Vesicle-mediated protein transport: regulatory interactions between the Vps15 protein kinase and the Vps34 PtdIns 3-kinase essential for protein sorting to the vacuole in yeast
about
Myotubularin, a protein tyrosine phosphatase mutated in myotubular myopathy, dephosphorylates the lipid second messenger, phosphatidylinositol 3-phosphateCharacterization of myotubularin-related protein 7 and its binding partner, myotubularin-related protein 9Characterization of p150, an adaptor protein for the human phosphatidylinositol (PtdIns) 3-kinase. Substrate presentation by phosphatidylinositol transfer protein to the p150.Ptdins 3-kinase complexRegulation of Fab1 phosphatidylinositol 3-phosphate 5-kinase pathway by Vac7 protein and Fig4, a polyphosphoinositide phosphatase family member.Cloning of a human phosphoinositide 3-kinase with a C2 domain that displays reduced sensitivity to the inhibitor wortmanninLocalization of phosphatidylinositol 3-phosphate in yeast and mammalian cellshVps15, but not Ca2+/CaM, is required for the activity and regulation of hVps34 in mammalian cellsDistinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complexAutophagic processes in yeast: mechanism, machinery and regulationMicroRNA-mediated autophagic signaling networks and cancer chemoresistancePhosphoinositides: tiny lipids with giant impact on cell regulationStructure and Function of Vps15 in the Endosomal G Protein Signaling Pathway ,Lipid binding requirements for oxysterol-binding protein Kes1 inhibition of autophagy and endosome-trans-Golgi trafficking pathways.Novel PtdIns(3)P-binding protein Etf1 functions as an effector of the Vps34 PtdIns 3-kinase in autophagy.Sac1 lipid phosphatase and Stt4 phosphatidylinositol 4-kinase regulate a pool of phosphatidylinositol 4-phosphate that functions in the control of the actin cytoskeleton and vacuole morphology.Osmotic stress-induced increase of phosphatidylinositol 3,5-bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p.Fab1p is essential for PtdIns(3)P 5-kinase activity and the maintenance of vacuolar size and membrane homeostasisNovel Golgi to vacuole delivery pathway in yeast: identification of a sorting determinant and required transport component.Formation of AP-3 transport intermediates requires Vps41 function.Atg21 is a phosphoinositide binding protein required for efficient lipidation and localization of Atg8 during uptake of aminopeptidase I by selective autophagy.Two novel WD40 domain-containing proteins, Ere1 and Ere2, function in the retromer-mediated endosomal recycling pathway.Pep7p provides a novel protein that functions in vesicle-mediated transport between the yeast Golgi and endosomeAtg27 is required for autophagy-dependent cycling of Atg9Distinct roles for the yeast phosphatidylinositol 4-kinases, Stt4p and Pik1p, in secretion, cell growth, and organelle membrane dynamics.Structure of the novel C-terminal domain of vacuolar protein sorting 30/autophagy-related protein 6 and its specific role in autophagy.Identification and characterization of an essential family of inositol polyphosphate 5-phosphatases (INP51, INP52 and INP53 gene products) in the yeast Saccharomyces cerevisiae.A yeast protein related to a mammalian Ras-binding protein, Vps9p, is required for localization of vacuolar proteins.Novel syntaxin homologue, Pep12p, required for the sorting of lumenal hydrolases to the lysosome-like vacuole in yeast.A multispecificity syntaxin homologue, Vam3p, essential for autophagic and biosynthetic protein transport to the vacuole.The Saccharomyces cerevisiae LSB6 gene encodes phosphatidylinositol 4-kinase activity.Endosome to Golgi retrieval of the vacuolar protein sorting receptor, Vps10p, requires the function of the VPS29, VPS30, and VPS35 gene products.AUT3, a serine/threonine kinase gene, is essential for autophagocytosis in Saccharomyces cerevisiaeVps34p is required for the decline of extracellular fructose-1,6-bisphosphatase in the vacuole import and degradation pathway.Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiaeRoles of phosphoinositides and of Spo14p (phospholipase D)-generated phosphatidic acid during yeast sporulationAssortment of phosphatidylinositol 3-kinase complexes--Atg14p directs association of complex I to the pre-autophagosomal structure in Saccharomyces cerevisiae.Overexpression of a rat kinase-deficient phosphoinositide 3-kinase, Vps34p, inhibits cathepsin D maturationWortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reactionAn overview of the molecular mechanism of autophagy.A sorting nexin PpAtg24 regulates vacuolar membrane dynamics during pexophagy via binding to phosphatidylinositol-3-phosphate
P2860
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P2860
Vesicle-mediated protein transport: regulatory interactions between the Vps15 protein kinase and the Vps34 PtdIns 3-kinase essential for protein sorting to the vacuole in yeast
description
1995 nî lūn-bûn
@nan
1995 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Vesicle-mediated protein trans ...... orting to the vacuole in yeast
@ast
Vesicle-mediated protein trans ...... orting to the vacuole in yeast
@en
Vesicle-mediated protein trans ...... rting to the vacuole in yeast.
@nl
type
label
Vesicle-mediated protein trans ...... orting to the vacuole in yeast
@ast
Vesicle-mediated protein trans ...... orting to the vacuole in yeast
@en
Vesicle-mediated protein trans ...... rting to the vacuole in yeast.
@nl
prefLabel
Vesicle-mediated protein trans ...... orting to the vacuole in yeast
@ast
Vesicle-mediated protein trans ...... orting to the vacuole in yeast
@en
Vesicle-mediated protein trans ...... rting to the vacuole in yeast.
@nl
P2093
P2860
P356
P1476
Vesicle-mediated protein trans ...... orting to the vacuole in yeast
@en
P2093
P2860
P304
P356
10.1083/JCB.129.2.321
P407
P577
1995-04-01T00:00:00Z