Wnt1-lmx1a forms a novel autoregulatory loop and controls midbrain dopaminergic differentiation synergistically with the SHH-FoxA2 pathway
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Migration of bone marrow progenitor cells in the adult brain of rats and rabbitsInduced pluripotent stem cell technology and direct conversion: new possibilities to study and treat Parkinson's diseaseWnt/β-catenin signaling in midbrain dopaminergic neuron specification and neurogenesis.Functional consequences of 17q21.31/WNT3-WNT9B amplification in hPSCs with respect to neural differentiationDopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's diseaseOtx2 Requires Lmx1b to Control the Development of Mesodiencephalic Dopaminergic NeuronsDoublesex and mab-3-related transcription factor 5 promotes midbrain dopaminergic identity in pluripotent stem cells by enforcing a ventral-medial progenitor fateWnt5a cooperates with canonical Wnts to generate midbrain dopaminergic neurons in vivo and in stem cellsLmx1a encodes a rostral set of mesodiencephalic dopaminergic neurons marked by the Wnt/B-catenin signaling activator R-spondin 2Molecular organization and timing of Wnt1 expression define cohorts of midbrain dopamine neuron progenitors in vivoGenetic dissection of midbrain dopamine neuron development in vivo.En1 and Wnt signaling in midbrain dopaminergic neuronal development.Expansion of human midbrain floor plate progenitors from induced pluripotent stem cells increases dopaminergic neuron differentiation potentialComprehensive gene expression analysis of human embryonic stem cells during differentiation into neural cellsSelection Based on FOXA2 Expression Is Not Sufficient to Enrich for Dopamine Neurons From Human Pluripotent Stem CellsEctopic Wnt/beta-catenin signaling induces neurogenesis in the spinal cord and hindbrain floor plate.Gli1 is an inducing factor in generating floor plate progenitor cells from human embryonic stem cellsMutanlallemand (mtl) and Belly Spot and Deafness (bsd) are two new mutations of Lmx1a causing severe cochlear and vestibular defects.Nurr1 represses tyrosine hydroxylase expression via SIRT1 in human neural stem cellsDNA-dependent protein kinase is a context dependent regulator of Lmx1a and midbrain specification.ES cell-derived renewable and functional midbrain dopaminergic progenitors.An Lmx1b-miR135a2 regulatory circuit modulates Wnt1/Wnt signaling and determines the size of the midbrain dopaminergic progenitor pool.Dopaminergic-like neurons derived from oral mucosa stem cells by developmental cues improve symptoms in the hemi-parkinsonian rat modelMicroRNA-mediated dysregulation of neural developmental genes in HPRT deficiency: clues for Lesch-Nyhan disease?Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson's diseaseSelective Generation of Dopaminergic Precursors from Mouse Fibroblasts by Direct Lineage Conversion.Specification of midbrain dopamine neurons from primate pluripotent stem cells.Dopaminergic neurons modulate GABA neuron migration in the embryonic midbrain.Lmx1a regulates dopamine transporter gene expression during ES cell differentiation and mouse embryonic developmentExcessive Wnt/beta-catenin signaling promotes midbrain floor plate neurogenesis, but results in vacillating dopamine progenitors.Dynamic temporal requirement of Wnt1 in midbrain dopamine neuron development.Expression and functional analysis of the Wnt/beta-catenin induced mir-135a-2 locus in embryonic forebrain development.Temporal and spatial requirements of Smoothened in ventral midbrain neuronal developmentDifferentiation and Characterization of Dopaminergic Neurons From Baboon Induced Pluripotent Stem Cells.Macrophage migration inhibitory factor promotes proliferation and neuronal differentiation of neural stem/precursor cells through Wnt/β-catenin signal pathway.Functional roles of Nurr1, Pitx3, and Lmx1a in neurogenesis and phenotype specification of dopamine neurons during in vitro differentiation of embryonic stem cells.Otx genes in neurogenesis of mesencephalic dopaminergic neurons.Cellular programming and reprogramming: sculpting cell fate for the production of dopamine neurons for cell therapy.Wnt and lithium: a common destiny in the therapy of nervous system pathologies?Molecular mechanisms of dopaminergic subset specification: fundamental aspects and clinical perspectives.
P2860
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P248
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P2860
Wnt1-lmx1a forms a novel autoregulatory loop and controls midbrain dopaminergic differentiation synergistically with the SHH-FoxA2 pathway
description
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
im Dezember 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/12/04)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/12/04)
@nl
наукова стаття, опублікована в грудні 2009
@uk
مقالة علمية نشرت في 4-12-2009 حول موضوع: دماغ
@ar
name
Wnt1-lmx1a forms a novel autor ...... lly with the SHH-FoxA2 pathway
@ast
Wnt1-lmx1a forms a novel autor ...... lly with the SHH-FoxA2 pathway
@en
Wnt1-lmx1a forms a novel autor ...... lly with the SHH-FoxA2 pathway
@nl
type
label
Wnt1-lmx1a forms a novel autor ...... lly with the SHH-FoxA2 pathway
@ast
Wnt1-lmx1a forms a novel autor ...... lly with the SHH-FoxA2 pathway
@en
Wnt1-lmx1a forms a novel autor ...... lly with the SHH-FoxA2 pathway
@nl
prefLabel
Wnt1-lmx1a forms a novel autor ...... lly with the SHH-FoxA2 pathway
@ast
Wnt1-lmx1a forms a novel autor ...... lly with the SHH-FoxA2 pathway
@en
Wnt1-lmx1a forms a novel autor ...... lly with the SHH-FoxA2 pathway
@nl
P2093
P2860
P921
P3181
P1433
P1476
Wnt1-lmx1a forms a novel autor ...... lly with the SHH-FoxA2 pathway
@en
P2093
Amanda Leung
Baek-Soo Han
Chun-Hyung Kim
Jung-Il Moon
Kwang-Soo Kim
Mi-Yoon Chang
Sangmi Chung
Sunghoi Hong
P2860
P304
P3181
P356
10.1016/J.STEM.2009.09.015
P407
P577
2009-12-01T00:00:00Z