Full antagonism of the estrogen receptor without a prototypical ligand side chain.
about
Adamantyl Antiestrogens with Novel Side Chains Reveal a Spectrum of Activities in Suppressing Estrogen Receptor Mediated Activities in Breast Cancer Cells.Exploring the Structural Compliancy versus Specificity of the Estrogen Receptor Using Isomeric Three-Dimensional Ligands.Estrogenicity of halogenated bisphenol A: in vitro and in silico investigations.An overview of hydrogen deuterium exchange mass spectrometry (HDX-MS) in drug discovery.A Computational Assay of Estrogen Receptor α Antagonists Reveals the Key Common Structural Traits of Drugs Effectively Fighting Refractory Breast Cancers.Specific stereochemistry of OP-1074 disrupts estrogen receptor alpha helix 12 and confers pure antiestrogenic activity.
P2860
Full antagonism of the estrogen receptor without a prototypical ligand side chain.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
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2016年學術文章
@zh-hant
name
Full antagonism of the estrogen receptor without a prototypical ligand side chain.
@en
Full antagonism of the estrogen receptor without a prototypical ligand side chain.
@nl
type
label
Full antagonism of the estrogen receptor without a prototypical ligand side chain.
@en
Full antagonism of the estrogen receptor without a prototypical ligand side chain.
@nl
prefLabel
Full antagonism of the estrogen receptor without a prototypical ligand side chain.
@en
Full antagonism of the estrogen receptor without a prototypical ligand side chain.
@nl
P2093
P2860
P356
P1476
Full antagonism of the estrogen receptor without a prototypical ligand side chain.
@en
P2093
Benita S Katzenellenbogen
Devrishi Goswami
Hai-Bing Zhou
Jason Nowak
John A Katzenellenbogen
Jonna Frasor
Kendall W Nettles
Nelson E Bruno
Nittaya Boonmuen
P2860
P2888
P304
P356
10.1038/NCHEMBIO.2236
P577
2016-11-21T00:00:00Z
P6179
1005434607