Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth
about
Novel drugs that target the metabolic reprogramming in renal cell cancerMetabolic, autophagic, and mitophagic activities in cancer initiation and progressionMitochondria in Cancer Energy Metabolism: Culprits or Bystanders?Energy metabolism in neurodevelopment and medulloblastoma6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signallingSerine, glycine and one-carbon units: cancer metabolism in full circleDisruptive chemicals, senescence and immortalityTyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformationHeterogeneity of glycolysis in cancers and therapeutic opportunities.A mitochondrial RNAi screen defines cellular bioenergetic determinants and identifies an adenylate kinase as a key regulator of ATP levelsOxidative stress activates SIRT2 to deacetylate and stimulate phosphoglycerate mutaseIdentification of Epigallocatechin-3- Gallate as an Inhibitor of Phosphoglycerate Mutase 1.Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy?Lysine acetylation activates 6-phosphogluconate dehydrogenase to promote tumor growth.A joint analysis of metabolomics and genetics of breast cancer.Techniques to monitor glycolysis.Persistent overexpression of phosphoglycerate mutase, a glycolytic enzyme, modifies energy metabolism and reduces stress resistance of heart in miceGlutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth.An epitope tag alters phosphoglycerate dehydrogenase structure and impairs ability to support cell proliferation.HDAC8, A Potential Therapeutic Target for the Treatment of Malignant Peripheral Nerve Sheath Tumors (MPNST)Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers.Metabolic Rewiring by Oncogenic BRAF V600E Links Ketogenesis Pathway to BRAF-MEK1 SignalingMetabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors.Expression of PGAM1 in renal clear cell carcinoma and its clinical significance.Identification of gene-drug interactions that impact patient survival in TCGA.BAG3 elevation inhibits cell proliferation via direct interaction with G6PD in hepatocellular carcinomas.PARP14 promotes the Warburg effect in hepatocellular carcinoma by inhibiting JNK1-dependent PKM2 phosphorylation and activation.Integrated phosphoproteomic and metabolomic profiling reveals NPM-ALK-mediated phosphorylation of PKM2 and metabolic reprogramming in anaplastic large cell lymphoma.A nuclear-directed human pancreatic ribonuclease (PE5) targets the metabolic phenotype of cancer cells.HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutationsCancer metabolism: fatty acid oxidation in the limelight.Senescence-inducing stress promotes proteolysis of phosphoglycerate mutase via ubiquitin ligase Mdm2.Altered glutamine metabolism and therapeutic opportunities for lung cancer.Dynamic pressurization induces transition of notochordal cells to a mature phenotype while retaining production of important patterning ligands from development.Molecular dynamics simulation reveals how phosphorylation of tyrosine 26 of phosphoglycerate mutase 1 upregulates glycolysis and promotes tumor growth.Post-translational modifications and the Warburg effect.Stress eating and tuning out: cancer cells re-wire metabolism to counter stress.The role of phosphoglycerate mutase 1 in tumor aerobic glycolysis and its potential therapeutic implications.Targeting glucose metabolism in patients with cancer.The pentose phosphate pathway and cancer.
P2860
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P2860
Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth
description
2012 nî lūn-bûn
@nan
2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth
@ast
Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth
@en
Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth
@nl
type
label
Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth
@ast
Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth
@en
Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth
@nl
prefLabel
Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth
@ast
Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth
@en
Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth
@nl
P2093
P2860
P50
P3181
P1433
P1476
Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth
@en
P2093
Benjamin H Lee
Changliang Shan
Chi-Hao Luan
Dong M Shin
Fadlo R Khuri
Gary LeRoy
Georgia Z Chen
Hanna J Khoury
Hee-Bum Kang
P2860
P304
P3181
P356
10.1016/J.CCR.2012.09.020
P577
2012-11-13T00:00:00Z