WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation
about
Wilms tumor 1 mutations in the pathogenesis of acute myeloid leukemiaPhysiological and pathological implications of 5-hydroxymethylcytosine in diseasesHypoxia, Epithelial-Mesenchymal Transition, and TET-Mediated Epigenetic ChangesMolecular landscape of acute myeloid leukemia in younger adults and its clinical relevanceFunctions of TET Proteins in Hematopoietic TransformationThe Mechanisms of Generation, Recognition, and Erasure of DNA 5-Methylcytosine and Thymine OxidationsThe TET2 interactors and their links to hematological malignanciesDenys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modificationsRole of TET enzymes in DNA methylation, development, and cancerSIRT2 activates G6PD to enhance NADPH production and promote leukaemia cell proliferationHSPB1 Enhances SIRT2-Mediated G6PD Activation and Promotes Glioma Cell ProliferationMAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myelomaEpigenetics in normal and malignant hematopoiesis: An overview and update 2017.The genetics of myelodysplastic syndrome: from clonal haematopoiesis to secondary leukaemiaMolecular therapy for acute myeloid leukaemia.Structure of Naegleria Tet-like dioxygenase (NgTet1) in complexes with a reaction intermediate 5-hydroxymethylcytosine DNA.DNA methylation and hydroxymethylation in hematologic differentiation and transformation.Targeting EZH2 and PRC2 dependence as novel anticancer therapy.Epigenetics, TET proteins, and hypoxia in epithelial-mesenchymal transition and tumorigenesisLow Ten-eleven-translocation 2 (TET2) transcript level is independent of TET2 mutation in patients with myeloid neoplasms.Effects of intracerebral hemorrhage on 5-hydroxymethylcytosine modification in mouse brains.Non-catalytic roles for TET1 protein negatively regulating neuronal differentiation through srGAP3 in neuroblastoma cells.Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia.DNA hydroxymethylation controls cardiomyocyte gene expression in development and hypertrophy.Tet2 and Tet3 cooperate with B-lineage transcription factors to regulate DNA modification and chromatin accessibility.DNA methylation profiles in cancer diagnosis and therapeutics.The Methylcytosine Dioxygenase Ten-Eleven Translocase-2 (tet2) Enables Elevated GnRH Gene Expression and Maintenance of Male Reproductive Function.Genetic and epigenetic heterogeneity in acute myeloid leukemia.H3K27 Methylation: A Focal Point of Epigenetic Deregulation in Cancer.Structure and Function of TET Enzymes.A CpG island methylator phenotype in acute myeloid leukemia independent of IDH mutations and associated with a favorable outcome.Alternative roles for oxidized mCs and TETs.TET2 in Normal and Malignant Hematopoiesis.TET Methylcytosine Oxidases in T Cell and B Cell Development and Function.Epigenetic dysregulation of hematopoietic stem cells and preleukemic state.Synthetic essentiality: Targeting tumor suppressor deficiencies in cancer.Mutant IDH: a targetable driver of leukemic phenotypes linking metabolism, epigenetics and transcriptional regulation.Prognostic role of TET2 deficiency in myelodysplastic syndromes: A meta-analysis.Epigenetic upregulation of ARL4C, due to DNA hypomethylation in the 3'-untranslated region, promotes tumorigenesis of lung squamous cell carcinoma.Pharmacologic Targeting of Chromatin Modulators As Therapeutics of Acute Myeloid Leukemia
P2860
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P2860
WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation
description
2015 nî lūn-bûn
@nan
2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
WT1 recruits TET2 to regulate ...... ss leukemia cell proliferation
@ast
WT1 recruits TET2 to regulate ...... ss leukemia cell proliferation
@en
WT1 recruits TET2 to regulate ...... ss leukemia cell proliferation
@nl
type
label
WT1 recruits TET2 to regulate ...... ss leukemia cell proliferation
@ast
WT1 recruits TET2 to regulate ...... ss leukemia cell proliferation
@en
WT1 recruits TET2 to regulate ...... ss leukemia cell proliferation
@nl
prefLabel
WT1 recruits TET2 to regulate ...... ss leukemia cell proliferation
@ast
WT1 recruits TET2 to regulate ...... ss leukemia cell proliferation
@en
WT1 recruits TET2 to regulate ...... ss leukemia cell proliferation
@nl
P2093
P2860
P921
P3181
P1433
P1476
WT1 recruits TET2 to regulate ...... ss leukemia cell proliferation
@en
P2093
Huaipeng Lin
Kun-Liang Guan
Leilei Chen
Mengtao Xiao
Ruibao Ren
P2860
P304
P3181
P356
10.1016/J.MOLCEL.2014.12.023
P407
P577
2015-02-19T00:00:00Z