Genomic characterization of Gli-activator targets in sonic hedgehog-mediated neural patterning
about
Boolean modelling reveals new regulatory connections between transcription factors orchestrating the development of the ventral spinal cordGLI2-specific transcriptional activation of the bone morphogenetic protein/activin antagonist follistatin in human epidermal cellsEstablishing and interpreting graded Sonic Hedgehog signaling during vertebrate neural tube patterning: the role of negative feedbackMorphogen rules: design principles of gradient-mediated embryo patterningAdrenocortical zonation, renewal, and remodelingThe many faces of neuroendocrine differentiation in prostate cancer progressionContext-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapySOX9 inhibits β-TrCP-mediated protein degradation to promote nuclear GLI1 expression and cancer stem cell properties.Wnt1-lmx1a forms a novel autoregulatory loop and controls midbrain dopaminergic differentiation synergistically with the SHH-FoxA2 pathwayGli1 protein regulates the S-phase checkpoint in tumor cells via Bid protein, and its inhibition sensitizes to DNA topoisomerase 1 inhibitorsCyclopamine tartrate, an inhibitor of Hedgehog signaling, strongly interferes with mitochondrial function and suppresses aerobic respiration in lung cancer cellsDistinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud developmentMouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathwayGenome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitorsMir-17-3p controls spinal neural progenitor patterning by regulating Olig2/Irx3 cross-repressive loopFoxf genes integrate tbx5 and hedgehog pathways in the second heart field for cardiac septationSox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewalFoxF1 and FoxL1 link hedgehog signaling and the control of epithelial proliferation in the developing stomach and intestineCilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conservedSix2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networksPossible functional links among brain- and skull-related genes selected in modern humansMesocortical Dopamine Phenotypes in Mice Lacking the Sonic Hedgehog Receptor CdonFoxj1 regulates floor plate cilia architecture and modifies the response of cells to sonic hedgehog signallingUrogenital development in Pallister-Hall syndrome is disrupted in a cell-lineage-specific manner by constitutive expression of GLI3 repressor.GLI1 is a central mediator of EWS/FLI1 signaling in Ewing tumors.Non-consensus GLI binding sites in Hedgehog target gene regulation.An epigenetic biomarker panel for glioblastoma multiforme personalized medicine through DNA methylation analysis of human embryonic stem cell-like signature.Genomic characterization of Wilms' tumor suppressor 1 targets in nephron progenitor cells during kidney development.Regulation of sonic hedgehog-GLI1 downstream target genes PTCH1, Cyclin D2, Plakoglobin, PAX6 and NKX2.2 and their epigenetic status in medulloblastoma and astrocytoma.Shh pathway activation is present and required within the vertebrate limb bud apical ectodermal ridge for normal autopod patterningAscl1/Mash1 is a novel target of Gli2 during Gli2-induced neurogenesis in P19 EC cells.Mechanism and evolution of cytosolic Hedgehog signal transductionDifferential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development.Hedgehog pathway-regulated gene networks in cerebellum development and tumorigenesis.Sonic hedgehog signaling in the postnatal brain.SUMOylation by Pias1 regulates the activity of the Hedgehog dependent Gli transcription factorsExpression of DNMT1 and DNMT3a are regulated by GLI1 in human pancreatic cancer.Development of posterior hypothalamic neurons enlightens a switch in the prosencephalic basic plan.MotifMap: integrative genome-wide maps of regulatory motif sites for model species.Yeast-based assay identifies novel Shh/Gli target genes in vertebrate development
P2860
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P2860
Genomic characterization of Gli-activator targets in sonic hedgehog-mediated neural patterning
description
2007 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im April 2007 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2007/05/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/05/01)
@nl
наукова стаття, опублікована в травні 2007
@uk
مقالة علمية (نشرت في مايو 2007)
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name
Genomic characterization of Gl ...... hog-mediated neural patterning
@ast
Genomic characterization of Gl ...... hog-mediated neural patterning
@en
Genomic characterization of Gl ...... hog-mediated neural patterning
@nl
type
label
Genomic characterization of Gl ...... hog-mediated neural patterning
@ast
Genomic characterization of Gl ...... hog-mediated neural patterning
@en
Genomic characterization of Gl ...... hog-mediated neural patterning
@nl
prefLabel
Genomic characterization of Gl ...... hog-mediated neural patterning
@ast
Genomic characterization of Gl ...... hog-mediated neural patterning
@en
Genomic characterization of Gl ...... hog-mediated neural patterning
@nl
P2093
P3181
P356
P1433
P1476
Genomic characterization of Gl ...... hog-mediated neural patterning
@en
P2093
Andrew P McMahon
Eric H Davidson
Hongkai Ji
Scott McCuine
Shane Giles
Sheng Zhong
Toyoaki Tenzen
William J R Longabaugh
Wing H Wong
P304
P3181
P356
10.1242/DEV.001966
P407
P577
2007-04-18T00:00:00Z