Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation
about
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signallingHeterogeneity of glycolysis in cancers and therapeutic opportunities.Identification of Epigallocatechin-3- Gallate as an Inhibitor of Phosphoglycerate Mutase 1.Phosphorylation-mediated activation of LDHA promotes cancer cell invasion and tumour metastasisTyr-94 phosphorylation inhibits pyruvate dehydrogenase phosphatase 1 and promotes tumor growth.Lysine acetylation activates 6-phosphogluconate dehydrogenase to promote tumor growth.Tyr-301 phosphorylation inhibits pyruvate dehydrogenase by blocking substrate binding and promotes the Warburg effect.Profiling the tyrosine phosphoproteome of different mouse mammary tumour models reveals distinct, model-specific signalling networks and conserved oncogenic pathways.Effect of Embryo Vitrification on Rabbit Foetal Placenta Proteome during PregnancyMetabolic Rewiring by Oncogenic BRAF V600E Links Ketogenesis Pathway to BRAF-MEK1 SignalingO-GlcNAcylation of G6PD promotes the pentose phosphate pathway and tumor growth.Molecular dynamics simulation reveals how phosphorylation of tyrosine 26 of phosphoglycerate mutase 1 upregulates glycolysis and promotes tumor growth.Post-translational modifications and the Warburg effect.The role of phosphoglycerate mutase 1 in tumor aerobic glycolysis and its potential therapeutic implications.Targeting glucose metabolism in patients with cancer.Dysregulated glycolysis as an oncogenic event.Metabolic control of signalling pathways and metabolic auto-regulation.PGAM1 is Involved in Spermatogenic Dysfunction and Affects Cell Proliferation, Apoptosis, and Migration.Deacetylation of phosphoglycerate mutase in its distinct central region by SIRT2 down-regulates its enzymatic activity.What has passed is prolog: new cellular and physiological roles of G6PD.Phosphoglycerate mutase 1 promotes cancer cell migration independent of its metabolic activity.Phosphoglycerate Mutase 1 Predicts the Poor Prognosis of Oral Squamous Cell Carcinoma and is Associated with Cell Migration.Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells.Conformation and dynamics of the C-terminal region in human phosphoglycerate mutase 1.Bisphosphoglycerate mutase controls serine pathway flux via 3-phosphoglycerate.Phosphoglycerate mutase 1 knockdown inhibits prostate cancer cell growth, migration, and invasion.
P2860
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P2860
Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation
description
2013 nî lūn-bûn
@nan
2013 թուականին հրատարակուած գիտական յօդուած
@hyw
2013 թվականին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Tyr26 phosphorylation of PGAM1 ...... lizing the active conformation
@ast
Tyr26 phosphorylation of PGAM1 ...... lizing the active conformation
@en
Tyr26 phosphorylation of PGAM1 ...... lizing the active conformation
@nl
type
label
Tyr26 phosphorylation of PGAM1 ...... lizing the active conformation
@ast
Tyr26 phosphorylation of PGAM1 ...... lizing the active conformation
@en
Tyr26 phosphorylation of PGAM1 ...... lizing the active conformation
@nl
prefLabel
Tyr26 phosphorylation of PGAM1 ...... lizing the active conformation
@ast
Tyr26 phosphorylation of PGAM1 ...... lizing the active conformation
@en
Tyr26 phosphorylation of PGAM1 ...... lizing the active conformation
@nl
P2093
P2860
P356
P1476
Tyr26 phosphorylation of PGAM1 ...... lizing the active conformation
@en
P2093
Changliang Shan
Dong M Shin
Fadlo R Khuri
Gary LeRoy
Georgia Z Chen
Hanna J Khoury
Hee-Bum Kang
Jae-Ho Seo
Jianxin Xie
P2860
P2888
P356
10.1038/NCOMMS2759
P407
P577
2013-01-01T00:00:00Z
P5875
P6179
1020488951