Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65 - sprookjes - yvandenbroek - TriplyDB

Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65

Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65

http://www.wikidata.org/entity/Q27681196

about

The La-Related Proteins, a Family with Connections to Cancer Progress in structural studies of telomerase Structure and sequence elements of the CR4/5 domain of medaka telomerase RNA important for telomerase function The crystal structure of the Split End protein SHARP adds a new layer of complexity to proteins containing RNA recognition motifs Cooperative structure of the heterotrimeric pre-mRNA retention and splicing complex hLARP7 C-terminal domain contains an xRRM that binds the 3' hairpin of 7SK RNA Telomerase structure.Reconstitution of a functional 7SK snRNP Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions Synthesis and discovery of 18α-GAMG as anticancer agent in vitro and in vivo via down expression of protein p65.Synergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module.Prevalent and distinct spliceosomal 3'-end processing mechanisms for fungal telomerase RNA.Structural insight into the mechanism of stabilization of the 7SK small nuclear RNA by LARP7.PSF: nuclear busy-body or nuclear facilitator?Biogenesis of telomerase ribonucleoproteins Structure and function of echinoderm telomerase RNA.The association of a La module with the PABP-interacting motif PAM2 is a recurrent evolutionary process that led to the neofunctionalization of La-related proteins.Structure and folding of the Tetrahymena telomerase RNA pseudoknot.Coarse grained models reveal essential contributions of topological constraints to the conformational free energy of RNA bulges.xRRM: a new class of RRM found in the telomerase La family protein p65.Integrative structural biology of Tetrahymena telomerase - insights into catalytic mechanism and interaction at telomeres.Oxoisoaporphine as Potent Telomerase Inhibitor.Telomerase Mechanism of Telomere Synthesis.Progress in Human and Tetrahymena Telomerase Structure Determination.RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP.New models of Tetrahymena telomerase RNA from experimentally derived constraints and modeling.A new telomerase RNA element that is critical for telomere elongation.The architecture of Tetrahymena telomerase holoenzyme.The devil is in the domain: understanding protein recognition of multiple RNA targets.Molecular recognition of pre-tRNA by Arabidopsis protein-only Ribonuclease P.The La and related RNA-binding proteins (LARPs): structures, functions, and evolving perspectives.Current Perspectives of Telomerase Structure and Function in Eukaryotes with Emerging Views on Telomerase in Human Parasites.LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast.A putative RNA binding protein from Plasmodium vivax apicoplast.LARP7 family proteins have conserved function in telomerase assembly.Pof8 is a La-related protein and a constitutive component of telomerase in fission yeast.Structure of HIV TAR in complex with a Lab-Evolved RRM provides insight into duplex RNA recognition and synthesis of a constrained peptide that impairs transcription

P2860

Q26778934-A34568F0-9CF3-49E0-82C9-AAF05B8E1F28 Q27024292-B1A389B9-1F10-488B-A24E-8D62082F269A Q27680870-40DAFF21-E86D-4852-95A5-043A9A45225D Q27683484-5446615E-6038-4668-8165-C31FE4AB0ECB Q27695614-9D2F0685-82DF-4D62-B2A4-47296EB27616 Q27728130-D2E75F91-24B6-4676-A2C0-2B489A93D9F0 Q33710697-17A0904F-9CB0-4464-B810-1A42C9C9C1FE Q33878635-3357C6F0-AE6E-4239-B3AD-7A9C75E6EF99 Q34498199-143F2259-B5B6-4189-AECC-086646BCDE14 Q34539198-D44FC500-1FC8-4CDE-8715-D7E246DFF989 Q34883293-147156ED-0198-4193-821E-0B5C1EFEAA94 Q34987937-0DBA238A-B3F4-4D8B-9C7A-00CA2B943B19 Q35237079-BFAD2E2B-D6A3-45B6-B926-C4196254F4F9 Q35772782-05CC4F4B-A370-44F2-BCEA-DA478443E30A Q36246606-4EBC07AA-3031-4629-A655-97C8F4B9D0A6 Q36461908-6AD1E64C-8930-4C95-9294-0A6F94D4ED6A Q36481226-8C718A4E-62FC-4713-B918-F9A78275FF9E Q37577393-D6627CA2-5D4D-40A1-A22E-67F2F342FEC3 Q37697428-B60DCAC0-9361-482C-B87D-BCAB451BC408 Q38074795-9737B51C-18AB-4C3A-B2C1-FE9CF6325FB7 Q38293568-0A738BB9-A4DC-4F5F-86F2-9F4E462CAD5A Q38730739-CEA34EFC-8671-455C-AC35-4E1AFE70A4DF Q39111969-3ACEE550-99F9-441C-8219-EA162EBF41A5 Q39182224-EDD68D86-546B-4DE1-9B74-65A4DC435CC7 Q39183526-ACBC6EC9-302D-4B74-BDAC-11EA67685A12 Q40525171-CF99185A-0784-4CCB-821C-064808C91F1A Q41947741-5A9D4E73-8C54-4AE8-A3F3-0A05F7FA8F88 Q42921430-04E06C32-F9E1-43C0-90CB-BA2C494079F3 Q47390148-2A76FAA8-FCDC-40CC-9856-DEBA9BD21BD7 Q47852259-D052DE79-58B0-4FA7-A092-81A2AA6B01B9 Q47985263-76581763-6B5A-48F3-AD9E-867F63A2AD2F Q48023136-A5EB009B-4097-4B38-8CAF-CC042F996C43 Q49538825-EA51B417-C281-424E-81B8-9E269E31B1EA Q50052279-F657A644-BAD3-4F4F-9988-292D5650B93D Q50068202-D8A8B4A0-9FD9-47FD-B0E1-A89397CB3E0C Q50106845-CAD95EC2-A6A7-43FB-BAB4-F3F4BDA4A37D Q56272235-2D3ED712-349C-46C7-91F4-806A49DEF965

