Structural conservation predominates over sequence variability in the crown of HIV type 1's V3 loop. - sprookjes - yvandenbroek - TriplyDB

Structural conservation predominates over sequence variability in the crown of HIV type 1's V3 loop.

Structural conservation predominates over sequence variability in the crown of HIV type 1's V3 loop.

http://www.wikidata.org/entity/Q34100194

about

Anti-V3 monoclonal antibodies display broad neutralizing activities against multiple HIV-1 subtypes Resistance of Subtype C HIV-1 Strains to Anti-V3 Loop Antibodies.Controlling the HIV/AIDS epidemic: current status and global challenges Visualization of retroviral envelope spikes in complex with the V3 loop antibody 447-52D on intact viruses by cryo-electron tomography.The variable loop 3 in the envelope glycoprotein is critical for the atypical coreceptor usage of an HIV-1 strain.Cross-clade HIV-1 neutralizing antibodies induced with V3-scaffold protein immunogens following priming with gp120 DNA.Cryptic determinant of α4β7 binding in the V2 loop of HIV-1 gp120.Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants.Multimeric scaffolds displaying the HIV-1 envelope MPER induce MPER-specific antibodies and cross-neutralizing antibodies when co-immunized with gp160 DNA Vaccine-induced Human Antibodies Specific for the Third Variable Region of HIV-1 gp120 Impose Immune Pressure on Infecting Viruses Computational prediction of neutralization epitopes targeted by human anti-V3 HIV monoclonal antibodies Functional characterization of two scFv-Fc antibodies from an HIV controller selected on soluble HIV-1 Env complexes: a neutralizing V3- and a trimer-specific gp41 antibody.Structure-function relationships of HIV-1 envelope sequence-variable regions refocus vaccine design Xenoepitope substitution avoids deceptive imprinting and broadens the immune response to foot-and-mouth disease virus.Reactivity to the p305 Epitope of the α1G T-Type Calcium Channel and Autoimmune-Associated Congenital Heart Block Peptide Targeted by Human Antibodies Associated with HIV Vaccine-Associated Protection Assumes a Dynamic α-Helical Structure.Production and characterization of human anti-V3 monoclonal antibodies from the cells of HIV-1 infected Indian donors.Improved outlook on HIV-1 prevention and vaccine development.Human immunodeficiency virus-1 gp120 V3 loop for anti-acquired immune deficiency syndrome drug discovery: computer-aided approaches to the problem solving.Position 22 of the V3 loop is associated with HIV infectivity.Assessment of immunologically relevant dynamic tertiary structural features of the HIV-1 V3 loop crown R2 sequence by ab initio folding Relative reactivity of HIV-1 polyclonal plasma antibodies directed to V3 and MPER regions suggests immunodominance of V3 over MPER and dependence of high anti-V3 antibody titers on virus persistence.Discovery of novel anti-HIV-1 agents based on a broadly neutralizing antibody against the envelope gp120 V3 loop: a computational study.Structural analysis of the envelope gp120 V3 loop for some HIV-1 variants circulating in the countries of Eastern Europe.Mapping mutational effects along the evolutionary landscape of HIV envelope.

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Structural conservation predominates over sequence variability in the crown of HIV type 1's V3 loop.

http://www.wikidata.org/entity/Q34100194

description

2010 nî lūn-bûn

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2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Structural conservation predom ...... crown of HIV type 1's V3 loop.

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Structural conservation predom ...... crown of HIV type 1's V3 loop.

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Structural conservation predom ...... crown of HIV type 1's V3 loop.

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Structural conservation predom ...... crown of HIV type 1's V3 loop.

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Structural conservation predom ...... crown of HIV type 1's V3 loop.

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Structural conservation predom ...... crown of HIV type 1's V3 loop.

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Structural conservation predom ...... crown of HIV type 1's V3 loop.

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Structural conservation predom ...... crown of HIV type 1's V3 loop.

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Structural conservation predom ...... crown of HIV type 1's V3 loop.

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AIDS Research and Human Retroviruses

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Structural conservation predom ...... crown of HIV type 1's V3 loop.

@en

P2093

David Almond

http://www.w3.org/2001/XMLSchema#string

James Swetnam

http://www.w3.org/2001/XMLSchema#string

Susan Zolla-Pazner

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Tetsuya Kimura

http://www.w3.org/2001/XMLSchema#string

Timothy Cardozo

http://www.w3.org/2001/XMLSchema#string

XiangPeng Kong

http://www.w3.org/2001/XMLSchema#string

P2860

Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity

Structural rationale for the broad neutralization of HIV-1 by human monoclonal antibody 447-52D

Structure of Antibody F425-B4e8 in Complex with a V3 Peptide Reveals a New Binding Mode for HIV-1 Neutralization

Structure determination of an anti-HIV-1 Fab 447-52D–peptide complex from an epitaxially twinned data set

Structural Basis of the Cross-Reactivity of Genetically Related Human Anti-HIV-1 mAbs: Implications for Design of V3-Based Immunogens

A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity

A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5

Highly potent and selective inhibition of human immunodeficiency virus by the bicyclam derivative JM3100

Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotype

Structure of a V3-containing HIV-1 gp120 core

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717-723

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scholarly article

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10.1089/AID.2009.0254

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6

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26

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2010-06-01T00:00:00Z

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20560796

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2932551

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