Structural Analysis Reveals Conformational Plasticity in the Recognition of RNA 3′ Ends by the Human La Protein
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A stimulatory role for the La-related protein 4B in translationLARP6 Meets Collagen mRNA: Specific Regulation of Type I Collagen ExpressionLa-Related Protein 4 Binds Poly(A), Interacts with the Poly(A)-Binding Protein MLLE Domain via a Variant PAM2w Motif, and Can Promote mRNA StabilityStructural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65The La-related protein 1-specific domain repurposes HEAT-like repeats to directly bind a 5'TOP sequenceConserved and divergent features of the structure and function of La and La-related proteins (LARPs)ModBase, a database of annotated comparative protein structure models and associated resources.iTRAQ proteomic identification of pVHL-dependent and -independent targets of Egln1 prolyl hydroxylase knockdown in renal carcinoma cells.Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactionsAn intrinsically disordered C terminus allows the La protein to assist the biogenesis of diverse noncoding RNA precursorsThe RNA-binding protein LARP4 regulates cancer cell migration and invasionSynergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module.Structural insight into the mechanism of stabilization of the 7SK small nuclear RNA by LARP7.Analysis of the interaction with the hepatitis C virus mRNA reveals an alternative mode of RNA recognition by the human La proteinLa-motif-dependent mRNA association with Slf1 promotes copper detoxification in yeast.(1)H, (15)N and (13)C chemical shift assignments of the La motif and RRM1 from human LARP6.The association of a La module with the PABP-interacting motif PAM2 is a recurrent evolutionary process that led to the neofunctionalization of La-related proteins.Sjogren syndrome antigen B (SSB)/La promotes global microRNA expression by binding microRNA precursors through stem-loop recognition.Precursor-product discrimination by La protein during tRNA metabolism.Conservation of RNA chaperone activity of the human La-related proteins 4, 6 and 7Bacterial virulence factor inhibits caspase-4/11 activation in intestinal epithelial cells.Targeted deletion of the gene encoding the La autoantigen (Sjögren's syndrome antigen B) in B cells or the frontal brain causes extensive tissue loss.xRRM: a new class of RRM found in the telomerase La family protein p65.The role of LARP1 in translation and beyond.A systematic analysis of the predicted human La protein targets identified a hepatitis B virus infection signature.Phosphorylation of human La protein at Ser 366 by casein kinase II contributes to hepatitis B virus replication and expression in vitro.Unraveling the conformational determinants of LARP7 and 7SK small nuclear RNA by theoretical approaches.LARP4B is an AU-rich sequence associated factor that promotes mRNA accumulation and translation.RNA chaperone activity of human La protein is mediated by variant RNA recognition motifLARP4 mRNA codon-tRNA match contributes to LARP4 activity for ribosomal protein mRNA poly(A) tail length protectionA novel inhibitor of human La protein with anti-HBV activity discovered by structure-based virtual screening and in vitro evaluation.A comprehensive analysis of the La-motif protein superfamily.The RNA chaperone La promotes pre-tRNA maturation via indiscriminate binding of both native and misfolded targets.The La and related RNA-binding proteins (LARPs): structures, functions, and evolving perspectives.Human La binds mRNAs through contacts to the poly(A) tail.
P2860
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P2860
Structural Analysis Reveals Conformational Plasticity in the Recognition of RNA 3′ Ends by the Human La Protein
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2008 nî lūn-bûn
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2008 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2008年の論文
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2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structural Analysis Reveals Co ...... ′ Ends by the Human La Protein
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Structural Analysis Reveals Co ...... ′ Ends by the Human La Protein
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Structural Analysis Reveals Co ...... ′ Ends by the Human La Protein
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Structural Analysis Reveals Co ...... ′ Ends by the Human La Protein
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Structural Analysis Reveals Co ...... ′ Ends by the Human La Protein
@en
Structural Analysis Reveals Co ...... ′ Ends by the Human La Protein
@nl
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Structural Analysis Reveals Co ...... ′ Ends by the Human La Protein
@ast
Structural Analysis Reveals Co ...... ′ Ends by the Human La Protein
@en
Structural Analysis Reveals Co ...... ′ Ends by the Human La Protein
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P2860
P50
P3181
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Structural Analysis Reveals Co ...... ′ Ends by the Human La Protein
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P2093
Elizabeth R Valentine
Olga Kotik-Kogan
P2860
P304
P3181
P356
10.1016/J.STR.2008.02.021
P577
2008-06-01T00:00:00Z