P2860

Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65

http://www.wikidata.org/entity/Q27681196

description

2012 nî lūn-bûn

@nan

2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

name

Structural Basis for Telomeras ...... loenzyme La Family Protein p65

@ast

Structural Basis for Telomeras ...... loenzyme La Family Protein p65

@en

Structural Basis for Telomeras ...... loenzyme La Family Protein p65

@nl

type

label

Structural Basis for Telomeras ...... loenzyme La Family Protein p65

@ast

Structural Basis for Telomeras ...... loenzyme La Family Protein p65

@en

Structural Basis for Telomeras ...... loenzyme La Family Protein p65

@nl

prefLabel

Structural Basis for Telomeras ...... loenzyme La Family Protein p65

@ast

Structural Basis for Telomeras ...... loenzyme La Family Protein p65

@en

Structural Basis for Telomeras ...... loenzyme La Family Protein p65

@nl

P1433

Q27681196-54707B7C-6612-43BC-8DAB-F03E279C3F04

P1476

Q27681196-C1867985-E092-41B8-96DF-8ECA2510A248

P2093

Q27681196-234EEF97-0DCB-4233-9818-5CE1A9A14552

Q27681196-3D5DFB48-83FA-4E53-BE5C-079BA7496501

Q27681196-5B2F2F75-C3F4-4EAB-A3C7-EDAB1D666EE3

Q27681196-9526684C-B1F4-4A40-9AA7-34FF610E1088

Q27681196-C749AC7D-AFF4-47FC-8985-042165403E33

P2860

Q27681196-0530D6F7-46AD-47DF-BF4F-3BC9BA4B659D

Q27681196-08FB7FAB-B0DB-4769-BD74-C163B0F8AE8F

Q27681196-0CADAD1E-C4CB-4611-823B-FDEB7D83C2F2

Q27681196-119778F6-7EAE-45B9-8E99-83EB8A9EC879

Q27681196-17EA6D1F-13F9-4B04-9037-FB18188946AD

Q27681196-1B6E89BC-CAE2-4C00-B395-DA7C7EB555E8

Q27681196-210D95D0-024E-4464-AB67-5179A5462F3E

Q27681196-216C3799-75C8-4678-A3B3-5A8A05ECD0A8

Q27681196-227085DB-EAFF-4C06-8ADA-4B1AF3BE27F4

Q27681196-23F9F5E5-6133-4DE9-9260-CFEE9118815F

P304

Q27681196-BA5647C2-A519-41E7-AE88-7580A110C76F

P31

Q27681196-CC2F0BB2-7B7A-44B4-8A95-7204DB193A49

P356

Q27681196-2CF47296-9A02-4308-884B-BC64A06B3C36

P433

Q27681196-58A534B3-C5C1-4311-BCDB-B4C1D3E2C76F

P478

Q27681196-D9B3708F-DFD1-495C-B747-B635577D3A94

P50

Q27681196-34CD2BDA-2C7F-42ED-A1A1-7079D0C7F850

Q27681196-F14CD4A7-5EAF-4DCC-BD61-9BCC5D8BF619

P577

Q27681196-DE836585-326C-4104-B2C8-E04EBF6970B2

P5875

Q27681196-2B0F5E37-379D-445F-A4D5-5525334B4B3E

P698

Q27681196-8E70C8BA-5F54-4A39-9937-EC7413EA4A7B

P921

Q27681196-A9129646-A73C-4A05-8810-36C011287576

P932

Q27681196-8ABB9E6A-D6E5-4C0B-99A6-1CB7D36D1F00

P356

J.MOLCEL.2012.05.018

P1433

P1476

Structural Basis for Telomeras ...... loenzyme La Family Protein p65

@en

P2093

Anooj Patel

http://www.w3.org/2001/XMLSchema#string

Bon-Kyung Koo

http://www.w3.org/2001/XMLSchema#string

Kathleen Collins

http://www.w3.org/2001/XMLSchema#string

Mahavir Singh

http://www.w3.org/2001/XMLSchema#string

Zhonghua Wang

http://www.w3.org/2001/XMLSchema#string

P2860

TALOS+: a hybrid method for predicting protein backbone torsion angles from NMR chemical shifts

PHENIX: a comprehensive Python-based system for macromolecular structure solution

It all comes together at the ends: telomerase structure, function, and biogenesis

The NMR structure of the 38 kDa U1A protein - PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein

Molecular basis of sequence-specific recognition of pre-ribosomal RNA by nucleolin

Structure of the C-terminal domain of human La protein reveals a novel RNA recognition motif coupled to a helical nuclear retention element

Structure of the La motif: a winged helix domain mediates RNA binding via a conserved aromatic patch

Structural Analysis Reveals Conformational Plasticity in the Recognition of RNA 3′ Ends by the Human La Protein

A novel occluded RNA recognition motif in Prp24 unwinds the U6 RNA internal stem loop

Crystal structure at 1.92 A resolution of the RNA-binding domain of the U1A spliceosomal protein complexed with an RNA hairpin

P304

16-26

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.MOLCEL.2012.05.018

http://www.w3.org/2001/XMLSchema#string

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

47

http://www.w3.org/2001/XMLSchema#string

P50

P577

2012-07-13T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

227170410

http://www.w3.org/2001/XMLSchema#string

P698

22705372

http://www.w3.org/2001/XMLSchema#string

P921

P932

3398246

http://www.w3.org/2001/XMLSchema#string