Structural and mechanistic insights into bisphenols action provide guidelines for risk assessment and discovery of bisphenol A substitutes - sprookjes - yvandenbroek - TriplyDB

Structural and mechanistic insights into bisphenols action provide guidelines for risk assessment and discovery of bisphenol A substitutes

Structural and mechanistic insights into bisphenols action provide guidelines for risk assessment and discovery of bisphenol A substitutes

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Neurological Effects of Bisphenol A and its Analogues Combining 'dry' co-crystallization and in situ diffraction to facilitate ligand screening by X-ray crystallography Androgen and Progesterone Receptors Are Targets for Bisphenol A (BPA), 4-Methyl-2,4-bis-(P-Hydroxyphenyl)Pent-1-Ene--A Potent Metabolite of BPA, and 4-Tert-Octylphenol: A Computational Insight Predictive features of ligand-specific signaling through the estrogen receptor A high-performance renewable thermosetting resin derived from eugenol.Disruption of Steroid Axis, a New Paradigm for Molar Incisor Hypomineralization (MIH).An alternative conformation of ERβ bound to estradiol reveals H12 in a stable antagonist position Diosgenin relieves goiter via the inhibition of thyrocyte proliferation in a mouse model of Graves' disease.Prenatal exposure to BPA alters the epigenome of the rat mammary gland and increases the propensity to neoplastic development Bisphenol A promotes human prostate stem-progenitor cell self-renewal and increases in vivo carcinogenesis in human prostate epithelium.Versatility or promiscuity: the estrogen receptors, control of ligand selectivity and an update on subtype selective ligands.A Demonstration of the Uncertainty in Predicting the Estrogenic Activity of Individual Chemicals and Mixtures From an In Vitro Estrogen Receptor Transcriptional Activation Assay (T47D-KBluc) to the In Vivo Uterotrophic Assay Using Oral Exposure.Competitive molecular docking approach for predicting estrogen receptor subtype α agonists and antagonists.Structural and functional profiling of environmental ligands for estrogen receptors.Estrogenic potency of benzophenone UV filters in breast cancer cells: proliferative and transcriptional activity substantiated by docking analysis In silico discovery and validation of potent small-molecule inhibitors targeting the activation function 2 site of human oestrogen receptor α Combined effects of nonylphenol and bisphenol a on the human prostate epithelial cell line RWPE-1 The molecular mechanism of bisphenol A (BPA) as an endocrine disruptor by interacting with nuclear receptors: insights from molecular dynamics (MD) simulations.Reporter Cell Lines for the Characterization of the Interactions between Human Nuclear Receptors and Endocrine Disruptors.Reporter cell lines to evaluate the selectivity of chemicals for human and zebrafish estrogen and peroxysome proliferator activated γ receptors Gestational bisphenol A exposure and testis development.NMR WaterLOGSY Reveals Weak Binding of Bisphenol A with Amyloid Fibers of a Conserved 11 Residue Peptide from Androgen Receptor Structure-Based Understanding of Binding Affinity and Mode of Estrogen Receptor α Agonists and Antagonists Selective Human Estrogen Receptor Partial Agonists (ShERPAs) for Tamoxifen-Resistant Breast Cancer Extending an in vitro panel for estrogenicity testing: the added value of bioassays for measuring antiandrogenic activities and effects on steroidogenesis.Enamel defects reflect perinatal exposure to bisphenol A The asymmetric binding of PGC-1α to the ERRα and ERRγ nuclear receptor homodimers involves a similar recognition mechanism Expression of Steroid Receptors in Ameloblasts during Amelogenesis in Rat Incisors.Full antagonism of the estrogen receptor without a prototypical ligand side chain.Coexposure to phytoestrogens and bisphenol a mimics estrogenic effects in an additive manner Fluorene-9-bisphenol is anti-oestrogenic and may cause adverse pregnancy outcomes in mice.Endocrine-disrupting potentials of equine estrogens equilin, equilenin, and their metabolites, in the medaka Oryzias latipes: in silico and DNA microarray studies.Experimental and computational insights on the recognition mechanism between the estrogen receptor α with bisphenol compounds.Bio-Based Aromatic Epoxy Monomers for Thermoset Materials.Ecdysteroids: A novel class of anabolic agents?Bisphenol A regulates the estrogen receptor alpha signaling in developing hippocampus of male rats through estrogen receptor.A structural perspective on nuclear receptors as targets of environmental compounds.Estrogenicity of halogenated bisphenol A: in vitro and in silico investigations.Development and evaluation of microwave-assisted and ultrasound-assisted methods based on a quick, easy, cheap, effective, rugged, and safe sample preparation approach for the determination of bisphenol analogues in serum and sediments.Molecular interactions of bisphenols and analogs with glucocorticoid biosynthetic pathway enzymes: an in silico approach.

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Structural and mechanistic insights into bisphenols action provide guidelines for risk assessment and discovery of bisphenol A substitutes

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2012 nî lūn-bûn

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2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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Structural and mechanistic ins ...... ery of bisphenol A substitutes

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Structural and mechanistic ins ...... ery of bisphenol A substitutes

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Structural and mechanistic ins ...... ery of bisphenol A substitutes

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Structural and mechanistic ins ...... ery of bisphenol A substitutes

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PNAS.1203574109

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Proceedings of the National Academy of Sciences of the United States of America

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Structural and mechanistic ins ...... ery of bisphenol A substitutes

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Abdelhay Boulahtouf

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Jean-Luc Pons

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Marina Grimaldi

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Patrick Balaguer

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Synergy between estrogen receptor alpha activation functions AF1 and AF2 mediated by transcription intermediary factor TIF2.

Synergism between ERalpha transactivation function 1 (AF-1) and AF-2 mediated by steroid receptor coactivator protein-1: requirement for the AF-1 alpha-helical core and for a direct interaction between the N- and C-terminal domains

An extensive new literature concerning low-dose effects of bisphenol A shows the need for a new risk assessment

Bisphenol-A and the great divide: a review of controversies in the field of endocrine disruption

Exposure to environmentally relevant doses of the xenoestrogen bisphenol-A alters development of the fetal mouse mammary gland

Direct evidence revealing structural elements essential for the high binding ability of bisphenol A to human estrogen-related receptor-gamma

Prenatal exposure to bisphenol a at environmentally relevant doses adversely affects the murine female reproductive tract later in life

In vivo effects of bisphenol A in laboratory rodent studies

Structural evidence for endocrine disruptor bisphenol A binding to human nuclear receptor ERR gamma

Modulators of the structural dynamics of the retinoid X receptor to reveal receptor function

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14930-14935

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scholarly article

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2140761

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10.1073/PNAS.1203574109

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37

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109

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William Bourguet

Vanessa Delfosse

Albane le Maire

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2012-08-27T00:00:00Z

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235607799

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22927406

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3443136

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