The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
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Association of global DNA methylation and global DNA hydroxymethylation with metals and other exposures in human blood DNA samplesGatekeepers of chromatin: Small metabolites elicit big changes in gene expressionLinks between metabolism and cancerClinical significance of T cell metabolic reprogramming in cancerFundamentals of cancer metabolismMitochondrial metabolic remodeling in response to genetic and environmental perturbationsEpigenetic regulators and their impact on therapy in acute myeloid leukemiaDysregulated metabolism contributes to oncogenesisSuccinate Dehydrogenase Loss in Familial Paraganglioma: Biochemistry, Genetics, and EpigeneticsNew developments in the pathogenesis and therapeutic targeting of the IDH1 mutation in gliomaEpigenetic regulators as promising therapeutic targets in acute myeloid leukemiaIDH1/2 mutations target a key hallmark of cancer by deregulating cellular metabolism in gliomaMolecular biology of gliomas: present and future challengesGenetically-defined metabolic reprogramming in cancerNovel therapeutic targets of tumor metabolismKDM4/JMJD2 histone demethylases: epigenetic regulators in cancer cellsChromatin signatures of cancerPlant Growth Regulator Daminozide Is a Selective Inhibitor of Human KDM2/7 Histone DemethylasesStructures of Human ALKBH5 Demethylase Reveal a Unique Binding Mode for Specific Single-stranded N 6 -Methyladenosine RNA DemethylationTargeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiationIDH mutations in tumorigenesis and their potential role as novel therapeutic targets.Defects in mitochondrial metabolism and cancerA High-Throughput Mass Spectrometry Assay Coupled with Redox Activity Testing Reduces Artifacts and False Positives in Lysine Demethylase ScreeningAn inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells.IDH2R172 mutations define a unique subgroup of patients with angioimmunoblastic T-cell lymphoma.IDH1 and IDH2 mutations as novel therapeutic targets: current perspectivesMetabolic rewiring in melanomaOncometabolites: Unconventional triggers of oncogenic signalling cascadesUndercover: gene control by metabolites and metabolic enzymesMetabolic control of cancer cell stemness: Lessons from iPS cellsThe mitochondrial side of epigeneticsMetabolic consequences of oncogenic IDH mutationsOncometabolites: tailoring our genes2-Hydoxyglutarate: D/Riving Pathology in gLiomaSWT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferationPlants Possess a Cyclic Mitochondrial Metabolic Pathway similar to the Mammalian Metabolic Repair Mechanism Involving Malate Dehydrogenase and l-2-Hydroxyglutarate DehydrogenaseMetabolite damage and its repair or pre-emptionMolecular Markers in Low-Grade Glioma-Toward Tumor ReclassificationThe role of PHD2 mutations in the pathogenesis of erythrocytosis.Role of mitochondrial dysfunction in cancer progression
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P2860
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
@ast
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
@en
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
@nl
type
label
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
@ast
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
@en
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
@nl
prefLabel
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
@ast
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
@en
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
@en
P2093
Esther C Y Woon
Ian J Clifton
Ivanhoe K H Leung
Kar Kheng Yeoh
Lars Hillringhaus
Robert J Klose
Timothy D W Claridge
P2860
P3181
P356
10.1038/EMBOR.2011.43
P50
P577
2011-05-01T00:00:00Z