema#string

P50

André Schiefner

P577

2008-01-25T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

5779073

http://www.w3.org/2001/XMLSchema#string

P698

18068724

http://www.w3.org/2001/XMLSchema#string

P921

P932

2289799

http://www.w3.org/2001/XMLSchema#string