Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain
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Calcium induced regulation of skeletal troponin--computational insights from molecular dynamics simulationsBepridil opens the regulatory N-terminal lobe of cardiac troponin CStructure of the C-domain of human cardiac troponin C in complex with the Ca2+ sensitizing drug EMD 57033Structure of the regulatory N-domain of human cardiac troponin C in complex with human cardiac troponin I147-163 and bepridilStructure and dynamics of the C-domain of human cardiac troponin C in complex with the inhibitory region of human cardiac troponin ISolution Structure of Human Cardiac Troponin C in Complex with the Green Tea Polyphenol, (-)-Epigallocatechin 3-GallateSolution Structure of the Apo C-Terminal Domain of the Lethocerus F1 Troponin C IsoformStructure of trans -Resveratrol in Complex with the Cardiac Regulatory Protein Troponin CSolution structures of yeast Saccharomyces cerevisiae calmodulin in calcium- and target peptide-bound states reveal similarities and differences to vertebrate calmodulinDrug binding to cardiac troponin CCa(2+)-regulated structural changes in troponinRegulatory domain of troponin moves dynamically during activation of cardiac muscleThe cardiac-specific N-terminal region of troponin I positions the regulatory domain of troponin CTargeting the sarcomere to correct muscle functionDefining the binding site of levosimendan and its analogues in a regulatory cardiac troponin C-troponin I complexCa2+ - and cross-bridge-dependent changes in N- and C-terminal structure of troponin C in rat cardiac muscle.Influence of length on force and activation-dependent changes in troponin c structure in skinned cardiac and fast skeletal muscle.Structure and function of cardiac troponin C (TNNC1): Implications for heart failure, cardiomyopathies, and troponin modulating drugsA model of calcium activation of the cardiac thin filamentBinding of levosimendan, a calcium sensitizer, to cardiac troponin C.Conformations of the regulatory domain of cardiac troponin C examined by residual dipolar couplings.Solution structure and main chain dynamics of the regulatory domain (Residues 1-91) of human cardiac troponin C.Amide hydrogens reveal a temperature-dependent structural transition that enhances site-II Ca2+-binding affinity in a C-domain mutant of cardiac troponin CCa(2+)-regulatory function of the inhibitory peptide region of cardiac troponin I is aided by the C-terminus of cardiac troponin T: Effects of familial hypertrophic cardiomyopathy mutations cTnI R145G and cTnT R278C, alone and in combination, on filPredicting cardiomyopathic phenotypes by altering Ca2+ affinity of cardiac troponin C.Mutations in the N- and D-helices of the N-domain of troponin C affect the C-domain and regulatory functionThe calcium-saturated cTnI/cTnC complex: structure of the inhibitory region of cTnI.Cross-bridge versus thin filament contributions to the level and rate of force development in cardiac muscle.Structure of the inhibitory region of troponin by site directed spin labeling electron paramagnetic resonanceA computational exploration of the interactions of the green tea polyphenol (-)-Epigallocatechin 3-Gallate with cardiac muscle troponin CDifferential effects of bepridil on functional properties of troponin C in slow and fast skeletal musclesThe role of the Ca(2+) regulatory sites of skeletal troponin C in modulating muscle fibre reactivity to the Ca(2+) sensitizer bepridilCooperative cross-bridge activation of thin filaments contributes to the Frank-Starling mechanism in cardiac muscle.Dynamics and calcium association to the N-terminal regulatory domain of human cardiac troponin C: a multiscale computational studyFluorescent Protein-Based Ca2+ Sensor Reveals Global, Divalent Cation-Dependent Conformational Changes in Cardiac Troponin CStructural and functional consequences of the cardiac troponin C L48Q Ca(2+)-sensitizing mutation.An interdomain distance in cardiac troponin C determined by fluorescence spectroscopy.Troponin I Mutations R146G and R21C Alter Cardiac Troponin Function, Contractile Properties, and Modulation by Protein Kinase A (PKA)-mediated Phosphorylation.Long-timescale molecular dynamics simulations elucidate the dynamics and kinetics of exposure of the hydrophobic patch in troponin CUsing lanthanide ions to align troponin complexes in solution: order of lanthanide occupancy in cardiac troponin C.
P2860
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P2860
Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain
description
1997 nî lūn-bûn
@nan
1997 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain
@ast
Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain
@en
Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain
@nl
type
label
Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain
@ast
Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain
@en
Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain
@nl
prefLabel
Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain
@ast
Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain
@en
Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain
@nl
P2093
P2860
P3181
P356
P1476
Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain
@en
P2093
J A Putkey
L Spyracopoulos
P2860
P304
P3181
P356
10.1074/JBC.272.29.18216
P407
P577
1997-07-18T00:00:00Z